日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Research towards selective inhibition of the CLK3 kinase

针对CLK3激酶选择性抑制的研究

Singh, Vinay Kumar; Justaud, Frédéric; Brahmaiah, Dabbugoddu; Kumar, Nangunoori Sampath; Baratte, Blandine; Robert, Thomas; Bach, Stéphane; Reddy, Chada Raji; Levoin, Nicolas; Grée, René L

MMP7 cleavage of amino-terminal CD95 death receptor switches signaling toward non-apoptotic pathways

MMP7 切割氨基末端 CD95 死亡受体,将信号传导转向非凋亡途径

Shoji F Kenji, Keerthi Kurma, Brigitte Collet, Christelle Oblet, Laure Debure, Carmelo Di Primo, Laëtitia Minder, Franck Vérité, Yannic Danger, Mickael Jean, Aubin Penna, Nicolas Levoin, Patrick Legembre

Structure Activity Relationship Studies around DB18, a Potent and Selective Inhibitor of CLK Kinases

针对 CLK 激酶的强效选择性抑制剂 DB18 的构效关系研究

Dabbugoddu Brahmaiah, Anagani Kanaka Durga Bhavani, Pasula Aparna, Nangunoori Sampath Kumar, Hélène Solhi, Rémy Le Guevel, Blandine Baratte, Thomas Robert, Sandrine Ruchaud, Stéphane Bach, Surender Singh Jadav, Chada Raji Reddy, Paul Mosset, Nicolas Gouault, Nicolas Levoin, René Grée

CD95 Structure, Aggregation and Cell Signaling

CD95的结构、聚集和细胞信号传导

Levoin, Nicolas; Jean, Mickael; Legembre, Patrick

Targeting PUMA/Bcl-xL interaction by new specific compounds to unleash apoptotic process in cancer cells

通过新的特异性化合物靶向 PUMA/Bcl-xL 相互作用来引发癌细胞凋亡过程

Appala Venkata Ramana Murthy, Vennu Narendar, Nangunoori Sampath Kumar, Pasula Aparna, Anagani Kanaka Durga Bhavani, Fabien Gautier, Sophie Barillé-Nion, Philippe Juin, Paul Mosset, René Grée, Nicolas Levoin

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice

CD95 介导的钙信号促进 T 辅助细胞 17 转运至易患狼疮的小鼠的发炎器官

Amanda Poissonnier, Doriane Sanséau, Matthieu Le Gallo, Marine Malleter, Nicolas Levoin, Roselyne Viel, Lucie Morere, Aubin Penna, Patrick Blanco, Alain Dupuy, Florence Poizeau, Alain Fautrel, Julien Seneschal, Florence Jouan, Jerome Ritz, Edouard Forcade, Nathalie Rioux, Cécile Contin-Bordes, Thoma

Homology Model Versus X-ray Structure in Receptor-based Drug Design: A Retrospective Analysis with the Dopamine D3 Receptor

受体药物设计中同源模型与X射线晶体结构的比较:以多巴胺D3受体为例的回顾性分析

Levoin, Nicolas; Calmels, Thierry; Krief, Stéphane; Danvy, Denis; Berrebi-Bertrand, Isabelle; Lecomte, Jeanne-Marie; Schwartz, Jean-Charles; Capet, Marc