Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Study of the Penetration of a Monoclonal Antibody Combination (ASN100) Targeting Staphylococcus aureus Cytotoxins in the Lung Epithelial Lining Fluid of Healthy Volunteers
一项随机、双盲、安慰剂对照、单次递增剂量研究,旨在评估靶向金黄色葡萄球菌细胞毒素的单克隆抗体组合(ASN100)在健康志愿者肺上皮衬液中的渗透性。
期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00350-19
Magyarics, Zoltan; Leslie, Fraser; Bartko, Johann; Rouha, Harald; Luperchio, Steven; Schörgenhofer, Christian; Schwameis, Michael; Derhaschnig, Ulla; Lagler, Heimo; Stiebellehner, Leopold; Firbas, Christa; Weber, Susanne; Campanaro, Ed; Jilma, Bernd; Nagy, Eszter; Stevens, Chris