日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MitoQ reduces senescence burden in doxorubicin-treated endothelial cells by reducing mitochondrial ROS and DNA damage.

MitoQ 通过减少线粒体 ROS 和 DNA 损伤来减轻阿霉素处理的内皮细胞的衰老负担。

Abdeahad Hossein, Moreno Denisse G, Bloom Samuel I, Norman Lucas, Lesniewski Lisa A, Donato Anthony J

Late-Life Aerobic Exercise Attenuates DNA Damage and Telomere Dysfunction in Non-Atheroprone but Not in Atheroprone Aortic Regions

老年时期进行有氧运动可减轻非动脉粥样硬化易感区域主动脉的DNA损伤和端粒功能障碍,但对动脉粥样硬化易感区域的主动脉则无此作用。

Lim, Jisok; Kim, John; Abdeahad, Hossein; Hall, Shelby A; Lesniewski, Lisa A; Donato, Anthony J

Glycocalyx-targeted therapy prevents age-related muscle loss and declines in maximal exercise capacity

糖萼靶向疗法可预防与年龄相关的肌肉流失和最大运动能力下降

Machin, Daniel R; Islam, Md Torikul; Malouf, Alec; Nguyen, Daniel; Sabouri, Mostafa; Boulos, Maryana; Horn, Andrew G; Schulze, Kiana M; Layec, Gwenael; Lesniewski, Lisa A; Donato, Anthony J

Endothelial-Specific Reduction in Arf6 Impairs Insulin-Stimulated Vasodilation and Skeletal Muscle Blood Flow Resulting in Systemic Insulin Resistance in Mice

内皮细胞特异性降低Arf6会损害胰岛素刺激的血管舒张和骨骼肌血流,导致小鼠出现全身性胰岛素抵抗

Islam, Md Torikul; Cai, Jinjin; Allen, Shanena; Moreno, Denisse G; Bloom, Samuel I; Bramwell, R Colton; Mitton, Jonathan; Horn, Andrew G; Zhu, Weiquan; Donato, Anthony J; Holland, William L; Lesniewski, Lisa A

Targeting vascular senescence in cardiovascular disease with aging

针对心血管疾病中的血管衰老进行治疗

Hall, Shelby A; Lesniewski, Lisa A

Mechanisms and consequences of endothelial cell senescence

内皮细胞衰老的机制和后果

Bloom, Samuel I; Islam, Md Torikul; Lesniewski, Lisa A; Donato, Anthony J

Advancing age increases the size and severity of spontaneous atheromas in mouse models of atherosclerosis

在动脉粥样硬化小鼠模型中,年龄增长会增加自发性动脉粥样硬化斑块的大小和严重程度。

Gogulamudi, Venkateswara R; Durrant, Jessica R; Adeyemo, Adelola O; Ho, Huynh Mi; Walker, Ashley E; Lesniewski, Lisa A

Glycocalyx-targeted therapy ameliorates age-related arterial dysfunction

糖萼靶向治疗可改善与年龄相关的动脉功能障碍

Machin, Daniel R; Trott, Daniel W; Gogulamudi, Venkateswara R; Islam, Md Torikul; Bloom, Samuel I; Vink, Hans; Lesniewski, Lisa A; Donato, Anthony J

Endothelial specific reduction in Arf6 impairs insulin-stimulated vasodilation and skeletal muscle blood flow resulting in systemic insulin resistance

内皮细胞特异性Arf6减少会损害胰岛素刺激的血管舒张和骨骼肌血流,从而导致全身性胰岛素抵抗。

Islam, Md Torikul; Cai, Jinjin; Allen, Shanena; Moreno, Denisse G; Bloom, Samuel I; Bramwell, R Colton; Mitton, Jonathan; Horn, Andrew G; Zhu, Weiquan; Donato, Anthony J; Holland, William L; Lesniewski, Lisa A

Senolytics Reduce Endothelial Cell DNA Damage and Telomere Dysfunction Despite Reductions in Telomere Length.

尽管端粒长度缩短,但衰老细胞清除剂可减少内皮细胞 DNA 损伤和端粒功能障碍

Bloom Samuel I, Tuday Eric, Islam Torikul, Gogulamudi Venkateswara R, Lesniewski Lisa A, Donato Anthony J