日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Optimized ACE2-Fc fusion proteins with picomolar neutralization activity against highly evolved SARS-CoV-2 variants

针对高度进化的SARS-CoV-2变种具有皮摩尔级中和活性的优化ACE2-Fc融合蛋白

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.70489
Abancó, Ferran; Tarrés-Freixas, Ferran; Lepore, Rosalba; Molina-Molina, Elisa; Franco, Eloi; Boreika, Rytis; Pradenas, Edwards; Raïch-Regué, Dàlia; Erkizia, Itziar; Clotet, Bonaventura; Valencia, Alfonso; Vergara-Alert, Júlia; Segalés, Joaquim; Carrillo, Jorge; Izquierdo-Useros, Nuria; Blanco, Julià; Trinité, Benjamin
SARS-CoV-2
ACE2
发表日期：2026
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Patient stratification reveals the molecular basis of disease co-occurrences

患者分层揭示疾病共存的分子基础

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2421060122
Urda-García, Beatriz; Sánchez-Valle, Jon; Lepore, Rosalba; Valencia, Alfonso
发表日期：2025
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Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease

肺组织多层网络分析揭示慢性阻塞性肺疾病的分子异质性

期刊:American Journal of Respiratory and Critical Care Medicine
影响因子:19.4
doi:10.1164/rccm.202303-0500OC
Olvera, Nuria; Sánchez-Valle, Jon; Núñez-Carpintero, Iker; Rojas-Quintero, Joselyn; Noell, Guillaume; Casas-Recasens, Sandra; Faiz, Alen; Hansbro, Philip; Guirao, Angela; Lepore, Rosalba; Cirillo, Davide; Agustí, Alvar; Polverino, Francesca; Valencia, Alfonso; Faner, Rosa
慢性阻塞性肺疾病
发表日期：2024
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Prevalence and differences in the co-administration of drugs known to interact: an analysis of three distinct and large populations

已知存在相互作用的药物联合用药的普遍性和差异：对三个不同且规模较大的人群的分析

期刊:BMC Medicine
影响因子:8.3
doi:10.1186/s12916-024-03384-1
Sánchez-Valle, Jon; Correia, Rion Brattig; Camacho-Artacho, Marta; Lepore, Rosalba; Mattos, Mauro M; Rocha, Luis M; Valencia, Alfonso
发表日期：2024
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Novel Spike-stabilized trimers with improved production protect K18-hACE2 mice and golden Syrian hamsters from the highly pathogenic SARS-CoV-2 Beta variant.

新型刺突蛋白稳定三聚体通过改进生产工艺保护 K18-hACE2 小鼠和金叙利亚仓鼠免受高致病性 SARS-CoV-2 Beta 变体的感染

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2023.1291972
Ávila-Nieto Carlos, Vergara-Alert Júlia, Amengual-Rigo Pep, Ainsua-Enrich Erola, Brustolin Marco, Rodríguez de la Concepción María Luisa, Pedreño-Lopez Núria, Rodon Jordi, Urrea Victor, Pradenas Edwards, Marfil Silvia, Ballana Ester, Riveira-Muñoz Eva, Pérez Mònica, Roca Núria, Tarrés-Freixas Ferran, Carabelli Julieta, Cantero Guillermo, Pons-Grífols Anna, Rovirosa Carla, Aguilar-Gurrieri Carmen, Ortiz Raquel, Barajas Ana, Trinité Benjamin, Lepore Rosalba, Muñoz-Basagoiti Jordana, Perez-Zsolt Daniel, Izquierdo-Useros Nuria, Valencia Alfonso, Blanco JuliÃ, Clotet Bonaventura, Guallar Victor, Segalés Joaquim, Carrillo Jorge
炎症/感染
新冠
ACE2
发表日期：2023
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Analysis of electronic health records from three distinct and large populations reveals high prevalence and biases in the co-administration of drugs known to interact

对来自三个不同且规模庞大的人群的电子健康记录进行分析发现，已知存在相互作用的药物联合用药的普遍性较高，且存在偏倚。

期刊:
影响因子:
doi:10.1101/2023.02.06.23285566
Sánchez-Valle, Jon; Correia, Rion Brattig; Camacho-Artacho, Marta; Lepore, Rosalba; Mattos, Mauro M; Rocha, Luis M; Valencia, Alfonso
发表日期：2023
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Heterogeneous Infectivity and Pathogenesis of SARS-CoV-2 Variants Beta, Delta and Omicron in Transgenic K18-hACE2 and Wildtype Mice.

SARS-CoV-2 变种 β、δ 和 δν 在转基因 K18-hACE2 小鼠和野生型小鼠中的异质性感染性和致病性

期刊:Frontiers in Microbiology
影响因子:4.5
doi:10.3389/fmicb.2022.840757
Tarrés-Freixas Ferran, Trinité Benjamin, Pons-Grífols Anna, Romero-Durana Miguel, Riveira-Muñoz Eva, Ávila-Nieto Carlos, Pérez Mónica, Garcia-Vidal Edurne, Perez-Zsolt Daniel, Muñoz-Basagoiti Jordana, Raïch-Regué Dàlia, Izquierdo-Useros Nuria, Andrés Cristina, Antón Andrés, Pumarola Tomàs, Blanco Ignacio, Noguera-Julián Marc, Guallar Victor, Lepore Rosalba, Valencia Alfonso, Urrea Victor, Vergara-Alert Júlia, Clotet Bonaventura, Ballana Ester, Carrillo Jorge, Segalés Joaquim, Blanco JuliÃ
炎症/感染
新冠
ACE2
发表日期：2022
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DGLinker: flexible knowledge-graph prediction of disease-gene associations

DGLinker：基于灵活知识图谱的疾病基因关联预测

期刊:Nucleic Acids Research
影响因子:13.1
doi:10.1093/nar/gkab449
Hu, Jiajing; Lepore, Rosalba; Dobson, Richard J B; Al-Chalabi, Ammar; M Bean, Daniel; Iacoangeli, Alfredo
发表日期：2021
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Quantitative Description of Surface Complementarity of Antibody-Antigen Interfaces

抗体-抗原界面表面互补性的定量描述

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2021.749784
Di Rienzo, Lorenzo; Milanetti, Edoardo; Ruocco, Giancarlo; Lepore, Rosalba
发表日期：2021
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Assessing the accuracy of contact and distance predictions in CASP14

评估 CASP14 中接触和距离预测的准确性

期刊:Proteins-Structure Function and Bioinformatics
影响因子:2.8
doi:10.1002/prot.26248
Ruiz-Serra, Victoria; Pontes, Camila; Milanetti, Edoardo; Kryshtafovych, Andriy; Lepore, Rosalba; Valencia, Alfonso
SP1
CASP1
发表日期：2021
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