日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

YL1004 is a SARS-CoV-2 papain-like protease inhibitor with immunomodulatory and antiviral activity in mice

YL1004 是一种 SARS-CoV-2 木瓜蛋白酶样蛋白酶抑制剂，在小鼠中具有免疫调节和抗病毒活性。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68795-5
Nan, Jinshan; Shuai, Huiping; Qiao, Jingxin; Zeng, Rui; Du, Lianzhao; Chen, Yan; Yoon, Chaemin; Hu, Jiaheng; Guo, Wenyu; Wang, Lei; Huang, Chong; Zhu, Lengjing; Li, Yueshan; Zhang, Shanshan; Deng, Xinyue; Sun, Jingxuan; Du, Le; Ma, Ronggang; Huang, Qiao; Lei, Jian; Chu, Hin; Yang, Shengyong
微生物学
SARS-CoV-2
免疫/内分泌
发表日期：2026
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Galangin 3-methyl ether alleviates mouse hypertrophic cardiomyopathy via targeting HDAC2 and subsequently inactivating the PI3K-AKT signaling pathway

高良姜素3-甲基醚通过靶向HDAC2并随后抑制PI3K-AKT信号通路，从而缓解小鼠肥厚型心肌病。

期刊:Acta Pharmacologica Sinica
影响因子:8.4
doi:10.1038/s41401-025-01676-7
Zhang, Ke; Xu, Tao; Heng, Xin-Yu; Lei, Jian-Zhen; Han, De-Shen; Huang, Shao-Hong; He, Mei-Qi; Pu, Lin; Wu, Yue-Yue; Sun, Ning; Yang, Hai; Ye, Chao
心肌病
信号转导
HDAC2
心血管
AKT
发表日期：2026
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Associations between non-optimum temperatures and cardiovascular hospital admissions and effect modification by ambient particulate air pollution: a two-stage time-series study in China

非适宜温度与心血管疾病住院率之间的关联及其受环境颗粒物空气污染的影响：一项在中国开展的两阶段时间序列研究

期刊:The Lancet Regional Health Western Pacific
影响因子:8.1
doi:10.1016/j.lanwpc.2026.101829
Liu, Huimeng; Lei, Jian; Jiang, Yunxing; Bai, Lijun; Wang, Kai; Yang, Chenlu; Li, Ge; Chen, Juan; Lan, Yang; Xia, Xi; Wang, Jinxi; Wei, Chen; Li, Yinxiang; Liu, Yuewei; Wei, Jing; Sun, Shengzhi; Deng, Furong; Guo, Xinbiao; Chen, Xi; Wu, Shaowei
心血管疾病
心血管
发表日期：2026
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An intrinsic loop-mediated structural stability modulating inhibitor potency in the SADS-CoV and SARS-CoV-2 main proteases

SADS-CoV 和 SARS-CoV-2 主蛋白酶中固有的环介导的结构稳定性调节抑制剂效力

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1013981
Zeng, Rui; Cui, Shizhan; Xia, Xiaoyan; Huang, Chong; Sun, Jingxuan; Deng, Xinyue; Gui, Qiaoling; Fan, Huahao; Liu, Xiaojuan; Yu, Yang; Yang, Shengyong; Lei, Jian
SARS-CoV-2
发表日期：2026
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Research on multi-scale feature detection of open-pit mine road cracks

露天矿道路裂缝多尺度特征检测研究

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-026-37153-2
Wang, Liang; Zhao, Meiling; Yu, Zehao; Yang, Guangxin; Wang, Qingxu; Liu, Guangwei; Lei, Jian
发表日期：2026
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Vision-Based Detection of Large Coal Fragments in Fully Mechanized Mining Faces Using Adaptive Weighted Attention and Transfer Learning

基于自适应加权注意力机制和迁移学习的全机械化采煤工作面大型煤块视觉检测

期刊:Sensors
影响因子:3.5
doi:10.3390/s26041167
Wang, Yuan; Lei, Jian; Li, Leping; Lu, Zhengxiong; Xu, Lele; Zhao, Shuanfeng
发表日期：2026
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A recombinant protein vaccine induces protective immunity against SARS-CoV-2 JN.1 and XBB-lineage subvariants.

重组蛋白疫苗可诱导针对 SARS-CoV-2 JN.1 和 XBB 谱系亚变种的保护性免疫

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02154-6
Yang Jingyun, Hong Weiqi, Shi Huashan, Wang Zhenling, He Cai, Lei Hong, Yan Hong, Alu Aqu, Ao Danyi, Chen Zimin, Zhou Yanan, Yang Hao, Yang Yun, Yu Wenhai, Tang Cong, Wang Junbin, Li Bai, Huang Qing, Hu Hongbo, Cheng Wei, Dong Haohao, Lei Jian, Chen Lu, Zhou Xikun, Yang Li, Wang Wei, Shen Guobo, Yang Jinliang, Zhao Zhiwei, Song Xiangrong, Sun Qiangming, Wang Youchun, Lu Shuaiyao, Li Jiong, Lu Guangwen, Li Weimin, Wei Yuquan, Wei Xiawei
炎症/感染
新冠
发表日期：2025
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Nasal Staphylococcus aureus carriage promotes depressive behaviour in mice via sex hormone degradation.

鼻腔内金黄色葡萄球菌的携带会通过降解性激素促进小鼠的抑郁行为。

期刊:Nature Microbiology
影响因子:19.4
doi:10.1038/s41564-025-02120-6
Xiang Guoxiu, Wang Yanan, Ni Kaiji, Luo Huoqing, Liu Qian, Song Yan, Miao Ping, He Lei, Jian Ying, Yang Ziyu, Chen Tianchi, Xu Ke, Sun Xia, Shen Zhen, Ji Chenfeng, Zhao Na, He Mengxin, Pan Yan, Luo Yanli, Hu Ji, Otto Michael, Li Min
神经科学
免疫/内分泌
发表日期：2025
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Respiratory Benefits of Multisetting Air Purification in Children: A Cluster Randomized Crossover Trial

多模式空气净化对儿童呼吸系统的益处：一项整群随机交叉试验

期刊:Jama Pediatrics
影响因子:18
doi:10.1001/jamapediatrics.2024.5049
Lei, Jian; Sun, Qinghua; Chen, Renjie; Zhu, Yixiang; Zhou, Lu; Xue, Xiaowei; Fang, Jianlong; Du, Yanjun; Wang, Yanwen; Li, Tiantian; Kan, Haidong
发表日期：2025
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Author Correction: An orally available M(pro)/TMPRSS2 bispecific inhibitor with potent anti-coronavirus efficacy in vivo

作者更正：一种口服有效的M(pro)/TMPRSS2双特异性抑制剂在体内具有强大的抗冠状病毒功效

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67654-z
Shuai, Huiping; Qiao, Jingxin; Yoon, Chaemin; Zhang, Guo; Hou, Yuxin; Xia, Xiaoyan; Wang, Lei; Deng, Xinyue; Wang, Yifei; Li, Qingquan; Du, Lianzhao; Liu, Yuanchen; Zhou, Minmin; Wong, Hoi Ting; Hu, Jiaheng; Liu, Huan; Hu, Bingjie; Wang, Dong; Su, Jingyi; Pan, Yuying; Ye, Yongtao; Chen, Yan; Fang, Zhen; Xia, Ziyi; Chai, Yue; Shi, Jialu; Wang, Yang; Zhu, Tianrenzheng; Zhang, Honglei; Yuan, Shuofeng; Zhou, Jie; Chan, Jasper Fuk-Woo; Yuen, Kwok-Yung; Xu, Chunfu; Lei, Jian; Yang, Shengyong; Chu, Hin
微生物学
发表日期：2025
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