日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's disease

TransEuro 是一项开放标签试验,旨在研究人类胎儿腹侧中脑移植治疗中度帕金森病患者的疗效。

Barker, Roger A; Lao-Kaim, Nicholas P; Guzman, Natalie Valle; Athauda, Dilan; Bjartmarz, Hjalmar; Björklund, Anders; Church, Alistair; Cutting, Emma; Daft, Danielle; Dayal, Viswas; Dunnett, Stephen; Evans, Amy; Grealish, Shane; Hannaway, Naomi; He, Xiaoling; Hewitt, Sam; Kefalopoulou, Zinovia; Mahlknecht, Philipp; Martín-Bastida, Antonio; Farrell, Krista; Moore, Sarah; Bulstrode, Harry; Nakornchai, Tagore; Nelander-Wahlestedt, Jenny; Roupé, Linnea; Paul, Gesine; Peall, Kathryn; Rosser, Anne; Roca-Fernández, Adriana; Rowlands, Sophie; McGorrian, Anne-Marie; Scherf, Caroline; Vinh, Ngoc Nga; Roberton, Victoria; Kelly, Claire; Lelos, Mariah; Torres, Eduardo; Shires, Kate; Hills, Rachel; Williams, Debbie; Roussakis, Andreas-Antonios; Sibley, Krista; Tyers, Pamela; Wijeyekoon, Ruwani; Williams-Gray, Caroline; Foltynie, Thomas; Piccini, Paola; Morris, Robert; Lazic, Stanley E; Lindvall, Olle; Parmar, Malin; Widner, Hakan

Graft ischemia post cell transplantation to the brain: Glucose deprivation as the primary driver of rapid cell death.

脑细胞移植后移植物缺血:葡萄糖缺乏是导致细胞快速死亡的主要因素

Hakami Abrar, Rizzo Sebastiano Antonio, Bartley Oliver J M, Hills Rachel, Precious Sophie V, Ostler Timothy, Fjodorova Marija, Alghamdi Majed, Rosser Anne E, Lane Emma L, Woolley Thomas E, Lelos Mariah J, Newland Ben

Nuclear ERK1/2 signaling potentiation enhances neuroprotection and cognition via Importinα1/KPNA2

核 ERK1/2 信号增强通过 Importinα1/KPNA2 增强神经保护和认知

Marzia Indrigo #, Ilaria Morella #, Daniel Orellana, Raffaele d'Isa, Alessandro Papale, Riccardo Parra, Antonia Gurgone, Daniela Lecca, Anna Cavaccini, Cezar M Tigaret, Alfredo Cagnotto, Kimberley Jones, Simon Brooks, Gian Michele Ratto, Nicholas D Allen, Mariah J Lelos, Silvia Middei, Maurizio Gius

Acyl-Ghrelin Attenuates Neurochemical and Motor Deficits in the 6-OHDA Model of Parkinson's Disease

酰基生长素释放肽可减轻6-羟基多巴胺诱导的帕金森病模型中的神经化学和运动功能障碍

Rees, Daniel; Beynon, Amy L; Lelos, Mariah J; Smith, Gaynor A; Roberts, Luke D; Phelps, Lyndsey; Dunnett, Stephen B; Morgan, Alwena H; Brown, Rowan M; Wells, Timothy; Davies, Jeffrey S

Inhibition of 7α,26-dihydroxycholesterol biosynthesis promotes midbrain dopaminergic neuron development

抑制7α,26-二羟基胆固醇生物合成可促进中脑多巴胺能神经元发育

James Hennegan,Aled H Bryant,Lauren Griffiths ,Matthieu Trigano,Oliver J M Bartley,Joanna J Bartlett,Carys Minahan,Willy Antoni Abreu de Oliveira,Eylan Yutuc,Sotirios Ntikas,Christos S Bartsocas,Margarita Markouri,Eleni Antoniadou,Ioanna Laina,Owain W Howell,Meng Li,Yuqin Wang,William J Griffiths,Emma L Lane,Mariah J Lelos,Spyridon Theofilopoulos

Impaired cognitive and motor function are coincident with L-DOPA-induced dyskinesia in a model of Parkinson's disease

在帕金森病模型中,认知和运动功能受损与左旋多巴诱发的运动障碍同时发生

Mariah J Lelos #, Ellen M Murphy #, Hanna S Lindgren, Stephen B Dunnett, Emma L Lane

Identification of the Neural Correlates Underlying Conflict Resolution Performance Using a Rodent Analogue of the Stroop Tests

利用啮齿动物版斯特鲁普测试识别冲突解决能力背后的神经关联

Clinch, S P; Busse, M; Griffiths, J; Rosser, A E; Lelos, M J

Neurite Outgrowth and Gene Expression Profile Correlate with Efficacy of Human Induced Pluripotent Stem Cell-Derived Dopamine Neuron Grafts

神经突生长和基因表达谱与人诱导多能干细胞衍生多巴胺神经元移植的疗效相关

Hills, Rachel; Mossman, Jim A; Bratt-Leal, Andres M; Tran, Ha; Williams, Roy M; Stouffer, David G; Sokolova, Irina V; Sanna, Pietro P; Loring, Jeanne F; Lelos, Mariah J

Spontaneous Graft-Induced Dyskinesias Are Independent of 5-HT Neurons and Levodopa Priming in a Model of Parkinson's Disease

在帕金森病模型中,自发性移植物诱发的运动障碍与 5-HT 神经元和左旋多巴启动无关

Emma L Lane, David J Harrison, Elena Ramos-Varas, Rachel Hills, Sophie Turner, Mariah J Lelos

Defining the unknowns for cell therapies in Parkinson's disease

明确帕金森病细胞疗法的未知因素

Lane, Emma L; Lelos, Mariah J