日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Branched-Chain α Keto-Acid Dehydrogenase Kinase-Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance.

支链α-酮酸脱氢酶激酶介导的AKT磷酸化促进肾细胞癌的肿瘤发生和耐药性。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202411081
Tian Qin, Wang Jinxiang, Li Qiji, Liu Yangruiyu, Chen Yanping, Feng Jiacheng, Lei Zi-Ning, Patel Harsh, Cai Chao-Yun, Xu Yuzhi, Quan Chuntao, Fei Lingyan, Xiao Zexiu, Fang Shuo, Lin Tianxin, Chen Zhe-Sheng, Liu Yuchen, Zeng Leli, Pan Yihang
细胞生物学
AKT
PI3K/Akt
磷酸化
发表日期：2025
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RN486, a Bruton's Tyrosine Kinase inhibitor, antagonizes multidrug resistance in ABCG2-overexpressing cancer cells

RN486是一种布鲁顿酪氨酸激酶抑制剂，可拮抗ABCG2过表达癌细胞的多药耐药性。

期刊:Journal of Translational Internal Medicine
影响因子:7.4
doi:10.2478/jtim-2024-0011
Dong, Xing-Duo; Lu, Qisi; Li, Yi-Dong; Cai, Chao-Yun; Teng, Qiu-Xu; Lei, Zi-Ning; Wei, Zeng-Hui; Yin, Fan; Zeng, Leli; Chen, Zhe-Sheng
ABCG2
肿瘤
肿瘤免疫
信号转导
细胞生物学
发表日期：2024
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The correlation between cancer stem cells and epithelial-mesenchymal transition: molecular mechanisms and significance in cancer theragnosis

癌症干细胞与上皮-间质转化之间的相关性：分子机制及其在癌症诊疗中的意义

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2024.1417201
Lei, Zi-Ning; Teng, Qiu-Xu; Koya, Jagadish; Liu, Yangruiyu; Chen, Zizhou; Zeng, Leli; Chen, Zhe-Sheng; Fang, Shuo; Wang, Jinxiang; Liu, Yuchen; Pan, Yihang
肿瘤
肿瘤免疫
细胞生物学
干细胞
发育与干细胞
发表日期：2024
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Understanding and targeting resistance mechanisms in cancer

了解并靶向癌症耐药机制

期刊:MedComm
影响因子:10.7
doi:10.1002/mco2.265
Lei, Zi-Ning; Tian, Qin; Teng, Qiu-Xu; Wurpel, John N D; Zeng, Leli; Pan, Yihang; Chen, Zhe-Sheng
肿瘤
肿瘤免疫
发表日期：2023
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Signaling pathways and therapeutic interventions in gastric cancer

胃癌的信号通路和治疗干预

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-022-01190-w
Lei, Zi-Ning; Teng, Qiu-Xu; Tian, Qin; Chen, Wei; Xie, Yuhao; Wu, Kaiming; Zeng, Qianlin; Zeng, Leli; Pan, Yihang; Chen, Zhe-Sheng; He, Yulong
胃癌
信号转导
肿瘤
肿瘤免疫
发表日期：2022
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PBK/TOPK inhibitor OTS964 resistance is mediated by ABCB1-dependent transport function in cancer: in vitro and in vivo study

PBK/TOPK抑制剂OTS964耐药性是由癌症中ABCB1依赖性转运功能介导的：体外和体内研究

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-022-01512-0
Yang, Yuqi; Teng, Qiu-Xu; Wu, Zhuo-Xun; Wang, Jing-Quan; Lei, Zi-Ning; Lusvarghi, Sabrina; Ambudkar, Suresh V; Ji, Ning; Chen, Zhe-Sheng
肿瘤
TOPK
肿瘤免疫
ABCB1
发表日期：2022
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Digoxin targets low density lipoprotein receptor-related protein 4 and protects against osteoarthritis

地高辛靶向低密度脂蛋白受体相关蛋白4，并能预防骨关节炎。

期刊:Annals of the Rheumatic Diseases
影响因子:20.6
doi:10.1136/annrheumdis-2021-221380
Wang, Kai-di; Ding, Xiang; Jiang, Nan; Zeng, Chao; Wu, Jing; Cai, Xian-Yi; Hettinghouse, Aubryanna; Khleborodova, Asya; Lei, Zi-Ning; Chen, Zhe-Sheng; Lei, Guang-Hua; Liu, Chuan-Ju
信号转导
关节炎
发表日期：2022
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Reconstruction of intestinal microecology of type 2 diabetes by fecal microbiota transplantation: Why and how

通过粪便微生物移植重建2型糖尿病肠道微生态：原因和方法

期刊:Bosnian Journal of Basic Medical Sciences
影响因子:3.4
doi:10.17305/bjbms.2021.6323
Hou, Kaijian; Zhang, Shuo; Wu, Zezhen; Zhu, Dan; Chen, Fengwu; Lei, Zi-Ning; Liu, Weiting; Xiao, Chuanxing; Chen, Zhe-Sheng
微生物学
糖尿病
代谢
发表日期：2022
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Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction

通过基于ELISA的筛选方法，寻找抑制RBD/ACE2相互作用的药物，从而将FDA批准的药物重新用于SARS-CoV-2感染。

期刊:Protein & Cell
影响因子:12.8
doi:10.1007/s13238-020-00803-w
Fu, Wenyu; Chen, Yujianan; Wang, Kaidi; Hettinghouse, Aubryanna; Hu, Wenhuo; Wang, Jing-Quan; Lei, Zi-Ning; Chen, Zhe-Sheng; Stapleford, Kenneth A; Liu, Chuan-Ju
炎症/感染
ACE2
SARS-CoV-2
发表日期：2021
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Insights on the structure-function relationship of human multidrug resistance protein 7 (MRP7/ABCC10) from molecular dynamics simulations and docking studies

通过分子动力学模拟和分子对接研究，深入了解人类多药耐药蛋白7 (MRP7/ABCC10) 的结构-功能关系

期刊:MedComm
影响因子:10.7
doi:10.1002/mco2.65
Wang, Jing-Quan; Cui, Qingbin; Lei, Zi-Ning; Teng, Qiu-Xu; Ji, Ning; Lin, Lusheng; Liu, Zhijun; Chen, Zhe-Sheng
MRP7
发表日期：2021
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