Clinical MDR1 inhibitors enhance Smac-mimetic bioavailability to kill murine LSCs and improve survival in AML models.
临床 MDR1 抑制剂可增强 Smac 模拟物的生物利用度，从而杀死小鼠 LSC 并提高 AML 模型中的生存率
期刊:Blood Advances
影响因子:7.1
doi:10.1182/bloodadvances.2020001576
Morrish Emma, Copeland Anthony, Moujalled Donia M, Powell Jason A, Silke Natasha, Lin Ann, Jarman Kate E, Sandow Jarrod J, Ebert Gregor, Mackiewicz Liana, Beach Jessica A, Christie Elizabeth L, Lewis Alexander C, Pomilio Giovanna, Fischer Karla C, MacPherson Laura, Bowtell David D L, Webb Andrew I, Pellegrini Marc, Dawson Mark A, Pitson Stuart M, Wei Andrew H, Silke John, Brumatti Gabriela
