A proof of concept phase I/II pilot trial of LSD1 inhibition by tranylcypromine combined with ATRA in refractory/relapsed AML patients not eligible for intensive therapy
一项概念验证 I/II 期试点试验,研究反苯环丙胺联合 ATRA 对无法接受强化治疗的难治性/复发性 AML 患者进行 LSD1 抑制
期刊:Leukemia
影响因子:12.8
doi:10.1038/s41375-020-0892-z
Maxi Wass, Stefanie Göllner, Birgit Besenbeck, Richard F Schlenk, Petra Mundmann, Joachim R Göthert, Richard Noppeney, Christoph Schliemann, Jan-Henrik Mikesch, Georg Lenz, Martin Dugas, Martin Wermke, Christoph Röllig, Martin Bornhäuser, Hubert Serve, Uwe Platzbecker, Kathrin I Foerster, Jürgen Bur