日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Anti-amyloid antibody equilibrium binding to Aβ aggregates from human Alzheimer's disease brain

抗淀粉样蛋白抗体与来自人类阿尔茨海默病脑组织的Aβ聚集体的平衡结合

Bjørnholm, Katrine D; Butler, P Monroe; Francis, Anna E; Varma, Curran; Spooner, Emma T; Grenon, Martine B; Xu, Yi Ran; Tao, Youqi; Meunier, Angela L; Anderson, Amirah K; Hennessey, Elizabeth L; Miller, Michael B; Selkoe, Dennis J; Lemere, Cynthia A; Stern, Andrew M

Amyloid-related imaging abnormalities (ARIA) in anti-amyloid therapies for Alzheimer's disease: An update from the Alzheimer's Association ARIA workgroup

阿尔茨海默病抗淀粉样蛋白疗法中淀粉样蛋白相关影像异常(ARIA):阿尔茨海默病协会ARIA工作组的最新进展

van Etten, Ellis S; Mahinrad, Simin; Grill, Joshua D; Salloway, Stephen; Atri, Alireza; Cogswell, Petrice M; Benzinger, Tammie L S; Iwatsubo, Takeshi; Iadecola, Costantino; Lemere, Cynthia A; Nicoll, James A R; Greenberg, Steven M; Carrillo, Maria C; Jack, Clifford R Jr; Sperling, Reisa A

C3 lowering in adult APP KI mice rescues synapses and spares cognitive decline

降低成年APP KI小鼠体内C3水平可挽救突触并延缓认知衰退

Singh, Brijendra; Batista, Andre F; Spooner, Emma T; Colletti, Brianna R; Saido, Takaomi C; Carroll, Michael C; Lemere, Cynthia A

Early Binding of Anti-Amyloid Antibodies to CAA Drives Complement Activation, Inflammation and ARIA in Mice.

抗淀粉样蛋白抗体与 CAA 的早期结合可驱动小鼠体内的补体激活、炎症和 ARIA。

Bathini Praveen, Schilling Stephan, Rahfeld Jens-Ulrich, Holtzman David M, Saido Takaomi C, Lemere Cynthia A

The complement cascade in Alzheimer's disease: modern implications of an ancient immune protagonist

阿尔茨海默病中的补体级联反应:古老免疫主角的现代意义

Papavergi, Maria-Tzousi; Bathini, Praveen; Singh, Brijendra; Lemere, Cynthia A

CAA proteomics meta-analysis reveals novel targets, key players, and the effects of sex, APOE, and brain region in humans

CAA蛋白质组学荟萃分析揭示了人类CAA的新靶点、关键参与者以及性别、APOE基因型和脑区的影响

Varma, Curran; Lemere, Cynthia A

Target Validation Studies of PS48, a PDK-1 Allosteric Agonist, for the Treatment of Alzheimer's Disease Phenotype in APP/PS1 Transgenic Mice.

PS48(一种 PDK-1 变构激动剂)在 APP/PS1 转基因小鼠中治疗阿尔茨海默病表型的靶点验证研究

Querfurth Henry W, Lemere Cynthia, Ciola Jason, Havas Daniel, Xia Weiming, Lee Han Kyu

Differential Vascular and Non‐Vascular Binding Patterns of ACU193 and R‐Lecanemab in APP;hAPOE4 Mouse Brain Sections

ACU193 和 R-Lecanemab 在 APP;hAPOE4 小鼠脑切片中的血管和非血管结合模式差异

Agis-Balboa, Roberto Carlos; Guidotti, Alessandro; Pinna, Graziano; Grenon, Martine B; Cline, Erika N; Jerecic, Jasna; Johnson, Elizabeth; Siemers, Eric; Lemere, Cynthia A

Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference

免疫学与痴呆症研究进展:2023 年 AAIC 免疫学进展大会亮点

Kloske, Courtney M; Mahinrad, Simin; Barnum, Christopher J; Batista, Andre F; Bradshaw, Elizabeth M; Butts, Brittany; Carrillo, Maria C; Chakrabarty, Paramita; Chen, Xiaoying; Craft, Suzanne; Da Mesquita, Sandro; Dabin, Luke C; Devanand, Davangere; Duran-Laforet, Violeta; Elyaman, Wassim; Evans, Elizabeth E; Fitzgerald-Bocarsly, Patricia; Foley, Kate E; Harms, Ashley S; Heneka, Michael T; Hong, Soyon; Huang, Yu-Wen A; Jackvony, Stephanie; Lai, Laijun; Guen, Yann Le; Lemere, Cynthia A; Liddelow, Shane A; Martin-Peña, Alfonso; Orr, Anna G; Quintana, Francisco J; Ramey, Grace D; Rexach, Jessica E; Rizzo, Stacey J S; Sexton, Claire; Tang, Alice S; Torrellas, Jose G; Tsai, Andy P; van Olst, Lynn; Walker, Keenan A; Wharton, Whitney; Tansey, Malú Gámez; Wilcock, Donna M

Global C3 lowering in adulthood protects against hippocampal dysfunction and cognitive impairment in aged mice.

成年期降低全身 C3 水平可以保护老年小鼠免受海马功能障碍和认知障碍的影响

Batista Andre F, Presumey Jessey, Singh Brijendra, Schroeder Maren K, Khan Khyrul, Spooner Emma, Li Shaomin, Carroll Michael C, Lemere Cynthia A