Lei Zhe相关文献与解析，生知库 | 链接生命科学的每一步

Primary tissue metabolic fingerprinting for efficient diagnosis of lymph node metastasis and metabolic reprogramming mechanisms in colorectal cancer.

利用原发组织代谢指纹图谱有效诊断结直肠癌淋巴结转移和代谢重编程机制。

doi:10.1016/j.mtbio.2025.102712

Zhang Hao, Zhang Juxiang, Yan Meng, Liu Xiaohui, Yang Shouzhi, Wu Jiao, Huang Shan, Guo Xia, Zhu Weidong, Wang Jingyi, Lei Zhe, Zhang Ding, Zhu Changbin, Ruan Li, Liang Zhiyong, Guo Lingchuan, Huang Yida

Correction: Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-induced epithelialmesenchymal transition and metastasis by controlling TIF1 in non-small cell lung cancer

更正：环状RNA hsa_circ_0008305 (circPTK2) 通过调控TIF1抑制非小细胞肺癌中TGF诱导的上皮间质转化和转移

期刊:Molecular Cancer

影响因子:33.9

doi:10.1186/s12943-025-02509-1

Wang, Longqiang; Tong, Xin; Zhou, Zhengyu; Wang, Shengjie; Lei, Zhe; Zhang, Tianze; Liu, Zeyi; Zeng, Yuanyuan; Li, Chang; Zhao, Jun; Su, Zhiyue; Zhang, Cuijuan; Liu, Xia; Xu, Guangquan; Zhang, Hong-Tao

Microbiota-derived H2S induces c-kit+ cDC1 autophagic cell death and liver inflammation in metabolic dysfunction-associated steatohepatitis

微生物群来源的H2S诱导c-kit+ cDC1自噬性细胞死亡和代谢功能障碍相关性脂肪性肝炎中的肝脏炎症

期刊:Nature Communications

影响因子:14.7

doi:10.1038/s41467-025-57574-3

Yuxiang Song # ，Na Li # ，Shang Jiang # ，Kexin Wang # ，Guoyue Lv ，Zhongqi Fan ，Xiliang Du ，Wenwen Gao ，Lin Lei ，Zhe Wang ，Guowen Liu ，Xinwei Li

Acetylation-dependent USP7-TRIM25 axis drives oncogenic progression in non-small cell lung cancer.

乙酰化依赖的 USP7-TRIM25 轴驱动非小细胞肺癌的致癌进展。

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-025-08034-9

Yang Jian, Chen Zhike, Hu Wenxuan, Zeng Weibiao, Lei Zhe, Tong Xin, Li Qifan, Luo Gaomeng, Hu Kang, Chen Zhimeng, Liu Zeyi, Li Chang, Xu Chun, Ding Cheng, Zhang Hong-Tao, Zhao Jun

PKIB facilitates bladder cancer proliferation and metastasis through mediation of HSP27 phosphorylation by PKA.

PKIB 通过 PKA 介导 HSP27 磷酸化，促进膀胱癌的增殖和转移

期刊:Cell Death & Disease

影响因子:9.6

doi:10.1038/s41419-025-07814-7

Liu Xiaolong, Yin Xiaoyu, Yuan Feng, Li Shiqing, Xiao Fei, Zhou Feng, Pan Xudong, Ho Yatfaat, Dong Shuo, Xu Duan, Ma Yunqing, Cao Zhengding, Lei Zhe, Sun Yi

The SWI/SNF chromatin-remodeling subunit DPF2 regulates macrophage inflammation in intestinal injury via the CACNA1D-mediated MAPK pathway

SWI/SNF染色质重塑亚基DPF2通过CACNA1D介导的MAPK通路调控肠道损伤中的巨噬细胞炎症。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.2518762122

Ji, Mintao; Liang, Haisheng; Dong, Shuai; Guo, Yuhan; Lin, Yiping; Zhang, Hong; Wang, Yuhong; Lei, Zhe; Xu, Xiaoya; Shu, Yinyin; Zhang, Zhisen; Jin, Xiaoni; Lu, Shuangshuang; Zhang, Wensheng; Guo, Lingchuan; Shao, Chunlin; Chang, Lei

ZMIZ2 interacts with PIN1 to promote lung adenocarcinoma EMT and metastasis via activation of the PI3K/AKT pathway.

ZMIZ2 与 PIN1 相互作用，通过激活 PI3K/AKT 通路促进肺腺癌 EMT 和转移。

期刊:Cell and Bioscience

影响因子:6.2

doi:10.1186/s13578-025-01522-7

Su Zhiyue, Wang Yuhong, Jin Ersuo, Wang Feifei, Zhang Weiwei, Zhang Yingxi, Liu Zeyi, Wang Shengjie, Yang Hongli, Qi Chang, Gu DongMei, Liu Xia, Guo Lingchuan, Zhang Hong-Tao, Lei Zhe

Spleen granulopoiesis in psoriasis immune microenvironment aggravates psoriasis via IL-6/P-STAT3 signaling

银屑病免疫微环境中的脾脏粒细胞生成通过IL-6/P-STAT3信号通路加重银屑病

期刊:Biology Direct

影响因子:4.9

doi:10.1186/s13062-025-00675-2

Shi, Feng; Gong, Pixia; Huang, Shan; Zhu, Weidong; Shi, Chenxi; Qi, Chang; Lei, Zhe; Ding, Yayun

Spatially resolved whole-transcriptomic profiling of EGFR-mutated lung adenocarcinomas stratified by PD-L1 expression.

根据 PD-L1 表达对 EGFR 突变肺腺癌进行空间分辨的全转录组分析。

期刊:Cellular Oncology

影响因子:4.8

doi:10.1007/s13402-025-01143-9

Yu Chenxi, Shi Chenxi, Zhou Hao, Li Na, Ma Ruyi, Liu SongBai, Tang Zaixiang, Zhang Xianling, Lei Zhe, Qin Hualong

Engineered Bacteria-Vesicle Delivered Lactate Reprogramming Boosts Tumor Radiosensitivity.

工程化细菌囊泡递送乳酸重编程可提高肿瘤放射敏感性。

Primary tissue metabolic fingerprinting for efficient diagnosis of lymph node metastasis and metabolic reprogramming mechanisms in colorectal cancer.

利用原发组织代谢指纹图谱有效诊断结直肠癌淋巴结转移和代谢重编程机制。

Correction: Circular RNA hsa_circ_0008305 (circPTK2) inhibits TGF-induced epithelialmesenchymal transition and metastasis by controlling TIF1 in non-small cell lung cancer

更正：环状RNA hsa_circ_0008305 (circPTK2) 通过调控TIF1抑制非小细胞肺癌中TGF诱导的上皮间质转化和转移

Microbiota-derived H2S induces c-kit+ cDC1 autophagic cell death and liver inflammation in metabolic dysfunction-associated steatohepatitis

微生物群来源的H2S诱导c-kit+ cDC1自噬性细胞死亡和代谢功能障碍相关性脂肪性肝炎中的肝脏炎症

Acetylation-dependent USP7-TRIM25 axis drives oncogenic progression in non-small cell lung cancer.

乙酰化依赖的 USP7-TRIM25 轴驱动非小细胞肺癌的致癌进展。

PKIB facilitates bladder cancer proliferation and metastasis through mediation of HSP27 phosphorylation by PKA.

PKIB 通过 PKA 介导 HSP27 磷酸化，促进膀胱癌的增殖和转移

The SWI/SNF chromatin-remodeling subunit DPF2 regulates macrophage inflammation in intestinal injury via the CACNA1D-mediated MAPK pathway

SWI/SNF染色质重塑亚基DPF2通过CACNA1D介导的MAPK通路调控肠道损伤中的巨噬细胞炎症。

ZMIZ2 interacts with PIN1 to promote lung adenocarcinoma EMT and metastasis via activation of the PI3K/AKT pathway.

ZMIZ2 与 PIN1 相互作用，通过激活 PI3K/AKT 通路促进肺腺癌 EMT 和转移。

Spleen granulopoiesis in psoriasis immune microenvironment aggravates psoriasis via IL-6/P-STAT3 signaling

银屑病免疫微环境中的脾脏粒细胞生成通过IL-6/P-STAT3信号通路加重银屑病

Spatially resolved whole-transcriptomic profiling of EGFR-mutated lung adenocarcinomas stratified by PD-L1 expression.

根据 PD-L1 表达对 EGFR 突变肺腺癌进行空间分辨的全转录组分析。