日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pan-cancer landscape of protein kinase D3: An integrative TCGA multi-omics analysis of clinical, molecular, and immunological roles

蛋白激酶D3在泛癌中的作用图谱:基于TCGA多组学数据的临床、分子和免疫学功能整合分析

Loaiza-Moss, Jocshan; Leitges, Michael

Prkci Regulates Autophagy and Pancreatic Tumorigenesis in Mice

Prkci 调控小鼠自噬和胰腺肿瘤发生

Inman, Kristin S; Liu, Yi; Scotti Buzhardt, Michele L; Leitges, Michael; Krishna, Murli; Crawford, Howard C; Fields, Alan P; Murray, Nicole R

Dysfunctional EGFR and oxidative stress-induced PKD1 signaling drive formation of DCLK1+ pancreatic stem cells

EGFR功能障碍和氧化应激诱导的PKD1信号通路驱动DCLK1+胰腺干细胞的形成

Fleming Martinez, Alicia K; Döppler, Heike R; Bastea, Ligia I; Edenfield, Brandy; Patel, Tushar; Leitges, Michael; Liou, Geou-Yarh; Storz, Peter

Stromal cell protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance

基质细胞蛋白激酶C-β抑制剂可增强B细胞恶性肿瘤的化疗敏感性并克服耐药性。

Park, Eugene; Chen, Jingyu; Moore, Andrew; Mangolini, Maurizio; Santoro, Antonella; Boyd, Joseph R; Schjerven, Hilde; Ecker, Veronika; Buchner, Maike; Williamson, James C; Lehner, Paul J; Gasparoli, Luca; Williams, Owen; Bloehdorn, Johannes; Stilgenbauer, Stephan; Leitges, Michael; Egle, Alexander; Schmidt-Supprian, Marc; Frietze, Seth; Ringshausen, Ingo

Loss-of-function phenotype of a PKCθ(T219A) knockin mouse strain

PKCθ(T219A)敲入小鼠品系的功能丧失表型

Thuille, Nikolaus; Siegmund, Kerstin; Klepsch, Victoria; Schörgenhuber, Jacqueline; Danklmaier, Sarah; Leitges, Michael; Baier, Gottfried

Novel mutant mouse line emphasizes the importance of protein kinase C theta for CD4(+) T lymphocyte activation.

新型突变小鼠品系强调了蛋白激酶 C θ 对 CD4(+) T 淋巴细胞活化的重要性

Siegmund Kerstin, Thuille Nikolaus, Posch Nina, Fresser Friedrich, Leitges Michael, Baier Gottfried

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling

激酶PKD3通过抑制胰岛素信号传导,对胆固醇和甘油三酯的合成提供负反馈。

Mayer, Alexander E; Löffler, Mona C; Loza Valdés, Angel E; Schmitz, Werner; El-Merahbi, Rabih; Viera, Jonathan Trujillo; Erk, Manuela; Zhang, Thianzhou; Braun, Ursula; Heikenwalder, Mathias; Leitges, Michael; Schulze, Almut; Sumara, Grzegorz

Retraction: Protein kinase C is a calcium sensor for presynaptic short-term plasticity

撤稿:蛋白激酶C是突触前短期可塑性的钙传感器

Fioravante, Diasynou; Chu, YunXiang; de Jong, Arthur Ph; Leitges, Michael; Kaeser, Pascal S; Regehr, Wade G

Control of Paneth Cell Fate, Intestinal Inflammation, and Tumorigenesis by PKCλ/ι

PKCλ/ι 调控潘氏细胞命运、肠道炎症和肿瘤发生

Nakanishi, Yuki; Reina-Campos, Miguel; Nakanishi, Naoko; Llado, Victoria; Elmen, Lisa; Peterson, Scott; Campos, Alex; De, Surya K; Leitges, Michael; Ikeuchi, Hiroki; Pellecchia, Maurizio; Blumberg, Richard S; Diaz-Meco, Maria T; Moscat, Jorge

Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions

突变型KRas诱导的腺泡细胞线粒体氧化应激上调EGFR信号通路,从而促进胰腺癌前病变的形成

Liou, Geou-Yarh; Döppler, Heike; DelGiorno, Kathleen E; Zhang, Lizhi; Leitges, Michael; Crawford, Howard C; Murphy, Michael P; Storz, Peter