日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mesothelioma location influences the tumour microenvironment and immune checkpoint therapy response in preclinical models

间皮瘤的位置会影响临床前模型中的肿瘤微环境和免疫检查点疗法反应。

Orozco Morales, M Lizeth; Lansley, Sally M; Chin, Wee Loong; Tilsed, Caitlin M; Principe, Nicola; Leslie, Connull; Vitali, Breana J; Rwandamuriye, Francois X; de Jong, Emma; Kidman, Joel; Zemek, Rachael M; Rinaldi, Catherine A; Lassmann, Timo; Bosco, Anthony; Lee, Y C Gary; Lake, Richard A; Chee, Jonathan; Lesterhuis, W Joost

Comparative analysis of malignant pleural effusion and peripheral blood reveals unique T cell signatures associated with survival in mesothelioma patients

恶性胸腔积液和外周血的比较分析揭示了与间皮瘤患者生存相关的独特T细胞特征

Principe, Nicola; Stevens, Kofi L P; Phung, Amber-Lee; McCoy, Melanie; Kidman, Joel; Ismail, Ali; Cook, Alistair M; Chopra, Abha; Watson, Mark; Robinson, Bruce W; Creaney, Jenette; Lee, Y C Gary; Waithman, Jason; Lesterhuis, W Joost; Lake, Richard A; Nowak, Anna K; Chee, Jonathan; McDonnell, Alison M

Coupling of response biomarkers between tumor and peripheral blood in patients undergoing chemoimmunotherapy.

接受化疗免疫治疗的患者肿瘤和外周血中反应生物标志物的耦合

Chin Wee Loong, Cook Alistair M, Chee Jonathan, Principe Nicola, Hoang Tracy S, Kidman Joel, Hmon Khaing P W, Yeow Yen, Jones Matthew E, Hou Rui, Denisenko Elena, McDonnell Alison M, Hon Chung-Chau, Moody Jonathan, Anderson Denise, Yip Sonia, Cummins Michelle M, Stockler Martin R, Kok Peey-Sei, Brown Chris, John Thomas, Kao Steven C-H, Karikios Deme J, O'Byrne Kenneth J, Hughes Brett G M, Lake Richard A, Forrest Alistair R R, Nowak Anna K, Lassmann Timo, Lesterhuis W Joost

Anti-metabolite chemotherapy increases LAG-3 expressing tumor-infiltrating lymphocytes which can be targeted by combination immune checkpoint blockade

抗代谢化疗会增加表达LAG-3的肿瘤浸润淋巴细胞,这些细胞可作为联合免疫检查点阻断疗法的靶点。

Principe, Nicola; Phung, Amber-Lee; Stevens, Kofi L P; Elaskalani, Omar; Wylie, Ben; Tilsed, Caitlin M; Sheikh, Fezaan; Orozco Morales, M Lizeth; Kidman, Joel; Marcq, Elly; Fisher, Scott A; Nowak, Anna K; McDonnell, Alison M; Lesterhuis, W Joost; Chee, Jonathan

Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy

免疫检查点治疗后小鼠 AB1 间皮瘤和 Renca 肾癌的时程 RNAseq 数据

Wee Loong Chin #, Rachael M Zemek #, Caitlin M Tilsed, Alistair R R Forrest, Vanessa S Fear, Catherine Forbes, Louis Boon, Anthony Bosco, Belinda B Guo, Michael J Millward, Anna K Nowak, Richard A Lake, W Joost Lesterhuis, Timo Lassmann5

The MexTAg collaborative cross: host genetics affects asbestos related disease latency, but has little influence once tumours develop

MexTAg合作研究发现:宿主遗传因素会影响石棉相关疾病的潜伏期,但对肿瘤发展后的影响甚微。

Fisher, Scott A; Patrick, Kimberley; Hoang, Tracy; Marcq, Elly; Behrouzfar, Kiarash; Young, Sylvia; Miller, Timothy J; Robinson, Bruce W S; Bueno, Raphael; Nowak, Anna K; Lesterhuis, W Joost; Morahan, Grant; Lake, Richard A

An Interprofessional Faculty Development Program for Workplace-Based Learning

面向工作场所学习的跨专业教师发展计划

Booij, Eveline; van Dam, Marjel; Jonker, Gersten; van Bruggen, Lisette; Lesterhuis, Marije; van der Schaaf, Marieke F; Hoff, Reinier G; Hennus, Marije P

Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner

维甲酸以模型选择性方式增强环磷酰胺的抗癌反应。

Tilsed, Caitlin M; Morales, M Lizeth Orozco; Zemek, Rachael M; Gordon, Brianna A; Piggott, Matthew J; Nowak, Anna K; Fisher, Scott A; Lake, Richard A; Lesterhuis, W Joost

Protocol for delivery of intraoperative immunotherapy to mice by surgical debulking of subcutaneous tumors

通过手术减瘤为小鼠提供术中免疫治疗的方案

Francois Xavier Rwandamuriye, Breana Vitali, Juliët Schreurs, Tao Wang, Emily Barrick, Killugudi Swaminathan Iyer, Willem Joost Lesterhuis, Rachael M Zemek, Ben Wylie

A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence

手术优化后的术中聚肌苷酸-聚胞苷酸(poly(I:C))释放水凝胶可预防癌症复发

Francois Xavier Rwandamuriye ,Cameron W Evans ,Ben Wylie ,Marck Norret ,Breana Vitali ,Diwei Ho ,Dat Nguyen ,Ellise A Roper ,Tao Wang ,Matt S Hepburn ,Rowan W Sanderson ,Maren Pfirrmann ,Vanessa S Fear ,Catherine A Forbes ,Ken Wyatt ,Anne L Ryan ,Terrance G Johns ,Marianne B Phillips ,Rupert Hodder ,Connull Leslie ,Brendan F Kennedy ,Rachael M Zemek ,Killugudi Swaminathan Iyer ,Willem Joost Lesterhuis