日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

IgM Anti-Ganglioside Binding and Complement Activation in an iPSC-Derived Motor Neuron Model for Multifocal Motor Neuropathy

在iPSC衍生运动神经元模型中，IgM抗神经节苷脂结合和补体激活在多灶性运动神经病中的作用

期刊:Neurology-Neuroimmunology & Neuroinflammation
影响因子:7.5
doi:10.1212/NXI.0000000000200482
Krijgsman, Daniëlle; Dijkxhoorn, Kim; de Zeeuw, Elisabeth; Bloemenkamp, Lauri M; Bos, Jeroen W; van Eijk, Ruben P A; Van de Walle, Inge; Huizinga, Ruth; Jacobs, Bart C; Leusen, Jeanette H W; Pasterkamp, R Jeroen; Hack, C Erik; Budding, Kevin; van der Pol, W Ludo
IgM
神经科学
免疫/内分泌
发表日期：2026
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Preclinical assessment of two FcγRI-specific antibodies that competitively inhibit immune complex-FcγRI binding to suppress autoimmune responses

对两种FcγRI特异性抗体进行临床前评估，这两种抗体通过竞争性抑制免疫复合物-FcγRI结合来抑制自身免疫反应。

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-65133-z
Tosca Holtrop ，Arianne M Brandsma ，Louris J Feitsma ，Steffen Krohn ，Petra Moerer ，Frederique van den Haak ，Anouk Versnel ，Leonie Voss ，Elsemieke M Passchier ，Maaike Nederend ，J H Marco Jansen ，Anouk G van Mourik ，Rolf T Urbanus ，Diane van der Woude ，Roger E G Schutgens ，Rene E M Toes ，Bert J C Janssen ，Anja Lux ，Kevin Budding ，Matthias Peipp ，Jeanette H W Leusen
免疫/内分泌
巨噬细胞
发表日期：2025
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Extracellular domain 1 of human FcγRI (CD64) identified as the binding site for anti-FcγRI antibodies

人FcγRI（CD64）的胞外结构域1被鉴定为抗FcγRI抗体的结合位点

期刊:MAbs
影响因子:7.3
doi:10.1080/19420862.2025.2580695
Holtrop, Tosca; Passchier, Elsemieke M; O'Toole, Sophie; Kraan, W Joost; Budding, Kevin; Leusen, Jeanette H W
CD6
CD64
发表日期：2025
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Anti-PD-1 treatment response is associated with the influx of circulating myeloid and T-cell subsets into the metastatic melanoma tumor microenvironment

抗PD-1治疗反应与循环髓系细胞和T细胞亚群流入转移性黑色素瘤肿瘤微环境有关。

期刊:British Journal of Cancer
影响因子:6.8
doi:10.1038/s41416-025-03137-8
Van Dam, S; Krijgsman, D; Küçükköse, E; Verdonschot, M E L; Amini, M; Blokx, W A M; Van Eijs, M J M; Verheijden, R J; Kranenburg, O; Suijkerbuijk, K P M; Leusen, J H W; Vercoulen, Y
黑色素瘤
肿瘤
T细胞
肿瘤免疫
T细胞
细胞生物学
肿瘤微环境
PD-1
免疫/内分泌
发表日期：2025
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High-plex imaging of hepatoblastoma and adjacent liver in pediatric patients reveals a predominant myeloid infiltrate expressing immune-checkpoints

对儿童肝母细胞瘤及其邻近肝组织进行高通量成像显示，以表达免疫检查点的髓系浸润为主。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-025-04164-3
Krijgsman, Daniëlle; Schubert, Stephanie A; Kraaier, Lianne J; Lu, Yuyan; van Avondt, Kristof; Verdonschot, Meggy E L; Leusen, Jeanette H W; van den Heuvel, Marius C; de Kleine, Ruben H; de Meijer, Vincent E; Kraal, Kathelijne C J; de Krijger, Ronald R; Zsiros, József; Peng, Weng Chuan; Vercoulen, Yvonne
细胞生物学
免疫/内分泌
发表日期：2025
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The Efficacy of Targeted Monoclonal IgA Antibodies Against Pancreatic Ductal Adenocarcinoma

靶向单克隆IgA抗体治疗胰腺导管腺癌的疗效

期刊:Cells
影响因子:5.1
doi:10.3390/cells14090632
Léon Raymakers ，Elsemieke M Passchier ，Meggy E L Verdonschot ，Mitchell Evers ，Chilam Chan ，Karel C Kuijpers ，G Mihaela Raicu ，I Quintus Molenaar ，Hjalmar C van Santvoort ，Karin Strijbis ，Martijn P W Intven ，Lois A Daamen ，Jeanette H W Leusen ，Patricia A Olofsen
肿瘤
IgA
肿瘤免疫
发表日期：2025
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Quantification of Signal Transduction Pathway Activity in Pancreatic Ductal Adenocarcinoma

胰腺导管腺癌信号转导通路活性的定量分析

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms262311385
Raymakers, Léon; Daamen, Lois A; Intven, Martijn P W; Leusen, Jeanette H W; Olofsen, Patricia A; van de Stolpe, Anja; Raymakers, Reinier A P
信号转导
肿瘤
肿瘤免疫
发表日期：2025
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Variations of heterometallic cores and magnetic properties in Co(iii)-Y/Ln isobutyrate clusters with N-butyldiethanolamine: from tetranuclear to octanuclear clusters

N-丁基二乙醇胺修饰的Co(iii)-Y/Ln异丁酸酯簇合物中异金属核和磁性的变化：从四核簇合物到八核簇合物

期刊:RSC Advances
影响因子:4.6
doi:10.1039/d5ra02513c
Stati, Dumitru; van Leusen, Jan; Kravtsov, Victor Ch; Chumakov, Yurii; Kögerler, Paul; Baca, Svetlana G
发表日期：2025
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Maternal Dietary Fiber Intake During Lactation and Human Milk Oligosaccharide Fucosylation: a PRIMA Birth Cohort Study

哺乳期母亲膳食纤维摄入量与人乳寡糖岩藻糖基化：一项PRIMA出生队列研究

期刊:Molecular Nutrition & Food Research
影响因子:4.2
doi:10.1002/mnfr.70165
Hellinga, Anneke H; Cajic, Samanta; Linde, Hanneke F; van Stigt, Arthur H; de Vries, Jeanne H M; Brouwer-Brolsma, Elske M; Hennig, René; Rapp, Erdmann; Mank, Marko; Stahl, Bernd; Kraneveld, Aletta D; Leusen, Jeanette H W; Bont, Louis; Van't Land, Belinda
Human
发表日期：2025
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Treatment of colorectal peritoneal metastases with oxaliplatin induces biomarkers predicting response to immune checkpoint blockade

奥沙利铂治疗结直肠癌腹膜转移可诱导产生预测免疫检查点阻断疗法疗效的生物标志物

期刊:Translational Oncology
影响因子:4.1
doi:10.1016/j.tranon.2025.102464
Constantinides, Alexander; Lansu, Nico; Mosen, Peter; Rauwerdink, Paulien; Strating, Esther; Völlmy, Franziska; Nederend, Maaike; Leusen, Jeanette H W; Rovers, Koen; Wassenaar, Emma; Lurvink, Robin; Altelaar, Maarten; Nienhuijs, Simon; Wiezer, Rene; Borel Rinkes, Inne H M; Boerma, Djamila; Kops, Geert J P L; de Hingh, Ignace; Kranenburg, Onno
肿瘤
肠癌
肿瘤免疫
免疫/内分泌
发表日期：2025
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