日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Investigation of a clinical trial drug VV261 as a potent antiviral candidate against Chikungunya virus

对临床试验药物VV261作为对抗基孔肯雅病毒的有效抗病毒候选药物进行研究

期刊:Signal Transduction and Targeted Therapy
影响因子:52.7
doi:10.1038/s41392-025-02567-3
Zhang, Yumin; Tang, Sheng; Chen, Lu; Song, Shufen; Cao, Junyuan; Tian, Guanghui; Xiao, Gengfu; Shen, Jingshan; Zhang, Leike
微生物学
发表日期：2026
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Structure-Based Development of Ultra-Broad-Spectrum 3C-Like Protease Inhibitors

基于结构的超广谱3C样蛋白酶抑制剂的开发

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202512342
Su, Haixia; Nie, Tianqing; Chen, Guofeng; Xiong, Muya; Zhang, Yumin; Wu, Guoqing; You, Mengyuan; Xie, Hang; He, Jian; Xiong, Yanchao; Hu, Hangchen; Zhao, Wenfeng; Li, Minjun; Xiao, Gengfu; Zhang, Leike; Xu, Yechun
发表日期：2026
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Affinity-optimized TROP2 antibodies support potent antitumor activity in antibody-drug conjugates

亲和力优化的TROP2抗体支持抗体药物偶联物中强大的抗肿瘤活性

期刊:Antibody Therapeutics
影响因子:4.5
doi:10.1093/abt/tbag011
Yamaguchi, Aiko; Hong, Junping; Li, Leike; Kobayashi, Kiyotaka; Yamazaki, Chisato M; Ha, Summer Y Y; Anami, Yasuaki; Xiong, Wei; Liu, Junquan; An, Zhiqiang; Zhang, Ningyan; Tsuchikama, Kyoji
肿瘤
肿瘤免疫
发表日期：2026
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Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease

猴痘病毒I7L蛋白酶的动态帽介导底物进入和强效抑制剂设计

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202501625
Su, Haixia; Wu, Guoqing; Xiong, Muya; Wang, Yuhang; Cao, Junyuan; You, Mengyuan; Xiang, Yingchun; Nie, Tianqing; Li, Minjun; Xiao, Gengfu; Zhang, Leike; Shao, Qiang; Xu, Yechun
微生物学
猴痘
Monkey
发表日期：2025
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Targeting viral suppressor of RNAi confers anti-coronaviral activity

靶向RNAi病毒抑制因子可赋予抗冠状病毒活性

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2024.12.009
Chen, Jiyao; Mu, JingFang; Zhou, Kangping; Zhang, Yuming; Zhang, Jieling; Shu, Ting; Shang, Weijuan; Ren, Yujie; Xu, Xi-Qiu; Zhang, Leike; Yuan, Shuai; Zhang, Dingyu; Cai, Kun; Qiu, Yang; Zhou, Xi
微生物学
发表日期：2025
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Virus envelope glycoprotein targeting bispecific T cell engager protects mice from lethal severe fever with thrombocytopenia virus infection

靶向病毒包膜糖蛋白的双特异性T细胞衔接器可保护小鼠免受致命性高热伴血小板减少症病毒感染。

期刊:Cell Reports Medicine
影响因子:11.7
doi:10.1016/j.xcrm.2025.102458
Xuefang Peng,Wei Wang,Yuexia Liang,Yi Jian,Qiaoyue Wei,Tong Yang,Chaojie Wang,Xiaohong Yin,Mingjuan Du,Hang Shang,Ruobing Liu,Xi Wang,Xing Shang,Nanxin Gong,Yanqin Xu,Chunlei Wang,Ning Cui,Leike Zhang,Yu Guo,Wei Liu,Hongkai Zhang,Hao Li
细胞生物学
毒理研究
T细胞
血小板
T细胞
发表日期：2025
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The oral nucleoside drug VV116 is a promising candidate for treating Nipah virus infection

口服核苷类药物VV116是治疗尼帕病毒感染的一种很有前景的候选药物。

期刊:Emerging Microbes & Infections
影响因子:7.5
doi:10.1080/22221751.2025.2587983
Zhang, Yumin; Yao, Yanfeng; Song, Shufen; Gao, Ge; Peng, Yun; Liu, Hang; Chen, Miaoyu; Zheng, Wei; Tian, Guanghui; Xie, Yuanchao; Shen, Jingshan; Xiao, Gengfu; Hu, Tianwen; Shan, Chao; Zhang, Leike
炎症/感染
微生物学
发表日期：2025
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Ovariectomy Induces Selective Alterations in Dura Mater Blood and Lymphatic Microvascular Network Architecture in Mice.

卵巢切除术可选择性地改变小鼠硬脑膜血液和淋巴微血管网络结构。

期刊:Cells
影响因子:5.2
doi:10.3390/cells14211647
Glinskii Olga V, Toubal Imad Eddine, Xie Leike, Sinha Sunilima, Palaniappan Kannappan, Glinsky Vladislav V
心血管
发表日期：2025
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Discovery and mechanistic insights of dibenzoylmethane as a broad spectrum inhibitor of coronavirus.

二苯甲酰甲烷作为冠状病毒广谱抑制剂的发现和机制研究

期刊:PLoS Pathogens
影响因子:4.9
doi:10.1371/journal.ppat.1013492
Sun Yuan, Shu Xiaoyang, Chen Lu, Shang Weijuan, Zhang Yumin, Xiao Gengfu, Zhang Leike
信号转导
发表日期：2025
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An orally available 4'-fluorouridine prodrug inhibits SFTSV and LCMV infection

口服的4'-氟尿苷前药可抑制SFTSV和LCMV感染

期刊:Journal of Virology
影响因子:3.8
doi:10.1128/jvi.01172-25
Jian, Xiaoqin; Hu, Tianwen; Xu, Huan; Wen, Yuxi; Zhang, Yumin; Xu, Mengwei; Jiang, Xiaming; Cao, Junyuan; Xiang, Li; Shen, Jingshan; Tian, Guanghui; Xiao, Gengfu; Zhang, Leike
炎症/感染
发表日期：2025
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