日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

EZH2 Inhibition Reshapes 3D Chromatin Architecture to Induce Immunogenic Phenotype in Small Cell Lung Cancer

EZH2抑制重塑3D染色质结构,诱导小细胞肺癌产生免疫原性表型

Parveen, Sana; Adhinaveni, Ramesh; Fang, Kun; Choppavarapu, Lavanya; Du, Meijun; Leone, Gustavo; de Sarkar, Navonil; Jin, Victor; Chen, Hui-Zi

DNA replication in primary hepatocytes without the six-subunit ORC.

原代肝细胞中缺乏六亚基ORC的DNA复制

Przanowska Róża K, Chen Yuechuan, Uchida Takayuki-Okano, Shibata Etsuko, Hao Xiaoxiao, Rueda Isaac Segura, Jensen Kate, Przanowski Piotr, Trimboli Anthony, Shibata Yoshiyuki, Leone Gustavo, Dutta Anindya

Disruption of the Placenta-Brain Axis in Transgenic Mice Lacking Serotonin Transporter (SERT) in Trophoblast Cells

缺乏滋养层细胞中血清素转运蛋白(SERT)的转基因小鼠胎盘-脑轴紊乱

Ellenberger, David T; Lyu, Zhen; Herrington, Rosalind T B; Kinkade, Jessica A; Leone, Gustavo W; Sze, Ji Ying; Bivens, Nathan J; Baker, R Frank; Roberts, R Michael; Joshi, Trupti; Rosenfeld, Cheryl S

Integrated single-cell analysis reveals distinct epigenetic-regulated cancer cell states and a heterogeneity-guided core signature in tamoxifen-resistant breast cancer.

整合的单细胞分析揭示了耐他莫昔芬乳腺癌中不同的表观遗传调控癌细胞状态和异质性引导的核心特征

Fang Kun, Ohihoin Aigbe G, Liu Tianxiang, Choppavarapu Lavanya, Nosirov Bakhtiyor, Wang Qianben, Yu Xue-Zhong, Kamaraju Sailaja, Leone Gustavo, Jin Victor X

RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

RNA结合蛋白FXR1通过将eIF4F复合物募集到翻译起始位点来驱动cMYC翻译。

George, Jasmine; Li, Yongsheng; Kadamberi, Ishaque P; Parashar, Deepak; Tsaih, Shirng-Wern; Gupta, Prachi; Geethadevi, Anjali; Chen, Changliang; Ghosh, Chandrima; Sun, Yunguang; Mittal, Sonam; Ramchandran, Ramani; Rui, Hallgeir; Lopez-Berestein, Gabriel; Rodriguez-Aguayo, Cristian; Leone, Gustavo; Rader, Janet S; Sood, Anil K; Dey, Madhusudan; Pradeep, Sunila; Chaluvally-Raghavan, Pradeep

Imaging Mass Spectrometry Reveals Alterations in N-Linked Glycosylation That Are Associated With Histopathological Changes in Nonalcoholic Steatohepatitis in Mouse and Human

成像质谱法揭示了小鼠和人类非酒精性脂肪性肝炎中与组织病理学变化相关的N-连接糖基化改变

Ochoa-Rios, Shaaron; O'Connor, Ian P; Kent, Lindsey N; Clouse, Julian M; Hadjiyannis, Yannis; Koivisto, Christopher; Pecot, Thierry; Angel, Peggi M; Drake, Richard R; Leone, Gustavo; Mehta, Anand S; Rockey, Don C

Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner

基质p53以癌基因特异性方式调控乳腺癌发展、免疫环境和存活

Wu, Jinghai; Liu, Xin; Reeser, Julie A Wallace; Trimboli, Anthony J; Pécot, Thierry; Sizemore, Gina M; Naidu, Shan K; Fernandez, Soledad A; Yu, Lianbo; Hallett, Michael; Park, Morag; Leone, Gustavo W; Hildreth, Blake E; Ostrowski, Michael C

Deep learning tools and modeling to estimate the temporal expression of cell cycle proteins from 2D still images

利用深度学习工具和建模方法,从二维静态图像中估计细胞周期蛋白的时间表达。

Pécot, Thierry; Cuitiño, Maria C; Johnson, Roger H; Timmers, Cynthia; Leone, Gustavo

Stromal Platelet-Derived Growth Factor Receptor-β Signaling Promotes Breast Cancer Metastasis in the Brain

基质血小板衍生生长因子受体β信号通路促进乳腺癌脑转移

Thies, Katie A; Hammer, Anisha M; Hildreth, Blake E 3rd; Steck, Sarah A; Spehar, Jonathan M; Kladney, Raleigh D; Geisler, Jennifer A; Das, Manjusri; Russell, Luke O; Bey, Jerome F 4th; Bolyard, Chelsea M; Pilarski, Robert; Trimboli, Anthony J; Cuitiño, Maria C; Koivisto, Christopher S; Stover, Daniel G; Schoenfield, Lynn; Otero, Jose; Godbout, Jonathan P; Chakravarti, Arnab; Ringel, Matthew D; Ramaswamy, Bhuvaneswari; Li, Zaibo; Kaur, Balveen; Leone, Gustavo; Ostrowski, Michael C; Sizemore, Steven T; Sizemore, Gina M

Protein Phosphatase 2A Activation Via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

在抗磷脂综合征小鼠模型中,滋养层细胞中ApoER2介导的蛋白磷酸酶2A激活可导致先兆子痫。

Chu, Haiyan; Sacharidou, Anastasia; Nguyen, An; Li, Chun; Chambliss, Ken L; Salmon, Jane E; Shen, Yu-Min; Lo, Julie; Leone, Gustavo W; Herz, Joachim; Hui, David Y; Marciano, Denise K; Abrahams, Vikki M; Natale, Bryony V; Montalbano, Alina P; Xiao, Xue; Xu, Lin; Natale, David R; Shaul, Philip W; Mineo, Chieko