日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Iron deficiency induces maturation-dependent loss of pancreatic β-cells.

缺铁会导致胰腺β细胞成熟依赖性丢失。

Van Mulders Annelore, Willems Lien, Coenen Sophie, Bourgeois Stephanie, Yi Xiaoyan, Tong Yue, Leuckx Gunter, Heremans Yves, Pierreux Julie, Degroote Laure, Sawatani Toshiaki, Vinci Chiara, Ates Gamze, Massie Ann, Carlotti Françoise, de Koning Eelco, Mandrup-Poulsen Thomas, Zelinsky Clara, Goderis Steven, Ghesquière Bart, Scharfmann Raphael, Cnop Miriam, De Leu Nico, Staels Willem

Transient ER stress cell-autonomously promotes beta cell cycling in mice

瞬时内质网应激以细胞自主的方式促进小鼠β细胞周期。

Bourgeois, Stephanie; Van Mulders, Annelore; Heremans, Yves; Leuckx, Gunter; Willems, Lien; Coenen, Sophie; Degroote, Laure; Pierreux, Julie; Kancheva, Daliya; Scheyltjens, Isabelle; Movahedi, Kiavash; Carlotti, Françoise; de Koning, Eelco; Yi, Xiaoyan; Vinci, Chiara; Tong, Yue; Cnop, Miriam; Heimberg, Harry; De Leu, Nico; Staels, Willem

Verapamil and low-dose anti-mouse thymocyte globulin combination therapy stably reverses recent-onset type 1 diabetes in NOD mice by acting on the beta cell and immune axes.

维拉帕米和低剂量抗小鼠胸腺细胞球蛋白联合疗法通过作用于β细胞和免疫轴,稳定逆转NOD小鼠近期发病的1型糖尿病。

Degroote Laure, Martens Pieter-Jan, Viaene Marijke, Heremans Yves, Leuckx Gunter, Geukens Nick, De Leu Nico, Staels Willem, Mathieu Chantal, Gysemans Conny

Discovery and 3D imaging of a novel ΔNp63-expressing basal cell type in human pancreatic ducts with implications in disease

在人类胰腺导管中发现并进行三维成像,揭示了一种表达ΔNp63的新型基底细胞类型及其与疾病的关系

Martens, Sandrina; Coolens, Katarina; Van Bulck, Mathias; Arsenijevic, Tatjana; Casamitjana, Joan; Fernandez Ruiz, Angel; El Kaoutari, Abdessamad; Martinez de Villareal, Jaime; Madhloum, Hediel; Esni, Farzad; Heremans, Yves; Leuckx, Gunter; Heimberg, Harry; Bouwens, Luc; Jacquemin, Patrick; De Paep, Diedert Luc; In't Veld, Peter; D'Haene, Nicky; Bouchart, Christelle; Dusetti, Nelson; Van Laethem, Jean-Luc; Waelput, Wim; Lefesvre, Pierre; Real, Francisco X; Rovira, Meritxell; Rooman, Ilse

Retraction Note: Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice

撤稿声明:短暂的细胞因子治疗可诱导糖尿病小鼠腺泡细胞重编程并再生功能性β细胞数量。

Baeyens, Luc; Lemper, Marie; Leuckx, Gunter; De Groef, Sofie; Bonfanti, Paola; Stangé, Geert; Shemer, Ruth; Nord, Christoffer; Scheel, David W; Pan, Fong C; Ahlgren, Ulf; Gu, Guoqiang; Stoffers, Doris A; Dor, Yuval; Ferrer, Jorge; Gradwohl, Gerard; Wright, Christopher V E; Van de Casteele, Mark; German, Michael S; Bouwens, Luc; Heimberg, Harry

ROBO2 is a stroma suppressor gene in the pancreas and acts via TGF-β signalling

ROBO2是胰腺中的一种基质抑制基因,它通过TGF-β信号通路发挥作用。

Andreia V Pinho ,Mathias Van Bulck ,Lorraine Chantrill ,Mehreen Arshi ,Tatyana Sklyarova ,David Herrmann ,Claire Vennin ,David Gallego-Ortega ,Amanda Mawson ,Marc Giry-Laterriere ,Astrid Magenau ,Gunther Leuckx ,Luc Baeyens ,Anthony J Gill ,Phoebe Phillips ,Paul Timpson ,Andrew V Biankin ,Jianmin Wu ,Ilse Rooman

Inhibition of Cdk5 Promotes β-Cell Differentiation From Ductal Progenitors

抑制 Cdk5 可促进导管祖细胞向 β 细胞分化

Ka-Cheuk Liu, Gunter Leuckx, Daisuke Sakano, Philip A Seymour, Charlotte L Mattsson, Linn Rautio, Willem Staels, Yannick Verdonck, Palle Serup, Shoen Kume, Harry Heimberg, Olov Andersson

Semi-automated digital measurement as the method of choice for beta cell mass analysis

半自动数字测量是β细胞质量分析的首选方法

Coppens, Violette; Leuckx, Gunter; Heremans, Yves; Staels, Willem; Verdonck, Yannick; Baeyens, Luc; De Leu, Nico; Heimberg, Harry

Human multipotent adult progenitor cells enhance islet function and revascularisation when co-transplanted as a composite pellet in a mouse model of diabetes

人类多能成体祖细胞在糖尿病小鼠模型中以复合颗粒形式共移植时可增强胰岛功能和血管重建

João Paulo M C M Cunha, Gunter Leuckx, Peter Sterkendries, Hannelie Korf, Gabriela Bomfim-Ferreira, Lutgart Overbergh, Bart Vaes, Harry Heimberg, Conny Gysemans, Chantal Mathieu

The zinc finger transcription factor PW1/PEG3 restrains murine beta cell cycling

锌指转录因子PW1/PEG3抑制小鼠β细胞周期

Sojoodi, Mozhdeh; Stradiot, Leslie; Tanaka, Karo; Heremans, Yves; Leuckx, Gunter; Besson, Vanessa; Staels, Willem; Van de Casteele, Mark; Marazzi, Giovanna; Sassoon, David; Heimberg, Harry; Bonfanti, Paola