日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Remote homology and functional genetics unmask deeply preserved Scm3/HJURP orthologs in metazoans.

远程同源性和功能遗传学揭示了后生动物中深层保守的 Scm3/HJURP 直系同源物。

Hollis Jeremy A, Stonick Jason A, Topalidou Irini, Young Janet M, Moens Cecilia B, Lehrbach Nicolas J, Campbell Melody G, Malik Harmit S

Protein sequence editing defines distinct and overlapping functions of SKN-1A/Nrf1 and SKN-1C/Nrf2

蛋白质序列编辑定义了SKN-1A/Nrf1和SKN-1C/Nrf2各自独特且重叠的功能。

Jochim, Briar E; Topalidou, Irini; Lehrbach, Nicolas J

Lysine deficiency within a conserved lysine desert is critical for EEL-1/HUWE1 to support ubiquitin proteasome system function

在保守的赖氨酸沙漠区域内,赖氨酸缺乏对于 EEL-1/HUWE1 支持泛素-蛋白酶体系统功能至关重要。

Yanagi, Katherine S; Chen, Brenda J; Kunjo, Sheikh Omar; Topalidou, Irini; Lehrbach, Nicolas

Mutations in nucleotide metabolism genes bypass proteasome defects in png-1/NGLY1-deficient Caenorhabditis elegans

核苷酸代谢基因突变绕过了 png-1/NGLY1 缺陷型秀丽隐杆线虫中的蛋白酶体缺陷

Katherine S Yanagi, Briar Jochim, Sheikh Omar Kunjo, Peter Breen, Gary Ruvkun, Nicolas Lehrbach

Decreased Hsp90 activity protects against TDP-43 neurotoxicity in a C. elegans model of amyotrophic lateral sclerosis

在肌萎缩侧索硬化症秀丽隐杆线虫模型中,降低 Hsp90 活性可防止 TDP-43 神经毒性

Laura Garcia-Toscano, Heather N Currey, Joshua C Hincks, Jade G Stair, Nicolas J Lehrbach, Nicole F Liachko

An antisteatosis response regulated by oleic acid through lipid droplet-mediated ERAD enhancement

油酸通过脂滴介导的 ERAD 增强调节抗脂肪变性反应

Jorge Iván Castillo-Quan, Michael J Steinbaugh, Laura Paulette Fernández-Cárdenas, Nancy K Pohl, Ziyun Wu, Feimei Zhu, Natalie Moroz, Veronica Teixeira, Monet S Bland, Nicolas J Lehrbach, Lorenza Moronetti, Magdalena Teufl, T Keith Blackwell

Regulation and Functions of the ER-Associated Nrf1 Transcription Factor

内质网相关Nrf1转录因子的调控和功能

Ruvkun, Gary; Lehrbach, Nicolas

Anxiety sensitivity and experiential avoidance: Relations with anxiety severity and treatment outcomes in anxious youth

焦虑敏感性和体验回避:与焦虑青少年焦虑严重程度和治疗结果的关系

Lehrbach, Kyler R; Crane, Margaret E; Olino, Thomas M; Kendall, Philip C

Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility

秀丽隐杆线虫必需的 Argonaute CSR-1 的两种亚型对精子和卵母细胞生育力有差异的调节

Amanda G Charlesworth, Uri Seroussi, Nicolas J Lehrbach, Mathias S Renaud, Adam E Sundby, Ruxandra I Molnar, Robert X Lao, Alexandra R Willis, Jenna R Woock, Matthew J Aber, Annette J Diao, Aaron W Reinke, Gary Ruvkun, Julie M Claycomb

Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression

肽:N-聚糖酶对 SKN-1A/Nrf1 的蛋白质序列编辑控制蛋白酶体基因表达

Nicolas J Lehrbach, Peter C Breen, Gary Ruvkun