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Differential activity and selectivity of N-terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors

N端修饰的CXCL12趋化因子在CXCR4和ACKR3受体上的差异活性和选择性

Jaracz-Ros, Agnieszka; Bernadat, Guillaume; Cutolo, Pasquale; Gallego, Carmen; Gustavsson, Martin; Cecon, Erika; Baleux, Françoise; Kufareva, Irina; Handel, Tracy M; Bachelerie, Françoise; Levoye, Angélique

CXCR4

High-Density Lipoprotein Therapy in Stroke: Evaluation of Endothelial SR-BI-Dependent Neuroprotective Effects

高密度脂蛋白治疗中风：评估内皮 SR-BI 依赖性神经保护作用

期刊:International Journal of Molecular Sciences

影响因子:0.7

doi:10.3390/ijms22010106

Alexy Tran-Dinh, Angélique Levoye, David Couret, Lauriane Galle-Treger, Martine Moreau, Sandrine Delbosc, Camille Hoteit, Philippe Montravers, Pierre Amarenco, Thierry Huby, Olivier Meilhac

A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate

结合 SNAP 标签标记、扩散增强共振能量转移和高发射性铽穴状化合物的广谱 G 蛋白偶联受体内化试验

期刊:Frontiers in Endocrinology

影响因子:

doi:10.3389/fendo.2015.00167

Angélique Levoye, Jurriaan M Zwier, Agnieszka Jaracz-Ros, Laurence Klipfel, Martin Cottet, Damien Maurel, Sara Bdioui, Karl Balabanian, Laurent Prézeau, Eric Trinquet, Thierry Durroux, Françoise Bachelerie

其它

发表日期：2015

文献求助收藏

Low levels of low-density lipoprotein-C associated with proprotein convertase subtilisin kexin 9 inhibition do not increase the risk of hemorrhagic transformation

与前蛋白转化酶枯草杆菌蛋白酶 kexin 9 抑制相关的低密度脂蛋白 C 水平不会增加出血性转化的风险

期刊:Stroke

影响因子:7.8

doi:10.1161/STROKEAHA.114.005958

Alexy Tran-Dinh, Angélique Levoye, Gilles Lambert, Liliane Louedec, Clément Journé, Olivier Meilhac, Pierre Amarenco

微生物学

发表日期：2014

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CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome

CXCR4 二聚化和 β-arrestin 介导的信号传导导致 WHIM 综合征中对 CXCL12 的趋化作用增强

期刊:Blood

影响因子:21

doi:10.1182/blood-2007-07-102103

Bernard Lagane, Ken Y C Chow, Karl Balabanian, Angélique Levoye, Julie Harriague, Thierry Planchenault, Françoise Baleux, Nathalie Gunera-Saad, Fernando Arenzana-Seisdedos, Françoise Bachelerie

信号转导

发表日期：2008

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Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling

对WHIM综合征患者的白细胞分析揭示了GRK3在CXCR4信号传导中的关键作用

期刊:Journal of Clinical Investigation

影响因子:13.6

doi:10.1172/JCI33187

Balabanian, Karl; Levoye, Angélique; Klemm, Lysiane; Lagane, Bernard; Hermine, Olivier; Harriague, Julie; Baleux, Françoise; Arenzana-Seisdedos, Fernando; Bachelerie, Françoise

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins

CXCL12gamma 趋化因子表现出前所未有的结构和功能特性，使其成为趋化蛋白的典范

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0002543

Patricia Rueda, Karl Balabanian, Bernard Lagane, Isabelle Staropoli, Ken Chow, Angelique Levoye, Cedric Laguri, Rabia Sadir, Thierry Delaunay, Elena Izquierdo, Jose Luis Pablos, Elena Lendinez, Antonio Caruz, Diego Franco, Françoise Baleux, Hugues Lortat-Jacob, Fernando Arenzana-Seisdedos

信号转导

发表日期：2008

文献求助收藏

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

孤儿受体GPR50通过异二聚化特异性抑制MT1褪黑素受体的功能。

期刊:EMBO Journal

影响因子:8.3

doi:10.1038/sj.emboj.7601193

Levoye, Angélique; Dam, Julie; Ayoub, Mohammed A; Guillaume, Jean-Luc; Couturier, Cyril; Delagrange, Philippe; Jockers, Ralf

信号转导

发表日期：2006

文献求助收藏

Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers

孤儿G蛋白偶联受体是否具有配体非依赖性功能？来自受体异二聚体的新见解

期刊:EMBO Reports

影响因子:6.2

doi:10.1038/sj.embor.7400838

Levoye, Angélique; Dam, Julie; Ayoub, Mohammed A; Guillaume, Jean-Luc; Jockers, Ralf

信号转导

发表日期：2006

文献求助收藏

Emerging Roles of the Atypical Chemokine Receptor 3 (ACKR3) in Cardiovascular Diseases

非典型趋化因子受体3 (ACKR3) 在心血管疾病中的新兴作用

Differential activity and selectivity of N-terminal modified CXCL12 chemokines at the CXCR4 and ACKR3 receptors

N端修饰的CXCL12趋化因子在CXCR4和ACKR3受体上的差异活性和选择性

High-Density Lipoprotein Therapy in Stroke: Evaluation of Endothelial SR-BI-Dependent Neuroprotective Effects

高密度脂蛋白治疗中风：评估内皮 SR-BI 依赖性神经保护作用

A Broad G Protein-Coupled Receptor Internalization Assay that Combines SNAP-Tag Labeling, Diffusion-Enhanced Resonance Energy Transfer, and a Highly Emissive Terbium Cryptate

结合 SNAP 标签标记、扩散增强共振能量转移和高发射性铽穴状化合物的广谱 G 蛋白偶联受体内化试验

Low levels of low-density lipoprotein-C associated with proprotein convertase subtilisin kexin 9 inhibition do not increase the risk of hemorrhagic transformation

与前蛋白转化酶枯草杆菌蛋白酶 kexin 9 抑制相关的低密度脂蛋白 C 水平不会增加出血性转化的风险

CXCR4 dimerization and beta-arrestin-mediated signaling account for the enhanced chemotaxis to CXCL12 in WHIM syndrome

CXCR4 二聚化和 β-arrestin 介导的信号传导导致 WHIM 综合征中对 CXCL12 的趋化作用增强

Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signaling

对WHIM综合征患者的白细胞分析揭示了GRK3在CXCR4信号传导中的关键作用

The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins

CXCL12gamma 趋化因子表现出前所未有的结构和功能特性，使其成为趋化蛋白的典范

The orphan GPR50 receptor specifically inhibits MT1 melatonin receptor function through heterodimerization

孤儿受体GPR50通过异二聚化特异性抑制MT1褪黑素受体的功能。

Do orphan G-protein-coupled receptors have ligand-independent functions? New insights from receptor heterodimers

孤儿G蛋白偶联受体是否具有配体非依赖性功能？来自受体异二聚体的新见解