日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Formulation and characterization of poly(propylacrylic acid)/poly(lactic-co-glycolic acid) blend microparticles for pH-dependent membrane disruption and cytosolic delivery

聚(丙基丙烯酸)/聚(乳酸-乙醇酸)共混微粒的配方和表征,用于 pH 依赖性膜破坏和细胞质递送

Lawrence P Fernando, Jamal S Lewis, Brian C Evans, Craig L Duvall, Benjamin G Keselowsky

mTORC2 Signaling Drives the Development and Progression of Pancreatic Cancer

mTORC2信号通路驱动胰腺癌的发生发展

Driscoll, David R; Karim, Saadia A; Sano, Makoto; Gay, David M; Jacob, Wright; Yu, Jun; Mizukami, Yusuke; Gopinathan, Aarthi; Jodrell, Duncan I; Evans, T R Jeffry; Bardeesy, Nabeel; Hall, Michael N; Quattrochi, Brian J; Klimstra, David S; Barry, Simon T; Sansom, Owen J; Lewis, Brian C; Morton, Jennifer P

Activation of WNT/β-Catenin Signaling Enhances Pancreatic Cancer Development and the Malignant Potential Via Up-regulation of Cyr61

WNT/β-catenin信号通路的激活通过上调Cyr61增强胰腺癌的发展和恶性潜能

Sano, Makoto; Driscoll, David R; DeJesus-Monge, Wilfredo E; Quattrochi, Brian; Appleman, Victoria A; Ou, Jianhong; Zhu, Lihua Julie; Yoshida, Nao; Yamazaki, Shintaro; Takayama, Tadatoshi; Sugitani, Masahiko; Nemoto, Norimichi; Klimstra, David S; Lewis, Brian C

Activated wnt signaling in stroma contributes to development of pancreatic mucinous cystic neoplasms

基质中激活的Wnt信号通路促进胰腺黏液性囊性肿瘤的发生发展。

Sano, Makoto; Driscoll, David R; De Jesus-Monge, Wilfredo E; Klimstra, David S; Lewis, Brian C

Specific requirement of Gli transcription factors in Hedgehog-mediated intestinal development

Gli转录因子在Hedgehog介导的肠道发育中的特定需求

Huang, He; Cotton, Jennifer L; Wang, Yang; Rajurkar, Mihir; Zhu, Lihua J; Lewis, Brian C; Mao, Junhao

Functional activity of RLIM/Rnf12 is regulated by phosphorylation-dependent nucleocytoplasmic shuttling

RLIM/Rnf12的功能活性受磷酸化依赖的核质穿梭调控

Jiao, Baowei; Taniguchi-Ishigaki, Naoko; Güngör, Cenap; Peters, Marvin A; Chen, Ya-Wen; Riethdorf, Sabine; Drung, Alexander; Ahronian, Leanne G; Shin, Jongdae; Pagnis, Rachna; Pantel, Klaus; Tachibana, Taro; Lewis, Brian C; Johnsen, Steven A; Bach, Ingolf

KRAS(G12D)- and BRAF(V600E)-induced transformation of murine pancreatic epithelial cells requires MEK/ERK-stimulated IGF1R signaling

KRAS(G12D)和BRAF(V600E)诱导的小鼠胰腺上皮细胞转化需要MEK/ERK刺激的IGF1R信号传导

Appleman, Victoria A; Ahronian, Leanne G; Cai, JiuFeng; Klimstra, David S; Lewis, Brian C

Differential roles of insulin-like growth factor receptor- and insulin receptor-mediated signaling in the phenotypes of hepatocellular carcinoma cells.

胰岛素样生长因子受体和胰岛素受体介导的信号传导在肝细胞癌细胞表型中的不同作用

Chen Ya-Wen, Boyartchuk Victor, Lewis Brian C

p19Arf inhibits the invasion of hepatocellular carcinoma cells by binding to C-terminal binding protein

p19Arf通过与C端结合蛋白结合来抑制肝细胞癌细胞的侵袭。

Chen, Ya-Wen; Paliwal, Seema; Draheim, Kyle; Grossman, Steven R; Lewis, Brian C

Trp53 deletion stimulates the formation of metastatic pancreatic tumors

Trp53缺失会促进转移性胰腺肿瘤的形成。

Morton, Jennifer P; Klimstra, David S; Mongeau, Michelle E; Lewis, Brian C