The GPR4 antagonist NE-52-QQ57 increases survival, mitigates the hyperinflammatory response and reduces viral load in SARS-CoV-2-infected K18-hACE2 transgenic mice.
GPR4 拮抗剂 NE-52-QQ57 可提高 SARS-CoV-2 感染的 K18-hACE2 转基因小鼠的存活率，减轻过度炎症反应，并降低病毒载量
期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1549296
Wu Xin-Jun, Oppelt Karen A, Fan Ming, Marie Mona A, Swyers Madison M, Williams Ashley J, Lemasson Isabelle M, Roper Rachel L, Bolin Paul, Yang Li V
