日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Corrigendum to "P53-independent partial restoration of the p53 pathway in tumors with mutated p53 through ATF4 transcriptional modulation by ERK1/2 and CDK9" [Neoplasia, volume 23 (2021) 304325]

对“通过 ERK1/2 和 CDK9 对 ATF4 转录的调控,在 p53 突变的肿瘤中实现 p53 通路的 P53 非依赖性部分恢复”的更正 [Neoplasia,第 23 卷(2021 年)304325]

Tian, Xiaobing; Ahsan, Nagib; Lulla, Amriti; Lev, Avital; Abbosh, Philip; Dicker, David T; Zhang, Shengliang; El-Deiry, Wafik S

Correction: Discovery and clinical introduction of first-in-class imipridone ONC201

更正:首创药物咪吡啶酮 ONC201 的发现和临床应用

Allen, Joshua E; Kline, C Leah B; Prabhu, Varun V; Wagner, Jessica; Ishizawa, Jo; Madhukar, Neel; Lev, Avital; Baumeister, Marie; Zhou, Lanlan; Lulla, Amriti; Stogniew, Martin; Schalop, Lee; Benes, Cyril; Kaufman, Howard L; Pottorf, Richard S; Nallaganchu, B Rao; Olson, Gary L; Al-Mulla, Fahd; Duvic, Madeleine; Wu, Gen Sheng; Dicker, David T; Talekar, Mala K; Lim, Bora; Elemento, Olivier; Oster, Wolfgang; Bertino, Joseph; Flaherty, Keith; Wang, Michael L; Borthakur, Gautam; Andreeff, Michael; Stein, Mark; El-Deiry, Wafik S

Preclinical evaluation of the imipridone family, analogs of clinical stage anti-cancer small molecule ONC201, reveals potent anti-cancer effects of ONC212.

对伊米普利酮家族(临床阶段抗癌小分子 ONC201 的类似物)的临床前评估显示,ONC212 具有强大的抗癌作用

Wagner Jessica, Kline Christina Leah, Ralff Marie D, Lev Avital, Lulla Amriti, Zhou Lanlan, Olson Gary L, Nallaganchu Bhaskara Rao, Benes Cyril H, Allen Joshua E, Prabhu Varun V, Stogniew Martin, Oster Wolfgang, El-Deiry Wafik S

Memory CD8⁺ T cells can outsource IFN-γ production but not cytolytic killing for antiviral protection

记忆性CD8⁺ T细胞可以外包IFN-γ的产生,但不能外包细胞溶解杀伤作用以提供抗病毒保护。

Remakus, Sanda; Rubio, Daniel; Lev, Avital; Ma, Xueying; Fang, Min; Xu, Ren-Huan; Sigal, Luis J

Compartmentalized MHC class I antigen processing enhances immunosurveillance by circumventing the law of mass action

MHC I类抗原的区室化加工通过规避质量作用定律来增强免疫监视。

Lev, Avital; Princiotta, Michael F; Zanker, Damian; Takeda, Kazuyo; Gibbs, James S; Kumagai, Chiharu; Waffarn, Elizabeth; Dolan, Brian P; Burgevin, Anne; Van Endert, Peter; Chen, Weisan; Bennink, Jack R; Yewdell, Jonathan W

Antibody-mediated targeting of human single-chain class I MHC with covalently linked peptides induces efficient killing of tumor cells by tumor or viral-specific cytotoxic T lymphocytes

利用抗体介导的靶向人单链I类MHC分子,通过共价连接的肽段诱导肿瘤或病毒特异性细胞毒性T淋巴细胞有效杀伤肿瘤细胞。

Oved, Kfir; Lev, Avital; Noy, Roy; Segal, Dina; Reiter, Yoram

Direct visualization of distinct T cell epitopes derived from a melanoma tumor-associated antigen by using human recombinant antibodies with MHC- restricted T cell receptor-like specificity

利用具有MHC限制性T细胞受体样特异性的重组人抗体,直接观察源自黑色素瘤肿瘤相关抗原的不同T细胞表位

Denkberg, Galit; Cohen, Cyril J; Lev, Avital; Chames, Patrick; Hoogenboom, Hennie R; Reiter, Yoram