日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor

PHLPP2 是一种假磷酸酶,在后生动物祖先中失去了活性。

Husremović, Tarik; Meier, Vanessa; Piëch, Lucas; Siess, Katharina M; Antonioli, Sumire; Grishkovskaya, Irina; Kircheva, Nikoleta; Angelova, Silvia E; Wenzl, Karoline; Brandstätter, Andreas; Veis, Jiri; Miočić-Stošić, Fran; Anrather, Dorothea; Hartl, Markus; Truebestein, Linda; Cerron-Alvan, Luis M; Leeb, Martin; Žagrović, Bojan; Hann, Stephan; Bock, Christoph; Ogris, Egon; Dudev, Todor; Irwin, Nicholas A T; Haselbach, David; Leonard, Thomas A

PKD autoinhibition in trans regulates activation loop autophosphorylation in cis

PKD反式自身抑制调节顺式激活环自身磷酸化

Reinhardt, Ronja; Hirzel, Kai; Link, Gisela; Eisler, Stephan A; Hägele, Tanja; Parson, Matthew A H; Burke, John E; Hausser, Angelika; Leonard, Thomas A

A critical evaluation of protein kinase regulation by activation loop autophosphorylation

对激活环自磷酸化调控蛋白激酶的批判性评价

Reinhardt, Ronja; Leonard, Thomas A

Environment-dependent fitness gains can be driven by horizontal gene transfer of transporter-encoding genes

环境依赖的适应度增益可以通过转运蛋白编码基因的水平基因转移来驱动

David S Milner, Victoria Attah, Emily Cook, Finlay Maguire, Fiona R Savory, Mark Morrison, Carolin A Müller, Peter G Foster, Nicholas J Talbot, Guy Leonard, Thomas A Richards

Reply to Agarwal: Activity against nuclear substrates is not necessarily mediated by nuclear Akt

回复 Agarwal:针对核底物的活性不一定是由核 Akt 介导的。

Leonard, Thomas A

Conformational sampling of membranes by Akt controls its activation and inactivation

Akt通过对膜的构象采样来控制其激活和失活。

Lučić, Iva; Rathinaswamy, Manoj K; Truebestein, Linda; Hamelin, David J; Burke, John E; Leonard, Thomas A

Coiled-coils: The long and short of it

螺旋线圈:长短概述

Truebestein, Linda; Leonard, Thomas A

A molecular ruler regulates cytoskeletal remodelling by the Rho kinases.

Rho激酶作为分子尺调节细胞骨架重塑

Truebestein Linda, Elsner Daniel J, Fuchs Elisabeth, Leonard Thomas A

Crystal structure and allosteric activation of protein kinase C βII.

蛋白激酶 C βII 的晶体结构和变构激活

Leonard Thomas A, Różycki Bartosz, Saidi Layla F, Hummer Gerhard, Hurley James H

Features critical for membrane binding revealed by DivIVA crystal structure.

DivIVA晶体结构揭示了膜结合的关键特征

Oliva Maria A, Halbedel Sven, Freund Stefan M, Dutow Pavel, Leonard Thomas A, Veprintsev Dmitry B, Hamoen Leendert W, Löwe Jan