Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction
对已知的歌舞伎综合征相关KDM6A变异体的分子力学和动力学模拟揭示了其功能障碍的潜在机制。
期刊:Orphanet Journal of Rare Diseases
影响因子:3.5
doi:10.1186/s13023-021-01692-w
Chi, Young-In; Stodola, Timothy J; De Assuncao, Thiago M; Leverence, Elise N; Tripathi, Swarnendu; Dsouza, Nikita R; Mathison, Angela J; Basel, Donald G; Volkman, Brian F; Smith, Brian C; Lomberk, Gwen; Zimmermann, Michael T; Urrutia, Raul