日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of proteins influencing CRISPR-associated transposases for enhanced genome editing

鉴定影响 CRISPR 相关转座酶的蛋白质以增强基因组编辑

Song, Leo C T; Alker, Amanda T P; Oromí-Bosch, Agnès; Swartz, Sophia E; Martinson, Jonathan N V; Arora, Jigyasa; Wang, Abby M; Rovinsky, Rachel; Smith, Sara J; Pierce, Emily C; Deutschbauer, Adam M; Doudna, Jennifer A; Cress, Brady F; Rubin, Benjamin E

Mechanistic insights into lenacapavir-induced off-pathway HIV-1 capsid assembly

对lenacapavir诱导的非正常HIV-1衣壳组装的机制研究

Gupta, Manish; Waltmann, Curt; Renner, Nadine; Wang, Yihang; James, Leo C; Jacques, David A; Böcking, Till; Voth, Gregory A

An inter-subunit path is required for entropically-driven and negatively cooperative binding of cyclic nucleotides in the HCN2 channel

HCN2通道中环核苷酸的熵驱动和负协同结合需要亚基间通路。

Costa, Flavio; Ng, Leo C T; Chow, Sarah S; Van Petegem, Filip; Accili, Eric A

Vaccine-induced antibodies can limit Salmonella infection in the absence of complement or macrophages

疫苗诱导产生的抗体可以在没有补体或巨噬细胞的情况下限制沙门氏菌感染。

Perez-Toledo, Marisol; Aksu-Istil, Kubra; Marcial-Juarez, Edith; Persaud, Ruby R; Alshayea, Areej; Jossi, Sian E; Carestia, Agostina; von Meijenfeld, Fien; Botto, Marina; James, Leo C; Surewaard, Bas; Afzal, Zaheer; Shields, Adrian M; Horsnell, William G; Lopez-Macias, Constantino; Henderson, Ian R; Jenne, Craig N; Cunningham, Adam F

Mitigating age-related stereo decline with perceptual training

利用感知训练缓解与年龄相关的立体视觉衰退

Kam, Ka Yee; Ng, Leo C H; Chang, Dorita H F

Low-Dose Systemic Thrombolysis as Rescue Therapy After Catheter-Directed Thrombectomy for High-Risk Pulmonary Embolism on VA-ECMO

低剂量全身溶栓作为导管血栓切除术后高危肺栓塞患者体外膜肺氧合(VA-ECMO)治疗的挽救性治疗

Nehete, Shamali; Kothari, Aditi; Mercer, Leo C; Jamal, Abdur R; Nickel, Nils P

Four doses of coronavirus disease 2019 vaccination for patients with inborn errors of immunity compared to 3 doses for healthy individuals

先天性免疫缺陷患者需接种四剂新冠病毒疫苗,而健康人群只需接种三剂。

Chan, Jeffery C H; Cheng, Samuel M S; Leung, Daniel; Wang, Xiwei; Wang, Manni; Cheuk, Yin Celeste; Ho, Cyrus; Tsang, Leo C H; Kwan, Tsz Chun; Lee, Amos M T; Li, Wing Yan; Lam, Jennifer H Y; Zhang, Kaiyue; Tam, Issan Y S; Chan, Sau Man; Chan, Koon Wing; Peiris, Malik; Tu, Wenwei; Lau, Yu Lung; Rosa Duque, Jaime S

The host protein cyclophilin A restricts nuclear entry of HIV-1 mutants by reducing the elasticity of the viral capsid

宿主蛋白环孢亲和素A通过降低病毒衣壳的弹性来限制HIV-1突变体进入细胞核。

Hong, Jun; Deshpande, Akshay; Thakare, Yatish; Simonovsky, Lora; Douglas, AidanDarian W; Guinness, Conall Mc; Rotem-Dai, Noa; Kortyna, Michelle L; Klarhof, J Ole; Shi, Jiong; James, Leo C; Boecking, Till; Francis, Ashwanth C; Rousso, Itay; Aiken, Christopher

UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains.

UbiREAD 可破译同型和分支型 K48 和 K63 泛素链的蛋白酶体降解密码

Kiss Leo, James Leo C, Schulman Brenda A

Author Correction: A substrate binding model for the KEOPS tRNA modifying complex

作者更正:KEOPS tRNA修饰复合物的底物结合模型

Beenstock, Jonah; Ona, Samara Mishelle; Porat, Jennifer; Orlicky, Stephen; Wan, Leo C K; Ceccarelli, Derek F; Maisonneuve, Pierre; Szilard, Rachel K; Yin, Zhe; Setiaputra, Dheva; Mao, Daniel Y L; Khan, Morgan; Raval, Shaunak; Schriemer, David C; Bayfield, Mark A; Durocher, Daniel; Sicheri, Frank