SHP2 is overexpressed and inhibits pSTAT1-mediated APM component expression, T-cell attracting chemokine secretion, and CTL recognition in head and neck cancer cells.
SHP2 在头颈癌细胞中过度表达，抑制 pSTAT1 介导的 APM 成分表达、T 细胞趋化因子分泌和 CTL 识别
期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-12-1517
Leibowitz Michael S, Srivastava Raghvendra M, Andrade Filho Pedro A, Egloff Ann Marie, Wang Lin, Seethala Raja R, Ferrone Soldano, Ferris Robert L
