日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The RavA-ViaA chaperone complex modulates bacterial persistence through its association with the fumarate reductase enzyme

RavA-ViaA分子伴侣复合物通过与延胡索酸还原酶的结合来调节细菌的持久性。

Bhandari, Vaibhav; Reichheld, Sean E; Houliston, Scott; Lemak, Alexander; Arrowsmith, Cheryl H; Sharpe, Simon; Houry, Walid A

The MLL1 trimeric catalytic complex is a dynamic conformational ensemble stabilized by multiple weak interactions

MLL1三聚体催化复合物是一个动态的构象集合体,由多个弱相互作用稳定。

Kaustov, Lilia; Lemak, Alexander; Wu, Hong; Faini, Marco; Fan, Lixin; Fang, Xianyang; Zeng, Hong; Duan, Shili; Allali-Hassani, Abdellah; Li, Fengling; Wei, Yong; Vedadi, Masoud; Aebersold, Ruedi; Wang, Yunxing; Houliston, Scott; Arrowsmith, Cheryl H

Extrachromosomal circular elements targeted by CRISPR-Cas in Dehalococcoides mccartyi are linked to mobilization of reductive dehalogenase genes

CRISPR-Cas 靶向的麦卡脱卤球菌染色体外环状元件与还原脱卤酶基因的动员有关

Olivia Molenda, Shuiquan Tang, Line Lomheim, Vasu K Gautam, Sofia Lemak, Alexander F Yakunin, Karen L Maxwell, Elizabeth A Edwards

Functional diversification of the NleG effector family in enterohemorrhagic Escherichia coli

肠出血性大肠杆菌中 NleG 效应蛋白家族的功能多样化

Valleau, Dylan; Little, Dustin J; Borek, Dominika; Skarina, Tatiana; Quaile, Andrew T; Di Leo, Rosa; Houliston, Scott; Lemak, Alexander; Arrowsmith, Cheryl H; Coombes, Brian K; Savchenko, Alexei

Global analysis of protein folding using massively parallel design, synthesis, and testing

利用大规模并行设计、合成和测试对蛋白质折叠进行全局分析

Rocklin, Gabriel J; Chidyausiku, Tamuka M; Goreshnik, Inna; Ford, Alex; Houliston, Scott; Lemak, Alexander; Carter, Lauren; Ravichandran, Rashmi; Mulligan, Vikram K; Chevalier, Aaron; Arrowsmith, Cheryl H; Baker, David

Conformational dynamics of the TTD-PHD histone reader module of the UHRF1 epigenetic regulator reveals multiple histone-binding states, allosteric regulation, and druggability

UHRF1表观遗传调控因子TTD-PHD组蛋白阅读模块的构象动力学揭示了其多种组蛋白结合状态、变构调控和成药性。

Houliston, R Scott; Lemak, Alexander; Iqbal, Aman; Ivanochko, Danton; Duan, Shili; Kaustov, Lilia; Ong, Michelle S; Fan, Lixin; Senisterra, Guillermo; Brown, Peter J; Wang, Yun-Xing; Arrowsmith, Cheryl H

Solution NMR structure of the TRIM21 B-box2 and identification of residues involved in its interaction with the RING domain

TRIM21 B-box2 的溶液核磁共振结构及其与 RING 结构域相互作用相关残基的鉴定

Wallenhammar, Amélie; Anandapadamanaban, Madhanagopal; Lemak, Alexander; Mirabello, Claudio; Lundström, Patrik; Wallner, Björn; Sunnerhagen, Maria

The second round of Critical Assessment of Automated Structure Determination of Proteins by NMR: CASD-NMR-2013

第二轮基于核磁共振的蛋白质自动结构测定关键评估:CASD-NMR-2013

Rosato, Antonio; Vranken, Wim; Fogh, Rasmus H; Ragan, Timothy J; Tejero, Roberto; Pederson, Kari; Lee, Hsiau-Wei; Prestegard, James H; Yee, Adelinda; Wu, Bin; Lemak, Alexander; Houliston, Scott; Arrowsmith, Cheryl H; Kennedy, Michael; Acton, Thomas B; Xiao, Rong; Liu, Gaohua; Montelione, Gaetano T; Vuister, Geerten W

Structural characterization of a flexible two-domain protein in solution using small angle X-ray scattering and NMR data

利用小角X射线散射和核磁共振数据对溶液中柔性双结构域蛋白进行结构表征

Lemak, Alexander; Wu, Bin; Yee, Adelinda; Houliston, Scott; Lee, Hsiau-Wei; Gutmanas, Aleksandras; Fang, Xianyang; Garcia, Maite; Semesi, Anthony; Wang, Yun-Xing; Prestegard, James H; Arrowsmith, Cheryl H

Basic Tilted Helix Bundle - a new protein fold in human FKBP25/FKBP3 and HectD1.

基本倾斜螺旋束——人类 FKBP25/FKBP3 和 HectD1 中的一种新的蛋白质折叠

Helander Sara, Montecchio Meri, Lemak Alexander, Farès Christophe, Almlöf Jonas, Yi Yanjun, Yee Adelinda, Arrowsmith Cheryl, DhePaganon Sirano, Sunnerhagen Maria