日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

BMP signalling in colorectal cancer: losing the yin to WNTs yang

结直肠癌中的BMP信号通路:阴向WNTs阳的转变

Clarkson, Eloise; Lewis, Annabelle

BMP antagonist CHRDL2 enhances the cancer stem-cell phenotype and increases chemotherapy resistance in colorectal cancer.

BMP拮抗剂CHRDL2增强癌症干细胞表型,并增加结直肠癌的化疗耐药性。

Clarkson Eloise, Lewis Annabelle

Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis

功能分析揭示了子宫内膜癌发生过程中驱动基因的协同作用和新的机制

Brown, Matthew; Leon, Alicia; Kedzierska, Katarzyna; Moore, Charlotte; Belnoue-Davis, Hayley L; Flach, Susanne; Lydon, John P; DeMayo, Francesco J; Lewis, Annabelle; Bosse, Tjalling; Tomlinson, Ian; Church, David N

Therapeutic Potential of Protein Tyrosine Kinase 6 in Colorectal Cancer

蛋白酪氨酸激酶6在结直肠癌中的治疗潜力

Jerin, Samanta; Harvey, Amanda J; Lewis, Annabelle

Correction to: The MLH1 polymorphism rs1800734 and risk of endometrial cancer with microsatellite instability

更正:MLH1多态性rs1800734与微卫星不稳定性相关的子宫内膜癌风险

Russell, Holly; Kedzierska, Katarzyna; Buchanan, Daniel D; Thomas, Rachael; Tham, Emma; Mints, Miriam; Keränen, Anne; Giles, Graham G; Southey, Melissa C; Milne, Roger L; Tomlinson, Ian; Church, David; Spurdle, Amanda B; O'Mara, Tracy A; Lewis, Annabelle

CRISPR-Cas9 Causes Chromosomal Instability and Rearrangements in Cancer Cell Lines, Detectable by Cytogenetic Methods

CRISPR-Cas9 可导致癌细胞系染色体不稳定和重排,可通过细胞遗传学方法检测。

Rayner, Emily; Durin, Mary-Anne; Thomas, Rachael; Moralli, Daniela; O'Cathail, Sean M; Tomlinson, Ian; Green, Catherine M; Lewis, Annabelle

Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer

骨形态发生蛋白和Notch信号通路在预后不良的间质型结直肠癌中的相互作用

Irshad, Shazia; Bansal, Mukesh; Guarnieri, Paolo; Davis, Hayley; Al Haj Zen, Ayman; Baran, Brygida; Pinna, Claudia Maria Assunta; Rahman, Haseeb; Biswas, Sujata; Bardella, Chiara; Jeffery, Rosemary; Wang, Lai Mun; East, James Edward; Tomlinson, Ian; Lewis, Annabelle; Leedham, Simon John

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

Wnt信号通路和干细胞数量的基础梯度影响人和小鼠肠道内区域肿瘤的分布。

Leedham, Simon J; Rodenas-Cuadrado, Pedro; Howarth, Kimberley; Lewis, Annabelle; Mallappa, Sreelakshmi; Segditsas, Stefania; Davis, Hayley; Jeffery, Rosemary; Rodriguez-Justo, Manuel; Keshav, Satish; Travis, Simon P L; Graham, Trevor A; East, James; Clark, Susan; Tomlinson, Ian P M

Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1

遗传性混合性息肉综合征是由上游40 kb的重复序列引起的,该重复序列导致BMP拮抗剂GREM1的表达增加和异位表达。

Jaeger, Emma; Leedham, Simon; Lewis, Annabelle; Segditsas, Stefania; Becker, Martin; Cuadrado, Pedro Rodenas; Davis, Hayley; Kaur, Kulvinder; Heinimann, Karl; Howarth, Kimberley; East, James; Taylor, Jenny; Thomas, Huw; Tomlinson, Ian

The C-terminus of Apc does not influence intestinal adenoma development or progression.

Apc 的 C 端不影响肠道腺瘤的发生或发展

Lewis Annabelle, Davis Hayley, Deheragoda Maesha, Pollard Patrick, Nye Emma, Jeffery Rosemary, Segditsas Stefania, East Philip, Poulsom Richard, Stamp Gordon, Wright Nicholas, Tomlinson Ian