日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Precancer exercise capacity and metabolism during tumor development coordinate the skeletal muscle-tumor metabolic competition

癌前运动能力和肿瘤发展过程中的代谢协调骨骼肌与肿瘤之间的代谢竞争

Leitner, Brooks P; Fosam, Andin E; Lee, Won D; Zilinger, Kaylee; Nakandakari, Susana C B R; Zhang, Xinyi; Gaspar, Rafael C; Zhu, Wanling; Perry, Curtis J; Rabinowitz, Joshua D; Perry, Rachel J

The thermoneutral zone in women takes an "arctic" shift compared to men

与男性相比,女性的热中性区发生了“北极”般的偏移。

Brychta, Robert J; McGehee, Suzanne; Huang, Shan; Leitner, Brooks P; Duckworth, Courtney J; Fletcher, Laura A; Kim, Katherine; Cassimatis, Thomas M; Israni, Nikita S; Lea, Hannah J; Lentz, Taylor N; Pierce, Anne E; Jiang, Alex; LaMunion, Samuel R; Thomas, Reed J; Ishihara, Asuka; Courville, Amber B; Yang, Shanna B; Reitman, Marc L; Cypess, Aaron M; Chen, Kong Y

Small molecule inhibition of glycogen synthase I reduces muscle glycogen content and improves biomarkers in a mouse model of Pompe disease.

小分子抑制糖原合成酶 I 可降低庞贝氏症小鼠模型的肌肉糖原含量并改善生物标志物

Gaspar Rafael Calais, Sakuma Ikki, Nasiri Ali, Hubbard Brandon T, LaMoia Traci E, Leitner Brooks P, Tep Samnang, Xi Yannan, Green Eric M, Ullman Julie C, Petersen Kitt Falk, Shulman Gerald I

The metabolic and physiologic impairments underlying long COVID associated exercise intolerance

与新冠长期症状相关的运动不耐受的代谢和生理障碍

Leitner, Brooks P; Joseph, Phillip; Quast, Andres Figueroa; Ramirez, Maria Alejandra; Heerdt, Paul M; Villalobos, Jose G; Singh, Inderjit

Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice

肌细胞内脂质的独特亚细胞定位和降低的 PKCε/PKCθ 活性可维持运动训练小鼠的肌肉胰岛素敏感性

Gaspar, Rafael C; Lyu, Kun; Hubbard, Brandon T; Leitner, Brooks P; Luukkonen, Panu K; Hirabara, Sandro M; Sakuma, Ikki; Nasiri, Ali; Zhang, Dongyan; Kahn, Mario; Cline, Gary W; Pauli, José Rodrigo; Perry, Rachel J; Petersen, Kitt F; Shulman, Gerald I

Proteomic profiling demonstrates inflammatory and endotheliopathy signatures associated with impaired cardiopulmonary exercise hemodynamic profile in Post Acute Sequelae of SARS-CoV-2 infection (PASC) syndrome

蛋白质组学分析显示,SARS-CoV-2感染后急性期综合征(PASC综合征)中存在与心肺运动血流动力学受损相关的炎症和内皮病变特征。

Singh, Inderjit; Leitner, Brooks P; Wang, Yiwei; Zhang, Hanming; Joseph, Phillip; Lutchmansingh, Denyse D; Gulati, Mridu; Possick, Jennifer D; Damsky, William; Hwa, John; Heerdt, Paul M; Chun, Hyung J

Representation of American Indian and Alaska Native Individuals in Academic Medical Training

美国印第安人和阿拉斯加原住民在学术医学培训中的代表性

Forrest, Lala L; Leitner, Brooks P; Vasquez Guzman, Cirila Estela; Brodt, Erik; Odonkor, Charles A

Multimodal analysis suggests differential immuno-metabolic crosstalk in lung squamous cell carcinoma and adenocarcinoma

多模态分析表明肺鳞状细胞癌和腺癌中存在不同的免疫代谢串扰

Leitner, Brooks P; Givechian, Kevin B; Ospanova, Shyryn; Beisenbayeva, Aray; Politi, Katerina; Perry, Rachel J

Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity

同位素示踪揭示了小鼠黑色素瘤亚型对不同底物的偏好性,这些亚型具有不同的抗肿瘤免疫力。

Zhang, Xinyi; Halberstam, Alexandra A; Zhu, Wanling; Leitner, Brooks P; Thakral, Durga; Bosenberg, Marcus W; Perry, Rachel J

Insulin and cancer: a tangled web

胰岛素与癌症:错综复杂的关系网

Leitner, Brooks P; Siebel, Stephan; Akingbesote, Ngozi D; Zhang, Xinyi; Perry, Rachel J