日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Engineered protein-small molecule conjugates empower selective enzyme inhibition.

工程化蛋白质-小分子偶联物可实现选择性酶抑制

Lewis Andrew K, Harthorn Abbigael, Johnson Sadie M, Lobb Roy R, Hackel Benjamin J

Ubr3, a Novel Modulator of Hh Signaling Affects the Degradation of Costal-2 and Kif7 through Poly-ubiquitination

Ubr3,一种新型的Hh信号调节剂,通过多泛素化影响Costal-2和Kif7的降解

Tongchao Li, Junkai Fan, Bernardo Blanco-Sánchez, Nikolaos Giagtzoglou, Guang Lin, Shinya Yamamoto, Manish Jaiswal, Kuchuan Chen, Jie Zhang, Wei Wei, Michael T Lewis, Andrew K Groves, Monte Westerfield, Jianhang Jia, Hugo J Bellen

Open and closed conformations of the isolated transmembrane domain of death receptor 5 support a new model of activation

死亡受体5分离的跨膜结构域的开放和封闭构象支持一种新的激活模型。

Lewis, Andrew K; James, Zachary M; McCaffrey, Jesse E; Braun, Anthony R; Karim, Christine B; Thomas, David D; Sachs, Jonathan N

The methionine-aromatic motif plays a unique role in stabilizing protein structure

甲硫氨酸芳香族基序在稳定蛋白质结构中起着独特的作用。

Valley, Christopher C; Cembran, Alessandro; Perlmutter, Jason D; Lewis, Andrew K; Labello, Nicholas P; Gao, Jiali; Sachs, Jonathan N