日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stage-dependent dual mechanisms of MORC2 in retrotransposon silencing and sex chromosome inactivation in germ cells

MORC2在逆转录转座子沉默和生殖细胞性染色体失活中的阶段依赖性双重机制

Kang, Zhenlong; Guo, Rui; Han, Shenglin; Yang, Fang; Zhang, Jinwen; Wang, Yuanyuan; Nelson, Kara A; Nallamala, Vamshidhar C; Leu, N Adrian; Li, Zhengyi; Liu, Jialong; Liang, Hongqing; Lan, Yemin; Faustino, Anneliese; Tang, Hsin-Yao; Modzelewski, Andrew J; Ye, Lan; Wang, P Jeremy

Iterative oxidation by TET1 is required for reprogramming of imprinting control regions and patterning of mouse sperm hypomethylated regions.

TET1 的迭代氧化作用是重编程印记控制区和小鼠精子低甲基化区模式所必需的

Prasasya Rexxi D, Caldwell Blake A, Liu Zhengfeng, Wu Songze, Leu N Adrian, Fowler Johanna M, Cincotta Steven A, Laird Diana J, Kohli Rahul M, Bartolomei Marisa S

TRIP13 localizes to synapsed chromosomes and functions as a dosage-sensitive regulator of meiosis

TRIP13定位于联会染色体,并作为减数分裂的剂量敏感性调节因子发挥作用。

Chotiner, Jessica Y; Leu, N Adrian; Yang, Fang; Cossu, Isabella G; Guan, Yongjuan; Lin, Huijuan; Wang, P Jeremy

The N-terminal modification of HORMAD2 causes its ectopic persistence on synapsed chromosomes without meiotic blockade.

HORMAD2 的 N 端修饰导致其在联会染色体上异位持续存在,而不会阻滞减数分裂

Cossu Isabella G, Leu N Adrian, Guan Yongjuan, Wang P Jeremy

Endothelial SARS-CoV-2 infection is not the underlying cause of COVID19-associated vascular pathology in mice

小鼠内皮细胞SARS-CoV-2感染并非COVID-19相关血管病变的根本原因。

Gao, Siqi; Tang, Alan T; Wang, Min; Buchholz, David W; Imbiakha, Brian; Yang, Jisheng; Chen, Xiaowen; Hewins, Peter; Mericko-Ishizuka, Patricia; Leu, N Adrian; Sterling, Stephanie; August, Avery; Jurado, Kellie A; Morrisey, Edward E; Aguilar-Carreno, Hector; Kahn, Mark L

MYC Hyperactivates Wnt Signaling in APC/CTNNB1-Mutated Colorectal Cancer Cells through miR-92a-Dependent Repression of DKK3

MYC通过miR-92a依赖性抑制DKK3,在APC/CTNNB1突变的结直肠癌细胞中过度激活Wnt信号通路。

Sehgal, Priyanka; Lanauze, Claudia; Wang, Xin; Hayer, Katharina E; Torres-Diz, Manuel; Leu, N Adrian; Sela, Yogev; Stanger, Ben Z; Lengner, Christopher J; Thomas-Tikhonenko, Andrei

FLACC1 is testis-specific but dispensable for fertility in mice

FLACC1是睾丸特异性的,但对小鼠的生育能力并非必需。

Chotiner, Jessica Y; Leu, N Adrian; Wang, P Jeremy

Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis

多梳蛋白SCML2与USP7结合,并在雄性减数分裂过程中拮抗XY染色质中的组蛋白H2A泛素化。

Luo, Mengcheng; Zhou, Jian; Leu, N Adrian; Abreu, Carla M; Wang, Jianle; Anguera, Montserrat C; de Rooij, Dirk G; Jasin, Maria; Wang, P Jeremy

The carboxy-terminus of p63 links cell cycle control and the proliferative potential of epidermal progenitor cells.

p63 的羧基末端与细胞周期控制和表皮祖细胞的增殖潜能有关

Suzuki Daisuke, Sahu Raju, Leu N Adrian, Senoo Makoto

Accelerated reproductive aging in females lacking a novel centromere protein SYCP2L

缺乏新型着丝粒蛋白SYCP2L的女性生殖衰老加速

Zhou, Jian; Stein, Paula; Leu, N Adrian; Chmátal, Lukáš; Xue, Jiangyang; Ma, Jun; Huang, Xiaoyan; Lampson, Michael A; Schultz, Richard M; Wang, P Jeremy