日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CNS-derived extracellular vesicles from superoxide dismutase 1 (SOD1)G93A ALS mice originate from astrocytes and neurons and carry misfolded SOD1

超氧化物歧化酶 1 (SOD1)G93A ALS 小鼠的 CNS 衍生细胞外囊泡源自星形胶质细胞和神经元,并携带错误折叠的 SOD1

Judith M Silverman, Darren Christy, Chih Cheih Shyu, Kyung-Mee Moon, Sarah Fernando, Zoe Gidden, Catherine M Cowan, Yuxin Ban, R Greg Stacey, Leslie I Grad, Luke McAlary, Ian R Mackenzie, Leonard J Foster, Neil R Cashman

Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites

竞争性细胞器特异性适配器将 Vps13 募集到膜接触位点

Björn D M Bean, Samantha K Dziurdzik, Kathleen L Kolehmainen, Claire M S Fowler, Waldan K Kwong, Leslie I Grad, Michael Davey, Cayetana Schluter, Elizabeth Conibear

TDP-43 or FUS-induced misfolded human wild-type SOD1 can propagate intercellularly in a prion-like fashion

TDP-43 或 FUS 诱导的错误折叠的人类野生型 SOD1 可以以类似朊病毒的方式在细胞间传播

Edward Pokrishevsky, Leslie I Grad, Neil R Cashman

Intercellular propagated misfolding of wild-type Cu/Zn superoxide dismutase occurs via exosome-dependent and -independent mechanisms

野生型 Cu/Zn 超氧化物歧化酶的细胞间传播错误折叠是通过外泌体依赖性和非依赖性机制发生的

Leslie I Grad, Justin J Yerbury, Bradley J Turner, William C Guest, Edward Pokrishevsky, Megan A O'Neill, Anat Yanai, Judith M Silverman, Rafaa Zeineddine, Lisa Corcoran, Janet R Kumita, Leila M Luheshi, Masoud Yousefi, Bradley M Coleman, Andrew F Hill, Steven S Plotkin, Ian R Mackenzie, Neil R Cash

Aberrant localization of FUS and TDP43 is associated with misfolding of SOD1 in amyotrophic lateral sclerosis

FUS 和 TDP43 的异常定位与肌萎缩侧索硬化症中 SOD1 的错误折叠有关

Edward Pokrishevsky, Leslie I Grad, Masoud Yousefi, Jing Wang, Ian R Mackenzie, Neil R Cashman

Intermolecular transmission of superoxide dismutase 1 misfolding in living cells

超氧化物歧化酶1错误折叠在活细胞内的分子间传递

Leslie I Grad, Will C Guest, Anat Yanai, Edward Pokrishevsky, Megan A O'Neill, Ebrima Gibbs, Valentyna Semenchenko, Masoud Yousefi, David S Wishart, Steven S Plotkin, Neil R Cashman