PET clinical study of novel antipsychotic LB-102 demonstrates unexpectedly prolonged dopamine receptor target engagement
一项针对新型抗精神病药物LB-102的PET临床研究显示,其与多巴胺受体靶点的结合时间出乎意料地延长。
期刊:Neuropsychopharmacology
影响因子:7.1
doi:10.1038/s41386-024-01951-x
Wong, Dean F; Chand, Ganesh B; Caito, Nicole; Eramo, Anna; Grattan, Vincent T; Hixon, Mark S; Nicol, Ginger; Lessie, Erin; Prensky, Zachary; Kuwabara, Hiroto; Tian, Lucy; Valenta, Ines; Schindler, Thomas H; Gründer, Gerhard; Vaino, Andrew R