日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mutant KRAS Heterogeneity Shapes Nuclear Architecture During Pancreatic Cancer Initiation.

突变型KRAS异质性在胰腺癌发生过程中塑造核结构。

Pollin Gareth, Mathison Angela J, Leverence Elise N, De Assuncao Thiago Milech, Iovanna Juan, Hong Johnny C, Zimmermann Michael T, Urrutia Raul, Lomberk Gwen

Beyond structural bioinformatics for genomics with dynamics characterization of an expanded KRAS mutational landscape

超越基因组学的结构生物信息学,动态表征扩展的 KRAS 突变景观

Brian D Ratnasinghe, Neshatul Haque, Jessica B Wagenknecht, Davin R Jensen, Guadalupe K Valdivia Esparza, Elise N Leverence, Thiago Milech De Assuncao, Angela J Mathison, Gwen Lomberk, Brian C Smith, Brian F Volkman, Raul Urrutia, Michael T Zimmermann

Beyond Structural Bioinformatics for Genomics with Dynamics Characterization of an Expanded KRAS Mutational Landscape

超越结构生物信息学,通过动态表征扩展的KRAS突变图谱,探索基因组学的新途径

Ratnasinghe, Brian D; Haque, Neshatul; Wagenknecht, Jessica B; Jensen, Davin R; Esparza, Guadalupe V; Leverence, Elise N; De Assuncao, Thiago Milech; Mathison, Angela J; Lomberk, Gwen; Smith, Brian C; Volkman, Brian F; Urrutia, Raul; Zimmermann, Michael T

Outcomes of an integrated practice unit for vulnerable emergency department patients

针对急诊科弱势患者的综合诊疗单元的成效

Borde, Deepa; Agana-Norman, Denny Fe G; Leverence, Robert; Photos, Lorrie; Shuster, Jon; Lukose, Kiran; Pinkney, Jacqueline; Wright, Joy; Waxenberg, Lori; Allen, Brandon; Radhakrishnan, Nila S

The synaptosome-associated protein 23 (SNAP23) is necessary for proper myogenesis

突触体相关蛋白 23 (SNAP23) 是正常肌肉生成所必需的

Gabrielle M Gentile, Jennifer R Gamarra, Nichlas M Engels, R Eric Blue, Isabel Hoerr, Hannah J Wiedner, Emma R Hinkle, Jessica L Cote, Elise Leverence, Christine A Mills, Laura E Herring, Xianming Tan, Jimena Giudice

Structural bioinformatics enhances the interpretation of somatic mutations in KDM6A found in human cancers

结构生物信息学有助于解读在人类癌症中发现的KDM6A体细胞突变。

Chi, Young-In; Stodola, Timothy J; De Assuncao, Thiago M; Leverence, Elise N; Smith, Brian C; Volkman, Brian F; Mathison, Angela J; Lomberk, Gwen; Zimmermann, Michael T; Urrutia, Raul

KrasG12D induces changes in chromatin territories that differentially impact early nuclear reprogramming in pancreatic cells

KrasG12D诱导染色质区域发生改变,从而对胰腺细胞早期核重编程产生不同的影响。

Angela J Mathison # ,Romica Kerketta # ,Thiago Milech de Assuncao ,Elise Leverence ,Atefeh Zeighami ,Guillermo Urrutia ,Timothy J Stodola ,Marina Pasca di Magliano ,Juan L Iovanna ,Michael T Zimmermann ,Gwen Lomberk ,Raul Urrutia

Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics

使用基于证据的结构生物信息学增强对 935 个热点和非热点 RAS 变体的解释

Swarnendu Tripathi, Nikita R Dsouza, Angela J Mathison, Elise Leverence, Raul Urrutia, Michael T Zimmermann

Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction

对已知的歌舞伎综合征相关KDM6A变异体的分子力学和动力学模拟揭示了其功能障碍的潜在机制。

Chi, Young-In; Stodola, Timothy J; De Assuncao, Thiago M; Leverence, Elise N; Tripathi, Swarnendu; Dsouza, Nikita R; Mathison, Angela J; Basel, Donald G; Volkman, Brian F; Smith, Brian C; Lomberk, Gwen; Zimmermann, Michael T; Urrutia, Raul

Correction to: Molecular mechanics and dynamic simulations of well-known Kabuki syndrome-associated KDM6A variants reveal putative mechanisms of dysfunction

更正:分子力学和动力学模拟揭示了已知的歌舞伎综合征相关KDM6A变异体的功能障碍的潜在机制

Chi, Young-In; Stodola, Timothy J; De Assuncao, Thiago M; Leverence, Elise N; Tripathi, Swarnendu; Dsouza, Nikita R; Mathison, Angela J; Basel, Donald G; Volkman, Brian F; Smith, Brian C; Lomberk, Gwen; Zimmermann, Michael T; Urrutia, Raul