日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Results of a Large-Scale Study of the Binding of 50 Type II Inhibitors to 348 Kinases: The Role of Protein Reorganization

一项大规模研究50种II型抑制剂与348种激酶结合的结果:蛋白质重组的作用

Vardanyan, Vardan H; Haldane, Allan; Hwang, Howook; Coskun, Dilek; Lihan, Muyun; Miller, Edward B; Friesner, Richard A; Levy, Ronald M

Predicting water at the protein interface in cryo-EM structures from MD-excess chemical potential

利用分子动力学模拟过量化学势预测冷冻电镜结构中蛋白质界面处的水分子

Sun, Qinfang; Aiyer, Sriram; Biswas, Avik; Haldane, Allan; Chatterjee, Sompriya; Matubayasi, Nobuyuki; Lyumkis, Dmitry; Levy, Ronald M

Toward Reconciling the Standard Binding Free Energy of Lenacapavir to HIV-1 Capsid with Experiment: Thermodynamic Effects of Solvent Buffer and Ligand Reorganization

为使Lenacapavir与HIV-1衣壳的标准结合自由能与实验结果相符:溶剂缓冲液和配体重组的热力学效应

Sun, Qinfang; Gallicchio, Emilio; Levy, Ronald; Deng, Nanjie

Benchmarking free energy calculations: Analysis of single and double mutations across two simulation software platforms for two protein systems

自由能计算基准测试:分析两种蛋白质系统在两种模拟软件平台上的单突变和双突变情况

Gupta, Shivani; Sun, Qinfang; Levy, Ronald M

Results of a large scale study of the binding of 50 type II inhibitors to 348 kinases: The role of protein reorganization

一项大规模研究50种II型抑制剂与348种激酶结合的结果:蛋白质重组的作用

Vardanyan, Vardan H; Haldane, Allan; Hwang, Howook; Coskun, Dilek; Lihan, Muyun; Miller, Edward B; Friesner, Richard A; Levy, Ronald M

Co-occurrence of clonally related follicular lymphoma and histiocytic sarcoma

克隆相关的滤泡性淋巴瘤和组织细胞肉瘤的共存

Haebe, Sarah; Czerwinski, Debra K; Sathe, Anuja; Grimes, Susan M; Chen, Tianqi; Suarez, Carlos J; Martin, Brock; Ji, Hanlee P; Levy, Ronald; Shree, Tanaya

A Phase I Clinical Trial Adding OX40 Agonism to In Situ Therapeutic Cancer Vaccination in Patients with Low-Grade B-cell Lymphoma Highlights Challenges in Translation from Mouse to Human Studies.

一项针对低级别 B 细胞淋巴瘤患者的 I 期临床试验,将 OX40 激动剂添加到原位治疗性癌症疫苗中,凸显了从小鼠研究到人体研究转化过程中面临的挑战

Shree Tanaya, Czerwinski Debra, Haebe Sarah, Sathe Anuja, Grimes Sue, Martin Brock, Ozawa Michael, Hoppe Richard, Ji Hanlee, Levy Ronald

Development of an in situ CAR-T cell protocol through optical and PSMA-targeted PET imaging.

通过光学和PSMA靶向PET成像开发原位CAR-T细胞方案

Zhang Nisi, Seo Jai Woong, Robinson Elise, Rivera-Rodriguez Angelie, Wang James, Guo Yutong, Czerwinski Debra K, Kim Ha Rin, Tumbale Spencer K, Raie Marina N, Jan Basit L, Engudar Gokce, Sallets Adrienne, Minn Il, Pomper Martin G, Levy Ronald, Ferrara Katherine W

Autophagy-related 7 (ATG7) regulates food intake and liver health during asparaginase exposure

自噬相关 7 (ATG7) 在天冬酰胺酶暴露期间调节食物摄入和肝脏健康

Brian A Zalma, Maria Ibrahim, Flavio C Rodriguez-Polanco, Chintan T Bhavsar, Esther M Rodriguez, Eduardo Cararo-Lopes, Saad A Farooq, Jordan L Levy, Ronald C Wek, Eileen White, Tracy G Anthony

Predicting side chain conformations in folded proteins by AlphaFold: Perspective and challenges

利用AlphaFold预测折叠蛋白侧链构象:展望与挑战

Maisuradze, Gia G; Thakur, Abhishek; Khatri, Kisan; Haldane, Allan; Levy, Ronald M