Remethylation of Dnmt3a(-/-) hematopoietic cells is associated with partial correction of gene dysregulation and reduced myeloid skewing
Dnmt3a(-/-)造血细胞的再甲基化与基因失调的部分纠正和髓系偏倚的减少有关。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1918611117
Ketkar, Shamika; Verdoni, Angela M; Smith, Amanda M; Bangert, Celia V; Leight, Elizabeth R; Chen, David Y; Brune, Meryl K; Helton, Nichole M; Hoock, Mieke; George, Daniel R; Fronick, Catrina; Fulton, Robert S; Ramakrishnan, Sai Mukund; Chang, Gue Su; Petti, Allegra A; Spencer, David H; Miller, Christopher A; Ley, Timothy J