日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An Epigenetic Basis for Sustained Inflammatory Epithelial Progenitor Cell States in Crohn's Disease.

克罗恩病中持续性炎症上皮祖细胞状态的表观遗传学基础。

Karakasheva Tatiana A, Martinez Clara Morral, Zhou Yusen, Qui Jingya, Chen Xinyi E, Soto Gloria E, Nettleford Shaneice K, Hix Olivia T, Roach Daana M, Laguerta Alyssa M, Thadi Anusha, Edwards Rachael M, Aleynick Daniel, Weinbrom Sarah, Borodyanskaya Elizaveta, Pickering Oliver H, Fulton MaryKate, Chen Chia-Hui, Peterson Isabella V, Hagen Erik B, Yannuzzi Ian P, Haider Zainab, Cramer Zvi, Conrad Maire A, Li Ning, Bewtra Meenakshi, Uzun Yasin, Tan Kai, Kelsen Judith R, Minn Andy J, Lengner Christopher J, Hamilton Kathryn E

APC coordinates GSK3 phosphorylation of SETD8 to suppress colorectal cancer

APC 协调 GSK3 对 SETD8 的磷酸化以抑制结直肠癌

Cramer, Zvi; Monaghan, Keara; Petroni, Ricardo; Wang, Xin; Adams-Tzivelekidis, Stephanie; Durning, Kayla; Kim, Melissa S; Tian, Yuhua; Johnson, Nicolette M; Carrera Rodríguez, María F; Gao, Xiaoyuan; Leu, Nicolae A; Sidoli, Simone; Li, Ning O; Blanco, M Andres; Lengner, Christopher J

LIN28B-mediated PI3K/AKT pathway activation promotes metastasis in colorectal cancer models.

LIN28B介导的PI3K/AKT通路激活促进结直肠癌模型中的转移

Shin Alice E, Sugiura Kensuke, Kariuki Secunda W, Cohen David A, Flashner Samuel P, Klein-Szanto Andres J, Nishiwaki Noriyuki, De Dechokyab, Vasan Neil, Gabre Joel T, Lengner Christopher J, Sims Peter A, Rustgi Anil K

Forward genetic screening in engineered colorectal cancer organoids identifies regulators of metastasis

利用工程化结直肠癌类器官进行正向基因筛选,鉴定出转移调控因子

Wang, Xin; Cramer, Zvi; Leu, Nicolae Adrian; Monaghan, Keara; Durning, Kayla; Adams-Tzivelekidis, Stephanie; Rhoades, Joshua H; Heintz, Jonathan; Tian, Yuhua; Rico, Joshua; Mendez, Diego; Petroni, Ricardo; King, Austin C; Kim, Melissa S; Matsuda, Rina; Hanselman, Olivia; Shin, Alice E; Carrera Rodríguez, María F; Brodsky, Igor E; Rustgi, Anil; Li, Ning; Lengner, Christopher J; Andrés Blanco, M

Tissue-Specific and NF-kappaB-Independent Xist RNA Localization Patterns in Female Intestinal, Blood, and Muscle Progenitors

雌性肠道、血液和肌肉祖细胞中组织特异性和NF-κB非依赖性的Xist RNA定位模式

Lovell, Claudia D; Sierra, Isabel; Welter, Emma M; Sandoval-Heglund, Donavon; Li, Ning; Vanderbeck, Ashley; Lengner, Christopher J; Lepper, Christoph; Anguera, Montserrat C

MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk

林奇综合征中MAIT细胞的富集与免疫监视和结直肠癌风险相关。

Yang, Hairu; Dungan, Michaela; Beyries, Keely; Wang, Xin; Kilpatrick, Robert; Chen, Baron; Oh, Sangmi; Berkowitz, Marissa; Smith, David; Koralov, Sergei B; Axelrad, Jordan; Lengner, Christopher J; Belle, Nicole; Bewtra, Meenakshi; Katona, Bryson W; Cadwell, Ken

Early Inflammation and Interferon Signaling Direct Enhanced Intestinal Crypt Regeneration after Proton FLASH Radiotherapy

早期炎症和干扰素信号传导促进质子FLASH放射治疗后肠隐窝再生

Lim, Tristan L; Morral, Clara; Verginadis, Ioannis I; Kim, Kyle; Luo, Leo; Foley, Caitlin J; Kim, Michele M; Li, Ning; Yoshor, Benjamin; Njah, Kizito; Putt, Mary; Oliaei Motlagh, Seyyedeh Azar; Velalopoulou, Anastasia; Chowdhury, Priyanka; Bicher, Sandra; Goia, Denisa; Lengner, Christopher J; Wrana, Jeffery L; Koumenis, Constantinos; Minn, Andy J

APC and P53 mutations synergise to create a therapeutic vulnerability to NOTUM inhibition in advanced colorectal cancer

APC 和 P53 突变协同作用,使晚期结直肠癌对 NOTUM 抑制剂产生治疗敏感性。

Tian, Yuhua; Wang, Xin; Cramer, Zvi; Rhoades, Joshua; Estep, Katrina N; Ma, Xianghui; Adams-Tzivelekidis, Stephanie; Katona, Bryson W; Johnson, F Brad; Yu, Zhengquan; Blanco, M Andres; Lengner, Christopher J; Li, Ning

High autophagic vesicle content marks facultative stem cells of the gut

肠道兼性干细胞以高自噬囊泡含量为特征。

Parham, Louis R; Johnson, Nicolette M; Lengner, Christopher J; Hamilton, Kathryn E

The Tumor Suppressor Adenomatous Polyposis Coli (apc) Is Required for Neural Crest-Dependent Craniofacial Development in Zebrafish

肿瘤抑制基因腺瘤性息肉病基因(apc)是斑马鱼神经嵴依赖性颅面发育所必需的

Liu, Xiaolei; Jones, William D; Quesnel-Vallières, Mathieu; Devadiga, Sudhish A; Lorent, Kristin; Valvezan, Alexander J; Myers, Rebecca L; Li, Ning; Lengner, Christopher J; Barash, Yoseph; Pack, Michael; Klein, Peter S