Lenz H-J相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Phase II randomised study of magrolimab combined with bevacizumab-FOLFIRI in patients with previously treated advanced inoperable metastatic colorectal cancer

一项针对既往接受过治疗的晚期不可切除转移性结直肠癌患者的 II 期随机研究，评估了 magrolimab 联合贝伐单抗-FOLFIRI 方案的疗效。

doi:10.1016/j.esmogo.2026.100324

Fakih, M; Gill, S; Sampat, K; Chan, D L; Fisher, G; Cruz-Correa, M; Lenz, H-J; Garcia-Alfonso, P; Forget, F; Lonardi, S; Krauss, J; Chen, E; Cubillo Gracian, A; Liu, Y; van Buuren, N; Shao, J; Dong, M; Chen, A; Tejani, M; Hecht, J R

发表日期：2026

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Assessment of MYC Gene and WNT Pathway Alterations in Early-Onset Colorectal Cancer Among Hispanic/Latino Patients Using Integrated Multi-Omics Approaches

利用整合多组学方法评估西班牙裔/拉丁裔患者早发性结直肠癌中MYC基因和WNT通路改变

doi:10.1101/2024.12.05.24318588

Carranza, F G; Waldrup, B; Jin, Y; Amzaleg, Y; Postel, M; Craig, D W; Carpten, J D; Salhia, B; Hernandez, D; Gutierrez, N; Ricker, C N; Culver, J O; Chavez, C E; Stern, M C; Baezconde-Garbanati, L; Lenz, H J; Velazquez-Villarreal, E

发表日期：2025

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A phase I dose-escalation study of LRP5/6 antagonist BI 905677 in patients with advanced solid tumors

一项针对晚期实体瘤患者的 LRP5/6 拮抗剂 BI 905677 的 I 期剂量递增研究

期刊:ESMO Open

影响因子:8.3

doi:10.1016/j.esmoop.2024.103729

Lenz, H-J; Argilés, G; de Jonge, M J A; Yaeger, R; Doi, T; El-Khoueiry, A; Eskens, F; Kuboki, Y; Bertulis, J; Nazabadioko, S; Pronk, L; Tabernero, J

发表日期：2024

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Integrative multi-omics profiling of colorectal cancer from a Hispanic/Latino cohort of patients

对西班牙裔/拉丁裔患者队列的结直肠癌进行整合多组学分析

doi:10.1101/2024.11.03.24316599

Waldrup, B; Carranza, F; Jin, Y; Amzaleg, Y; Postel, M; Craig, D W; Carpten, J D; Salhia, B; Ricker, C N; Culver, J O; Chavez, C E; Stern, M C; Baezconde-Garbanati, L; Lenz, H J; Velazquez-Villarreal, E I

发表日期：2024

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Exploring the differences in the tumor microenvironment and immuno-oncologic targets in pancreatic ductal adenocarcinomas (PDAC) according to KRAS mutational status

根据KRAS突变状态探讨胰腺导管腺癌（PDAC）肿瘤微环境和免疫肿瘤靶点的差异

doi:10.1016/j.esmogo.2024.100042

Faber, E B; Baca, Y; Xiu, J; Walker, P; Manji, G; Gholami, S; Saeed, A; Prakash, A; Botta, G P; Sohal, D; Lenz, H J; Shields, A F; Nabhan, C; El-Deiry, W; Seeber, A; Chiu, V; Hwang, J; Lou, E

肿瘤微环境

免疫/内分泌

发表日期：2024

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Dynamic changes in RAS gene status in circulating tumour DNA: a phase II trial of first-line FOLFOXIRI plus bevacizumab for RAS-mutant metastatic colorectal cancer (JACCRO CC-11)

循环肿瘤 DNA 中 RAS 基因状态的动态变化：一线 FOLFOXIRI 联合贝伐单抗治疗 RAS 突变转移性结直肠癌的 II 期试验 (JACCRO CC-11)

期刊:ESMO Open

影响因子:8.3

doi:10.1016/j.esmoop.2022.100512

Sunakawa, Y; Satake, H; Usher, J; Jaimes, Y; Miyamoto, Y; Nakamura, M; Kataoka, M; Shiozawa, M; Takagane, A; Terazawa, T; Watanabe, T; Ishiguro, K; Tanaka, C; Takeuchi, M; Fujii, M; Danenberg, K; Danenberg, P V; Lenz, H-J; Sekikawa, T; Ichikawa, W

发表日期：2022

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PSY6-4 Regulatory aspect of regional collaboration for medical products development in Asia

PSY6-4 亚洲医疗产品开发区域合作的监管方面

期刊:Annals of Oncology

影响因子:65.4

doi:10.1093/annonc/mdr445

Labonte, M J; Wilson, P M; Yang, D; Zhang, W; Ladner, R D; Ning, Y; Gerger, A; Bohanes, P O; Benhaim, L; El-Khoueiry, R; El-Khoueiry, A; Lenz, H-J; Tsuchiya, Masami; Peters, Solange; Koga, Daisuke

发表日期：2021

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Neutropenia and survival outcomes in metastatic colorectal cancer patients treated with trifluridine/tipiracil in the RECOURSE and J003 trials

RECOURSE 和 J003 试验中，接受三氟尿苷/替吡嘧啶治疗的转移性结直肠癌患者的中性粒细胞减少症和生存结局

期刊:Annals of Oncology

影响因子:65.4

doi:10.1016/j.annonc.2019.10.005

Yoshino, T; Cleary, J M; Van Cutsem, E; Mayer, R J; Ohtsu, A; Shinozaki, E; Falcone, A; Yamazaki, K; Nishina, T; Garcia-Carbonero, R; Komatsu, Y; Baba, H; Argilés, G; Tsuji, A; Sobrero, A; Yamaguchi, K; Peeters, M; Muro, K; Zaniboni, A; Sugimoto, N; Shimada, Y; Tsuji, Y; Hochster, H S; Moriwaki, T; Tran, B; Esaki, T; Hamada, C; Tanase, T; Benedetti, F; Makris, L; Yamashita, F; Lenz, H-J

中性粒细胞

细胞生物学

发表日期：2020

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Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial

FIRE3 (AIO KRK-0306) 试验中结直肠癌 (CRC) 的共识分子亚组 (CMS) 和 FOLFIRI 联合西妥昔单抗或贝伐珠单抗一线治疗的疗效

期刊:Annals of Oncology

影响因子:65.4

doi:10.1093/annonc/mdz387

Stintzing, S; Wirapati, P; Lenz, H-J; Neureiter, D; Fischer von Weikersthal, L; Decker, T; Kiani, A; Kaiser, F; Al-Batran, S; Heintges, T; Lerchenmüller, C; Kahl, C; Seipelt, G; Kullmann, F; Moehler, M; Scheithauer, W; Held, S; Modest, D P; Jung, A; Kirchner, T; Aderka, D; Tejpar, S; Heinemann, V

多发性硬化症

发表日期：2019

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Nintedanib for the treatment of patients with refractory metastatic colorectal cancer (LUME-Colon 1): a phase III, international, randomized, placebo-controlled study

尼达尼布治疗难治性转移性结直肠癌患者（LUME-Colon 1）：一项 III 期、国际性、随机、安慰剂对照研究

期刊:Annals of Oncology

影响因子:65.4

doi:10.1093/annonc/mdy241

Van Cutsem, E; Yoshino, T; Lenz, H J; Lonardi, S; Falcone, A; Limón, M L; Saunders, M; Sobrero, A; Park, Y S; Ferreiro, R; Hong, Y S; Tomasek, J; Taniguchi, H; Ciardiello, F; Stoehr, J; Oum'Hamed, Z; Vlassak, S; Studeny, M; Argiles, G

发表日期：2018

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