日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cross-coronavirus host susceptibility loci influence disease severity through immune mediators

冠状病毒宿主易感基因位点通过免疫介质影响疾病严重程度

Risemberg, Ellen L; Leist, Sarah R; Schäfer, Alexandra; Kamat, Kalika D; Bell, Timothy A; Hock, Pablo; Jensen, Kara L; Linnertz, Colton L; Miller, Darla R; Shaw, Ginger D; Pardo Manuel de Villena, Fernando; Baric, Ralph S; Ferris, Martin T; Valdar, William

SARS-CoV-2 infection induces pro-fibrotic and pro-thrombotic foam cell formation.

SARS-CoV-2 感染可诱导促纤维化和促血栓形成的泡沫细胞形成。

Battaglia Diana M, Post Claire E, Yao Wenbo, Wahl Angela, Gralinski Lisa E, Liu Hongwei, Dang Hong, Madden Victoria J, White Kristen K, Leist Sarah R, Dinnion Kenneth H 3rd, De la Cruz Gabriela, Midkiff Bentley R, Froggatt Heather M, Gully Kendra, Zweigart Mark, Reader J Rachel, Olstad Katherine J, Everitt Jeffrey I, Van Rompay Koen K A, De Paris Kristina, Sajti Eniko, Pickles Raymond J, Browne Edward P, Jones Corbin D, Boucher Richard C Jr, Baric Ralph S, Garcia J Victor

Mouse-adapted SARS-CoV-2 Omicron BA.5 infection induces post-acute lung fibrosis in BALB/c mice

小鼠适应性SARS-CoV-2 Omicron BA.5感染可诱导BALB/c小鼠发生急性后肺纤维化。

Powers, John M; Leist, Sarah R; Suryadevara, Naveenchandra; Zost, Seth J; Binshtein, Elad; Abdelgadir, Anfal; Mallory, Michael L; Edwards, Caitlin E; Gully, Kendra L; Hubbard, Miranda L; Zweigart, Mark R; Bailey, Alexis B; Sheahan, Timothy P; Crowe, James E Jr; Montgomery, Stephanie A; Harkema, Jack R; Baric, Ralph S

Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity

肺上皮细胞稳态和免疫失调是导致中东呼吸综合征冠状病毒疾病严重程度增加的原因之一。

Sims, Amy C; Schäfer, Alexandra; Okuda, Kenichi; Leist, Sarah R; Kocher, Jacob F; Cockrell, Adam S; Hawkins, Padraig E; Furusho, Minako; Jensen, Kara L; Kyle, Jennifer E; Burnum-Johnson, Kristin E; Stratton, Kelly G; Lamar, Natalie C; Niccora, Carrie D; Weitz, Karl K; Smith, Richard D; Metz, Thomas O; Waters, Katrina M; Boucher, Richard C; Montgomery, Stephanie A; Baric, Ralph S; Sheahan, Timothy P

IMMU-22. TGFβ inhibition and radiotherapy synergize to enable immune memory response to PD-L1 immune checkpoint inhibition in syngeneic glioblastoma mouse models

IMMU-22. TGFβ抑制剂与放射疗法协同作用,可在同源胶质母细胞瘤小鼠模型中诱导对PD-L1免疫检查点抑制剂的免疫记忆反应。

Kundu, Somanath; Mitra, Soham; Roshini, Arivazhagan; Longo, John A; Longo, Sharon L; Venskus, Abigail; Babu, Harish; Viapiano, Mariano S; Biose, Ifechukwude Joachim; Narayanappa, Amruta; Gressett, Timothy E; Leist, Sarah R; Srivastava, Akhilesh; Ismael, Saifudeen; Kolls, Jay; Baric, Ralph S; Bix, Gregory J; Popryadukhin, AY; Asaturova, AV; Arakelyan, AS; Stepanian, AA; Adamyan, LV; Silva, Jeffrey C; Dikler, Sergei; Mamaev, Sergey; Worsfold, Camilla; Moghekar, Abhay; Wiederhold, Thorsten; Hamza, Ghaith M; Wojchowski, Don M; Castaldi, M Paola; Kapur, Shirin Arastu; Bergo, Vladislav B; Chien, Allis; Martin, Roy; Weis-Garcia, Frances; Silva, Jeffrey C; Dikler, Sergei; Mamaev, Sergey; Worsfold, Camilla; Moghekar, Abhay; Wiederhold, Thorsten; Hamza, Ghaith M; Wojchowski, Don M; Castaldi, M Paola; Kapur, Shirin Arastu; Bergo, Vladislav B; Chien, Allis; Martin, Roy; Weis-Garcia, Frances; Sehu, Marjoree; Patterson, Tina; Houghton, Kate; Pharm, B; Firman, Paul; Klyza, Zack; McDougall, David; Pharm, B; Barcellos-Hoff, Mary Helen; Reiners, Oliver; Gonzalez-Junca, Alba; Lazar, Ann; Chou, William

Animal models of Long Covid: A hit-and-run disease

新冠长期症状的动物模型:一种速战速决的疾病

Schäfer, Alexandra; Leist, Sarah R; Powers, John M; Baric, Ralph S

Mapping of susceptibility loci for Ebola virus pathogenesis in mice

小鼠埃博拉病毒致病易感基因位点的定位

Schäfer, Alexandra; Marzi, Andrea; Furuyama, Wakako; Catanzaro, Nicholas J; Nguyen, Cameron; Haddock, Elaine; Feldmann, Friederike; Meade-White, Kimberly; Thomas, Tina; Hubbard, Miranda L; Gully, Kendra L; Leist, Sarah R; Hock, Pablo; Bell, Timothy A; De la Cruz, Gabriela E; Midkiff, Bentley R; Martinez, David R; Shaw, Ginger D; Miller, Darla R; Vernon, Michael J; Graham, Rachel L; Cowley, Dale O; Montgomery, Stephanie A; Schughart, Klaus; de Villena, Fernando Pardo Manuel; Wilkerson, Gregory K; Ferris, Martin T; Feldmann, Heinz; Baric, Ralph S

Host Genetic Variation Impacts SARS-CoV-2 Vaccination Response in the Diversity Outbred Mouse Population.

宿主遗传变异影响 SARS-CoV-2 疫苗在多样性近交系小鼠群体中的反应

Cruz Cisneros Marta C, Anderson Elizabeth J, Hampton Brea K, Parotti Breantié, Sarkar Sanjay, Taft-Benz Sharon, Bell Timothy A, Blanchard Matthew, Dillard Jacob A, Dinnon Kenneth H 3rd, Hock Pablo, Leist Sarah R, Madden Emily A, Shaw Ginger D, West Ande, Baric Ralph S, Baxter Victoria K, Pardo-Manuel de Villena Fernando, Heise Mark T, Ferris Martin T

Sarbecovirus disease susceptibility is conserved across viral and host models

沙贝病毒疾病易感性在病毒和宿主模型中均得以保留

Leist, Sarah R; Schäfer, Alexandra; Risemberg, Ellen L; Bell, Timothy A; Hock, Pablo; Zweigart, Mark R; Linnertz, Colton L; Miller, Darla R; Shaw, Ginger D; de Villena, Fernando Pardo Manuel; Ferris, Martin T; Valdar, William; Baric, Ralph S

Divergent pathogenetic outcomes in BALB/c mice following Omicron subvariant infection

BALB/c小鼠感染Omicron亚型病毒后出现不同的发病机制

Powers, John M; Leist, Sarah R; Mallory, Michael L; Yount, Boyd L; Gully, Kendra L; Zweigart, Mark R; Bailey, Alexis B; Sheahan, Timothy P; Harkema, Jack R; Baric, Ralph S