Residues 240-250 in the C-terminus of the Pirh2 protein complement the function of the RING domain in self-ubiquitination of the Pirh2 protein.

Pirh2 蛋白 C 端第 240-250 位残基与 RING 结构域互补，共同实现 Pirh2 蛋白的自我泛素化