Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death.
热量限制通过重塑碳水化合物和脂质代谢、改变过氧化物酶体和线粒体功能以及推迟凋亡和脂质坏死等受调控细胞死亡方式的发生,来延缓酵母的自然衰老
期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.24604
Arlia-Ciommo Anthony, Leonov Anna, Beach Adam, Richard Vincent R, Bourque Simon D, Burstein Michelle T, Kyryakov Pavlo, Gomez-Perez Alejandra, Koupaki Olivia, Feldman Rachel, Titorenko Vladimir I