日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Support academic access to automated cloud labs to improve reproducibility

支持学术界使用自动化云实验室以提高可重复性

Armer, Chase; Letronne, Florent; DeBenedictis, Erika

APOE2 orchestrated differences in transcriptomic and lipidomic profiles of postmortem AD brain

APOE2 调控阿尔茨海默症死后脑组织转录组和脂质组学特征的差异

Iliya Lefterov, Cody M Wolfe, Nicholas F Fitz, Kyong Nyon Nam, Florent Letronne, Richard J Biedrzycki, Julia Kofler, Xianlin Han, Jianing Wang, Jonathan Schug, Radosveta Koldamova

ABCA1 haplodeficiency affects the brain transcriptome following traumatic brain injury in mice expressing human APOE isoforms

ABCA1单倍体缺乏症会影响表达人类APOE同种型的小鼠在创伤性脑损伤后的脑转录组。

Castranio, Emilie L; Wolfe, Cody M; Nam, Kyong Nyon; Letronne, Florent; Fitz, Nicholas F; Lefterov, Iliya; Koldamova, Radosveta

Integrated approach reveals diet, APOE genotype and sex affect immune response in APP mice

综合研究揭示饮食、APOE基因型和性别影响APP小鼠的免疫反应

Nam, Kyong Nyon; Wolfe, Cody M; Fitz, Nicholas F; Letronne, Florent; Castranio, Emilie L; Mounier, Anais; Schug, Jonathan; Lefterov, Iliya; Koldamova, Radosveta

Voxel-Based Statistical Analysis of 3D Immunostained Tissue Imaging

基于体素的三维免疫染色组织成像统计分析

Vandenberghe, Michel E; Souedet, Nicolas; Hérard, Anne-Sophie; Ayral, Anne-Marie; Letronne, Florent; Balbastre, Yaël; Sadouni, Elmahdi; Hantraye, Philippe; Dhenain, Marc; Frouin, Frédérique; Lambert, Jean-Charles; Delzescaux, Thierry

Gene co-expression networks identify Trem2 and Tyrobp as major hubs in human APOE expressing mice following traumatic brain injury

基因共表达网络确定 Trem2 和 Tyrobp 是创伤性脑损伤后人类 APOE 表达小鼠的主要枢纽

Emilie L Castranio, Anais Mounier, Cody M Wolfe, Kyong Nyon Nam, Nicholas F Fitz, Florent Letronne, Jonathan Schug, Radosveta Koldamova, Iliya Lefterov

Liver X receptor agonist treatment significantly affects phenotype and transcriptome of APOE3 and APOE4 Abca1 haplo-deficient mice

肝脏 X 受体激动剂治疗显著影响 APOE3 和 APOE4 Abca1 单倍体缺陷小鼠的表型和转录组

Alexis Y Carter, Florent Letronne, Nicholas F Fitz, Anais Mounier, Cody M Wolfe, Kyong Nyon Nam, Valerie L Reeves, Hafsa Kamboh, Iliya Lefterov, Radosveta Koldamova

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

ADAM30 通过激活组织蛋白酶 D 来下调阿尔茨海默病中的 APP 相关缺陷

Florent Letronne, Geoffroy Laumet, Anne-Marie Ayral, Julien Chapuis, Florie Demiautte, Mathias Laga, Michel E Vandenberghe, Nicolas Malmanche, Florence Leroux, Fanny Eysert, Yoann Sottejeau, Linda Chami, Amandine Flaig, Charlotte Bauer, Pierre Dourlen, Marie Lesaffre, Charlotte Delay, Ludovic Huot, 

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

BIN1 表达增加通过调节 tau 病理来介导阿尔茨海默病遗传风险

J Chapuis, F Hansmannel, M Gistelinck, A Mounier, C Van Cauwenberghe, K V Kolen, F Geller, Y Sottejeau, D Harold, P Dourlen, B Grenier-Boley, Y Kamatani, B Delepine, F Demiautte, D Zelenika, N Zommer, M Hamdane, C Bellenguez, J-F Dartigues, J-J Hauw, F Letronne, A-M Ayral, K Sleegers, A Schellens, L