日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination

转录因子CREB1是ALVAC疫苗免疫原性和降低HIV-1感染的机制驱动因素。

Jeffrey Alan Tomalka ,Adam Nicolas Pelletier ,Slim Fourati ,Muhammad Bilal Latif ,Ashish Sharma ,Kathryn Furr ,Kevin Carlson ,Michelle Lifton ,Ana Gonzalez ,Peter Wilkinson ,Genoveffa Franchini ,Robert Parks ,Norman Letvin ,Nicole Yates ,Kelly Seaton ,Georgia Tomaras ,Jim Tartaglia ,Merlin L Robb ,Nelson L Michael ,Richard Koup ,Barton Haynes ,Sampa Santra ,Rafick Pierre Sekaly

Recombinant MVA-prime elicits neutralizing antibody responses by inducing antigen-specific B cells in the germinal center

重组MVA-prime通过在生发中心诱导抗原特异性B细胞,从而引发中和抗体反应。

Leila Eslamizar # ,Constantinos Petrovas # ,David J Leggat ,Kathryn Furr ,Michelle L Lifton ,Gail Levine ,Steven Ma ,Christopher Fletez-Brant ,Wesley Hoyland ,Madhu Prabhakaran ,Sandeep Narpala ,Kristin Boswell ,Takuya Yamamoto ,Hua-Xin Liao ,David Pickup ,Elizabeth Ramsburg ,Laura Sutherland ,Adrian McDermott ,Mario Roederer ,David Montefiori ,Richard A Koup ,Barton F Haynes ,Norman L Letvin ,Sampa Santra

Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes

三部分基序 22 (TRIM22) 蛋白通过表观遗传沉默病毒早期基因来限制单纯疱疹病毒 1

Tejaswini S Reddi, Philipp E Merkl, So-Yon Lim, Norman L Letvin, David M Knipe

Influenza A Virus Infection Causes Chronic Lung Disease Linked to Sites of Active Viral RNA Remnants

甲型流感病毒感染导致慢性肺病与活性病毒 RNA 残留位点有关

Shamus P Keeler, Eugene V Agapov, Michael E Hinojosa, Adam N Letvin, Kangyun Wu, Michael J Holtzman

Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman Primates

疫苗诱导非人灵长类动物产生针对V3-糖链广谱中和表位的高甘露糖依赖性中和抗体

Saunders, Kevin O; Nicely, Nathan I; Wiehe, Kevin; Bonsignori, Mattia; Meyerhoff, R Ryan; Parks, Robert; Walkowicz, William E; Aussedat, Baptiste; Wu, Nelson R; Cai, Fangping; Vohra, Yusuf; Park, Peter K; Eaton, Amanda; Go, Eden P; Sutherland, Laura L; Scearce, Richard M; Barouch, Dan H; Zhang, Ruijun; Von Holle, Tarra; Overman, R Glenn; Anasti, Kara; Sanders, Rogier W; Moody, M Anthony; Kepler, Thomas B; Korber, Bette; Desaire, Heather; Santra, Sampa; Letvin, Norman L; Nabel, Gary J; Montefiori, David C; Tomaras, Georgia D; Liao, Hua-Xin; Alam, S Munir; Danishefsky, Samuel J; Haynes, Barton F

Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques

恒河猴接种ALVAC/AIDSVAX B/E gp120疫苗后组织记忆B细胞库分析

Kan Luo ,Hua-Xin Liao ,Ruijun Zhang ,David Easterhoff ,Kevin Wiehe ,Thaddeus C Gurley ,Lawrence C Armand ,Ashley A Allen ,Tarra A Von Holle ,Dawn J Marshall ,John F Whitesides ,Jamie Pritchett ,Andrew Foulger ,Giovanna Hernandez ,Robert Parks ,Krissey E Lloyd ,Christina Stolarchuk ,Sheetal Sawant ,Jessica Peel ,Nicole L Yates ,Erika Dunford ,Sabrina Arora ,Amy Wang ,Cindy M Bowman ,Laura L Sutherland ,Richard M Scearce ,Shi-Mao Xia ,Mattia Bonsignori ,Justin Pollara ,R Whitney Edwards ,Sampa Santra ,Norman L Letvin ,James Tartaglia ,Donald Francis ,Faruk Sinangil ,Carter Lee ,Jaranit Kaewkungwal ,Sorachai Nitayaphan ,Punnee Pitisuttithum ,Supachai Rerks-Ngarm ,Nelson L Michael ,Jerome H Kim ,S Munir Alam ,Nathan A Vandergrift ,Guido Ferrari ,David C Montefiori ,Georgia D Tomaras ,Barton F Haynes ,M Anthony Moody

Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates

急性感染期间细胞因子和趋化因子风暴的强度和性质可区分非人灵长类动物的非进展性和进展性猴免疫缺陷病毒感染

Keating, Sheila M; Heitman, John W; Wu, Shiquan; Deng, Xutao; Stacey, Andrea R; Zahn, Roland C; de la Rosa, Maurus; Finstad, Samantha L; Lifson, Jeffrey D; Piatak, Michael Jr; Gauduin, Marie-Claire; Kessler, Benedikt M; Ternette, Nicola; Carville, Angela; Johnson, R Paul; Desrosiers, Ronald C; Letvin, Norman L; Borrow, Persephone; Norris, Philip J; Schmitz, Joern E

Infection of rhesus macaques with a pool of simian immunodeficiency virus with the envelope genes from acute HIV-1 infections

用含有急性 HIV-1 感染包膜基因的猴免疫缺陷病毒混合物感染恒河猴

Krebs, Kendall C; Tian, Meijuan; Asmal, Mohammed; Ling, Binhua; Nelson, Kenneth; Henry, Kenneth; Gibson, Richard; Li, Yuejin; Han, Weining; Shattock, Robin J; Veazey, Ronald S; Letvin, Norman; Arts, Eric J; Gao, Yong

Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections

由急性 HIV-1 感染的 CCR5 包膜基因衍生而来的不断进化的 SIV-HIV 对恒河猴的致病性感染

Asmal, Mohammed; Lane, Sophie; Tian, Meijuan; Nickel, Gabrielle; Venner, Colin; Dirk, Brennan; Dikeakos, Jimmy; Luedemann, Corinne; Mach, Linh; Balachandran, Harikrishnan; Buzby, Adam; Rao, Srinivas; Letvin, Norman; Gao, Yong; Arts, Eric J

Regulatory T Cells Modulate DNA Vaccine Immunogenicity at Early Time via Functional CD4(+) T Cells and Antigen Duration

调节性T细胞通过功能性CD4(+) T细胞和抗原持续时间在早期调节DNA疫苗的免疫原性

Qin, Lizeng; Jiang, Guosheng; Han, Jinxiang; Letvin, Norman L