文献库，生知库 | 链接生命科学的每一步

日期影响因子

Identification of molecularly targeted therapy-induced immunopeptidome in diffuse midline glioma (DMG)

弥漫性中线胶质瘤（DMG）中分子靶向治疗诱导的免疫肽组的鉴定

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2026.101278

Khairkhah, Niloofar; Owolabi, Habeebah; Namvar, Ali; Ibrahim, Mostafa M H; Nyayapathy, Seeta; Jones, Richard; Rumble, Julie M; Whitehead, Christopher E; Sebolt-Leopold, Judith S; Everest-Dass, Arun; Galban, Stefanie

免疫/内分泌

发表日期：2026

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Inhibition of DNA-PK may improve response to neoadjuvant chemoradiotherapy in rectal cancer.

抑制 DNA-PK 可改善直肠癌新辅助放化疗的疗效

期刊:Neoplasia

影响因子:7.7

doi:10.1016/j.neo.2022.01.004

Smithson Mary, Irwin Regina K, Williams Gregory, McLeod M Chandler, Choi E Karen, Ganguly Anutosh, Pepple Ashley, Cho Clifford S, Willey Christopher D, Leopold Judith, Hardiman Karin M

发表日期：2022

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Development of Preclinical Models to Understand and Treat Colorectal Cancer

开发用于了解和治疗结直肠癌的临床前模型

期刊:Clinics in Colon and Rectal Surgery

影响因子:1.1

doi:10.1055/s-0037-1602240

Sebolt-Leopold, Judith S

发表日期：2018

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Targeting ADAM17 inhibits human colorectal adenocarcinoma progression and tumor-initiating cell frequency

靶向ADAM17可抑制人类结直肠腺癌的进展和肿瘤起始细胞频率

期刊:Oncotarget

doi:10.18632/oncotarget.17780

Dosch, Joseph; Ziemke, Elizabeth; Wan, Shanshan; Luker, Kathryn; Welling, Theodore; Hardiman, Karin; Fearon, Eric; Thomas, Suneetha; Flynn, Matthew; Rios-Doria, Jonathan; Hollingsworth, Robert; Herbst, Ronald; Hurt, Elaine; Sebolt-Leopold, Judith

细胞生物学

发表日期：2017

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Tumor-selective proteotoxicity of verteporfin inhibits colon cancer progression independently of YAP1

维替泊芬的肿瘤选择性蛋白毒性抑制结肠癌进展，且该抑制作用独立于YAP1。

期刊:Science Signaling

影响因子:6.6

doi:10.1126/scisignal.aac5418

Zhang, Huabing; Ramakrishnan, Sadeesh K; Triner, Daniel; Centofanti, Brook; Maitra, Dhiman; Győrffy, Balázs; Sebolt-Leopold, Judith S; Dame, Michael K; Varani, James; Brenner, Dean E; Fearon, Eric R; Omary, M Bishr; Shah, Yatrik M

发表日期：2015

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Dual inhibition of allosteric mitogen-activated protein kinase (MEK) and phosphatidylinositol 3-kinase (PI3K) oncogenic targets with a bifunctional inhibitor

利用双功能抑制剂对变构丝裂原活化蛋白激酶 (MEK) 和磷脂酰肌醇 3-激酶 (PI3K) 致癌靶点进行双重抑制

期刊:Bioorganic & Medicinal Chemistry

doi:10.1016/j.bmc.2015.02.053

Van Dort, Marcian E; Galbán, Stefanie; Wang, Hanxiao; Sebolt-Leopold, Judith; Whitehead, Christopher; Hong, Hao; Rehemtulla, Alnawaz; Ross, Brian D

发表日期：2015

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MAPK signaling is required for dedifferentiation of acinar cells and development of pancreatic intraepithelial neoplasia in mice

MAPK信号通路是小鼠腺泡细胞去分化和胰腺上皮内瘤变发展所必需的。

期刊:Gastroenterology

影响因子:25.1

doi:10.1053/j.gastro.2013.11.052

Collins, Meredith A; Yan, Wei; Sebolt-Leopold, Judith S; Pasca di Magliano, Marina

细胞生物学

发表日期：2014

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ERK activation is required for CCK-mediated pancreatic adaptive growth in mice.

小鼠胰腺适应性生长需要 ERK 激活，而 CCK 是其生长的必要条件

期刊:American Journal of Physiology-Gastrointestinal and Liver Physiology

影响因子:3.3

doi:10.1152/ajpgi.00163.2014

Holtz Bryan J, Lodewyk Kevin B, Sebolt-Leopold Judith S, Ernst Stephen A, Williams John A

发表日期：2014

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Cotargeting MAPK and PI3K signaling with concurrent radiotherapy as a strategy for the treatment of pancreatic cancer

以MAPK和PI3K信号通路联合放疗作为胰腺癌治疗策略

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-12-0098

Williams, Terence M; Flecha, Athena R; Keller, Paul; Ram, Ashwin; Karnak, David; Galbán, Stefanie; Galbán, Craig J; Ross, Brian D; Lawrence, Theodore S; Rehemtulla, Alnawaz; Sebolt-Leopold, Judith

发表日期：2012

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Compensatory pathways induced by MEK inhibition are effective drug targets for combination therapy against castration-resistant prostate cancer

MEK抑制诱导的补偿通路是治疗去势抵抗性前列腺癌联合疗法的有效药物靶点。

期刊:Molecular Cancer Therapeutics

影响因子:5.5

doi:10.1158/1535-7163.MCT-10-1033

Gioeli, Daniel; Wunderlich, Winfried; Sebolt-Leopold, Judith; Bekiranov, Stefan; Wulfkuhle, Julia D; Petricoin, Emanuel F 3rd; Conaway, Mark; Weber, Michael J

发表日期：2011

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