日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy.

抗PD-1治疗后,与HIV病毒库相关的先天性抗病毒和免疫功能会衰退。

Talla Aarthi, Azevedo Joao L L C, Latif Muhammad Bilal, Enriquez Ana B, Sanchez Gabriela Pacheco, Pelletier Adam N, Bal Saswat Kumar, Kumari Sangeeta, Schuch Viviane, Ghneim Khader, Rhodes Ajantha, Maldarelli Frank, Yarchoan Robert, Lurain Kathryn, Ramaswami Ramya, Sharon Elad, Hess Bruce W, D'Amico Leonard, Martinez-Picado Javier, Chomont Nicolas, Lewin Sharon R, Deeks Steven G, Fling Steven P, Cheever Martin A, Uldrick Thomas S, Sharma Ashish A, Sekaly Rafick-Pierre

Methaneseleninic acid, a circadian-modulating agent, reactivates latent HIV-1 infection without cellular activation or proliferation.

甲硒酸是一种昼夜节律调节剂,它能重新激活潜伏的 HIV-1 感染,而无需细胞活化或增殖。

Stern Jared, Shepherd Rory A, Kim Youry, Tumpach Carolin, Amos Kirsten E, Williams Oscar H Lloyd, Varshney Swati, King Hannah A D, Rhodes Ajantha, Lewin Sharon R, Roche Michael

Immunotherapy and impact on tissue reservoirs

免疫疗法及其对组织库的影响

King, Hannah A D; Angelovich, Thomas A; Moso, Michael A; Pascoe, Rachel D; Churchill, Melissa J; Lewin, Sharon R

The effect of combining HIV latency reversal with inhibition of phosphoinositide-3 kinases or B-cell lymphoma-2 on the HIV reservoir

将逆转 HIV 潜伏期与抑制磷脂酰肌醇-3 激酶或 B 细胞淋巴瘤-2 联合使用对 HIV 病毒库的影响

Kim, Youry; Anderson, Jenny L; Tumpach, Carolin; Solomon, Ajantha; Ong, Jesslyn; Tanaka, Kiho; Zerbato, Jennifer M; Tan, Tania; Teh, Charis E; Gray, Daniel H D; Arandjelovic, Philip; McMahon, James; Meagher, Niamh; Price, David; Pellegrini, Marc; Roche, Michael; Lewin, Sharon R

Efficient mRNA delivery to resting T cells to reverse HIV latency.

将mRNA高效递送至静息T细胞以逆转HIV潜伏期

Cevaal Paula M, Kan Stanislav, Fisher Bridget M, Moso Michael A, Tan Abigail, Liu Haiyin, Ali Abdalla, Tanaka Kiho, Shepherd Rory A, Kim Youry, Ong Jesslyn, Furtado Denzil L, Holz Marvin, Purcell Damian F J, Casan Joshua M L, Payne Thomas, Zhao Wei, Fareh Mohamed, McMahon James H, Deeks Steven G, Hoh Rebecca, Telwatte Sushama, Pouton Colin W, Johnston Angus P R, Caruso Frank, Symons Jori, Lewin Sharon R, Roche Michael

HLA-B*15:01-positive severe COVID-19 patients lack CD8(+) T cell pools with highly expanded public clonotypes

HLA-B*15:01阳性的重症COVID-19患者缺乏具有高度扩增的公共克隆型的CD8(+) T细胞库

Rowntree, Louise C; Allen, Lilith F; Hagen, Ruth R; McQuilten, Hayley A; Quadeer, Ahmed A; Chaurasia, Priyanka; Kaewpreedee, Prathanporn; Lee, Kelly W K; Cohen, Carolyn A; Petersen, Jan; Littler, Dene R; Habel, Jennifer R; Zhang, Wuji; Cheng, Samuel M S; Chan, Ken Ka Pang; Kwok, Janette S Y; Leung, Kathy S M; Wu, Joseph T; Lee, Cheuk-Kwong; Davies, Jane; Pannaraj, Pia S; Kaity Allen, E; Thomas, Paul G; Tosif, Shidan; Crawford, Nigel W; Lappas, Martha; Thevarajan, Irani; Lewin, Sharon R; Kent, Stephen J; Juno, Jennifer A; Bond, Katherine A; Williamson, Deborah A; Holmes, Natasha E; Smibert, Olivia C; Gordon, Claire L; Trubiano, Jason A; Kotsimbos, Tom C; Cheng, Allen C; Efstathiou, Claudia; Turtle, Lance; Thwaites, Ryan S; Brightling, Christopher E; Rossjohn, Jamie; McKay, Matthew R; Tian, Jinmin; Liu, William Jun; Gao, George Fu; Xu, Jianqing; Sonehara, Kyuto; Ishii, Ken J; Namkoong, Ho; Okada, Yukinori; Peiris, Malik; Hui, David S C; Poon, Leo L M; Doherty, Peter C; Nguyen, Thi H O; Valkenburg, Sophie A; Kedzierska, Katherine

Mechanism for evolution of diverse autologous antibodies upon broadly neutralizing antibody therapy of people with HIV

HIV感染者接受广谱中和抗体治疗后,自身抗体多样性演变的机制

Kannan, Deepti; Wang, Eric; Deeks, Steven G; Lewin, Sharon R; Chakraborty, Arup K

Opportunities and challenges for hepatitis B cure in people living with HIV and hepatitis B virus

艾滋病毒和乙肝病毒合并感染者治愈乙肝的机遇与挑战

Singh, Kasha P; Audsley, Jennifer; Zhao, Wei; Lewin, Sharon R

Hepatitis B surface antigen is upregulated by HIV Tat in an HIV-hepatitis B virus co-infection model system.

在 HIV-乙型肝炎病毒共感染模型系统中,乙型肝炎表面抗原受 HIV Tat 上调

Zhao Wei, Singh Kasha, Sozzi Vitini, Cevaal Paula, Rossello Fernando J, Martelotto Luciano, Zerbato Jennifer M, Rhodes Ajantha, Powell David R, Schröder Jan, Anderson Jenny, Tumpach Carolin, Fong Danielle, Revill Peter, Crane Megan, Grimmond Sean, Roche Michael, Audsley Jennifer, Lewin Sharon R

The impact of acute stress on the HIV reservoir: a prospective interventional trial

急性应激对HIV病毒库的影响:一项前瞻性干预试验

Stern, Jared; Roche, Michael; Shepherd, Rory; Hartogensis, Wendy; Moran, Patricia; Cockerham, Leslie; Saraya, Nadia; Rhodes, Ajantha; Cameron, Paul U; Chang, Judy J; Kumar, Nitasha; Mendes, Wendy B; Deeks, Steven G; Hecht, Frederick M; Lewin, Sharon R