2072. Of Mice and Men: HIV-induced CD38 expression on CD8+ T lymphocytes contributes to mitochondrial dysfunction and chronic inflammation despite antiretroviral therapy
2072.《人鼠之间》：尽管接受抗逆转录病毒治疗，HIV 诱导的 CD8+ T 淋巴细胞上 CD38 的表达仍会导致线粒体功能障碍和慢性炎症
期刊:New England Journal of Medicine
影响因子:78.5
doi:10.1056/NEJMoa2201048
Palefsky, Joel M; Lee, Jeannette Y; Jay, Naomi; Goldstone, Stephen E; Darragh, Teresa M; Dunlevy, Hillary A; Rosa-Cunha, Isabella; Arons, Abigail; Pugliese, Julia C; Vena, Don; Sparano, Joseph A; Wilkin, Timothy J; Bucher, Gary; Stier, Elizabeth A; Tirado Gomez, Maribel; Flowers, Lisa; Barroso, Luis F; Mitsuyasu, Ronald T; Lensing, Shelly Y; Logan, Jeffrey; Aboulafia, David M; Schouten, Jeffrey T; de la Ossa, Juan; Levine, Rebecca; Korman, Jessica D; Hagensee, Michael; Atkinson, Thomas M; Einstein, Mark H; Cracchiolo, Bernadette M; Wiley, Dorothy; Ellsworth, Grant B; Brickman, Cristina; Berry-Lawhorn, J Michael; Mathur, Poonam; Kottilil, Shyam; Heredia, Alonso; Ghosh, Alip; Atkinson, Ben
炎症
T细胞
HIV
炎症/感染
CD8
微生物学
CD3
线粒体
CD38
细胞生物学
