The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis
CSF-1 受体抑制剂 JNJ-40346527 (PRV-6527) 减少了炎症巨噬细胞向肠粘膜的募集，并抑制了小鼠 T 细胞介导的结肠炎
期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0223918
Carl L Manthey, Beverley A Moore, Yanqing Chen, Matthew J Loza, Xiang Yao, Hao Liu, Stanley M Belkowski, Holly Raymond-Parks, Paul J Dunford, Francisco Leon, Jennifer E Towne, Scott E Plevy
免疫
细胞生物学
肠炎
巨噬细胞
T Cell Receptor
