日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Emerging liquid biopsy tools to analyse cancer biomarkers: electrochemical sensors and extracellular vesicle analysis

用于分析癌症生物标志物的新兴液体活检工具:电化学传感器和细胞外囊泡分析

Devadoss, Anitha; Furness, Michael R; Wu, Nathan J W; Oikonomidou, Olga; Kersaudy-Kerhoas, Maïwenn; Leslie, Nick R

Identification of a PTEN mutation with reduced protein stability, phosphatase activity, and nuclear localization in Hong Kong patients with autistic features, neurodevelopmental delays, and macrocephaly

在香港患有自闭症特征、神经发育迟缓和巨头畸形的患者中,鉴定出一种 PTEN 突变,该突变导致蛋白质稳定性、磷酸酶活性和核定位降低。

Wong, Chi Wai; Or, Penelope Mei Yu; Wang, Yubing; Li, Lisha; Li, Jing; Yan, Mingfei; Cao, Ye; Luk, Ho Ming; Tong, Tony Ming For; Leslie, Nick R; Lo, Ivan Fai-Man; Choy, Kwong Wai; Chan, Andrew Man Lok

Cross talk between the Akt and p38α pathways in macrophages downstream of Toll-like receptor signaling

Toll样受体信号传导下游巨噬细胞中Akt和p38α通路之间的相互作用

McGuire, Victoria A; Gray, Alexander; Monk, Claire E; Santos, Susana G; Lee, Keunwook; Aubareda, Anna; Crowe, Jonathan; Ronkina, Natalia; Schwermann, Jessica; Batty, Ian H; Leslie, Nick R; Dean, Jonathan L E; O'Keefe, Stephen J; Boothby, Mark; Gaestel, Matthias; Arthur, J Simon C

Mechanism of activation of PKB/Akt by the protein phosphatase inhibitor Calyculin A

蛋白磷酸酶抑制剂钙调蛋白A激活PKB/Akt的机制

Pozuelo-Rubio, Mercedes; Leslie, Nick R; Murphy, Jane; Mackintosh, Carol

PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration

PTEN在细胞迁移调控中发挥PtdIns(3,4,5)P(3)依赖性和非依赖性作用

Leslie, Nick R; Yang, Xuesong; Downes, C Peter; Weijer, Cornelis J

PTEN is destabilized by phosphorylation on Thr366.

PTEN 在 Thr366 位点磷酸化后不稳定

Maccario Helene, Perera Nevin M, Davidson Lindsay, Downes C Peter, Leslie Nick R

A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells

下丘脑细胞系和胰岛β细胞中通过PTEN抑制介导的新型瘦素信号通路

Ning, Ke; Miller, Lisa C; Laidlaw, Hilary A; Burgess, Laura A; Perera, Nevin M; Downes, C Peter; Leslie, Nick R; Ashford, Michael L J

PTEN function: how normal cells control it and tumour cells lose it

PTEN功能:正常细胞如何控制它,以及肿瘤细胞如何失去它

Leslie, Nick R; Downes, C Peter

Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases

人二腺苷多磷酸代谢Nudix水解酶hAps1和hAps2的克隆和鉴定

Leslie, Nick R; McLennan, Alexander G; Safrany, Stephen T