日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A broad-spectrum pneumococcal vaccine induces mucosal immunity and protects against lethal Streptococcus pneumoniae challenge

广谱肺炎球菌疫苗可诱导黏膜免疫，并能抵御致命的肺炎链球菌感染。

期刊:Emerging Microbes & Infections
影响因子:7.5
doi:10.1080/22221751.2023.2272656
Chiu, Fang-Feng; Tu, Ling-Ling; Chen, Wangxue; Zhou, Hongyan; Liu, Bing-Sin; Liu, Shih-Jen; Leng, Chih-Hsiang
肺炎
炎症/感染
免疫/内分泌
发表日期：2023
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Truncated Pneumolysin from Streptococcus pneumoniae as a TLR4-Antagonizing New Drug for Chronic Inflammatory Conditions

肺炎链球菌截短型肺炎溶素作为一种TLR4拮抗剂，可用于治疗慢性炎症性疾病

期刊:Cells
影响因子:5.2
doi:10.3390/cells9051183
Chang, Shun-Fu; Chen, Cheng-Nan; Lin, Jung-Chung; Wang, Hsin-Ell; Mori, Shigetarou; Li, Jia-Je; Yen, Chia-Kuang; Hsu, Ching-Yun; Fung, Chang-Phone; Chong, Pele Choi-Sing; Leng, Chih-Hsiang; Ding, Yi-Jun; Chang, Feng-Yee; Siu, L Kristopher
肺炎
TLR4
炎症/感染
炎症
发表日期：2020
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Efficient Uptake of Recombinant Lipidated Survivin by Antigen-Presenting Cells Initiates Antigen Cross-Presentation and Antitumor Immunity

抗原呈递细胞对重组脂化Survivin的有效摄取启动抗原交叉呈递和抗肿瘤免疫

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2018.00822
Chiang, Chen-Yi; Chen, Yi-Jyun; Wu, Chiao-Chieh; Liu, Shih-Jen; Leng, Chih-Hsiang; Chen, Hsin-Wei
肿瘤
肿瘤免疫
Survivin
细胞生物学
免疫/内分泌
发表日期：2018
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Identification of Immunoreactive Peptides of Toxins to Simultaneously Assess the Neutralization Potency of Antivenoms against Neurotoxicity and Cytotoxicity of Naja atra Venom

鉴定毒素的免疫反应肽，以同时评估抗蛇毒血清对眼镜蛇毒液神经毒性和细胞毒性的中和效力

期刊:Toxins
影响因子:4
doi:10.3390/toxins10010010
Liu, Bin-Sin; Wu, Wen-Guey; Lin, Min-Han; Li, Chi-Han; Jiang, Bo-Rong; Wu, Suh-Chin; Leng, Chih-Hsiang; Sung, Wang-Chou
毒理研究
细胞生物学
免疫/内分泌
发表日期：2017
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CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses

针对石斑鱼 Toll 样受体 (TLR) 21 开发的 CpG 寡脱氧核苷酸可有效激活小鼠和人 TLR9 介导的免疫反应。

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-017-17609-2
Yeh, Da-Wei; Lai, Chao-Yang; Liu, Yi-Ling; Lu, Chih-Hao; Tseng, Ping-Hui; Yuh, Chiou-Hwa; Yu, Guann-Yi; Liu, Shih-Jen; Leng, Chih-Hsiang; Chuang, Tsung-Hsien
信号转导
TLR9
免疫/内分泌
发表日期：2017
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Immunogenicity of a novel tetravalent vaccine formulation with four recombinant lipidated dengue envelope protein domain IIIs in mice

一种新型四价疫苗制剂（含四种重组脂化登革热包膜蛋白结构域III）在小鼠体内的免疫原性

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/srep30648
Chiang, Chen-Yi; Pan, Chien-Hsiung; Chen, Mei-Yu; Hsieh, Chun-Hsiang; Tsai, Jy-Ping; Liu, Hsueh-Hung; Liu, Shih-Jen; Chong, Pele; Leng, Chih-Hsiang; Chen, Hsin-Wei
微生物学
登革热
免疫/内分泌
发表日期：2016
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The successful induction of T-cell and antibody responses by a recombinant measles virus-vectored tetravalent dengue vaccine provides partial protection against dengue-2 infection

利用重组麻疹病毒载体的四价登革热疫苗成功诱导T细胞和抗体反应，可提供针对登革热2型病毒感染的部分保护。

期刊:Human Vaccines & Immunotherapeutics
影响因子:3.5
doi:10.1080/21645515.2016.1143576
Hu, Hui-Mei; Chen, Hsin-Wei; Hsiao, Yu-Ju; Wu, Szu-Hsien; Chung, Han-Hsuan; Hsieh, Chun-Hsiang; Chong, Pele; Leng, Chih-Hsiang; Pan, Chien-Hsiung
T细胞
炎症/感染
微生物学
T细胞
麻疹
细胞生物学
登革热
免疫/内分泌
发表日期：2016
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Recombinant lipoprotein-based vaccine candidates against C. difficile infections

针对艰难梭菌感染的重组脂蛋白疫苗候选药物

期刊:Journal of Biomedical Science
影响因子:12.1
doi:10.1186/s12929-015-0171-x
Huang, Jui-Hsin; Wu, Chia-Wei; Lien, Shu-Pei; Leng, Chih-Hsiang; Hsiao, Kuang-Nan; Liu, Shih-Jen; Chen, Hsin-Wei; Siu, Leung-Kei; Chong, Pele
炎症/感染
发表日期：2015
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Biochemical and Immunological Characterization of Truncated Fragments of the Receptor-Binding Domains of C. difficile Toxin A

艰难梭菌毒素A受体结合域截短片段的生化和免疫学特征

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0135045
Huang, Jui-Hsin; Shen, Zhe-Qing; Lien, Shu-Pei; Hsiao, Kuang-Nan; Leng, Chih-Hsiang; Chen, Chi-Chang; Siu, Leung-Kei; Chong, Pele Choi-Sing
信号转导
免疫/内分泌
发表日期：2015
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The Immunodominance Change and Protection of CD4+ T-Cell Responses Elicited by an Envelope Protein Domain III-Based Tetravalent Dengue Vaccine in Mice

基于包膜蛋白结构域III的四价登革热疫苗在小鼠体内诱导的免疫优势变化和CD4+ T细胞反应的保护作用

期刊:PLoS One
影响因子:2.6
doi:10.1371/journal.pone.0145717
Chen, Hsin-Wei; Hu, Hui-Mei; Wu, Szu-Hsien; Chiang, Chen-Yi; Hsiao, Yu-Ju; Wu, Chia-Kai; Hsieh, Chun-Hsiang; Chung, Han-Hsuan; Chong, Pele; Leng, Chih-Hsiang; Pan, Chien-Hsiung
T细胞
微生物学
T细胞
细胞生物学
登革热
CD4
免疫/内分泌
发表日期：2015
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