日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Structural and mechanistic insights into herpesvirus helicase-primase and its therapeutic inhibitors

疱疹病毒解旋酶-引物酶及其治疗性抑制剂的结构和机制研究

Yao, Qing; Mercier, Alexandre; Nayak, Arabinda; May, Lindsey; Ho, Pui Yan; Lewis-Ballester, Ariel; Nair, Varsha; Sapre, Annapurna; Aeschbacher, Thomas; Mukherjee, Jit; Richards, Christopher; Mateo, Roberto; Cho, Aesop; Lansdon, Eric; Yu, Xinchao

Conformational Plasticity in Human Heme-Based Dioxygenases

人类血红素基双加氧酶的构象可塑性

Khoa N Pham, Ariel Lewis-Ballester, Syun-Ru Yeh

Characterization of the structural determinants of the ubiquitin-dependent proteasomal degradation of human hepatic tryptophan 2,3-dioxygenase

人类肝脏色氨酸 2,3-双加氧酶泛素依赖性蛋白酶体降解的结构决定因素的表征

Yi Liu, Sung-Mi Kim, YongQiang Wang, Shay Karkashon, Ariel Lewis-Ballester, Syun-Ru Yeh, Maria Almira Correia

Diaryl hydroxylamines as pan or dual inhibitors of indoleamine 2,3-dioxygenase-1, indoleamine 2,3-dioxygenase-2 and tryptophan dioxygenase

二芳基羟胺类化合物可作为吲哚胺2,3-双加氧酶-1、吲哚胺2,3-双加氧酶-2和色氨酸双加氧酶的泛抑制剂或双重抑制剂。

Winters, Maria; DuHadaway, James B; Pham, Khoa N; Lewis-Ballester, Ariel; Badir, Shorouk; Wai, Jenny; Sheikh, Eesha; Yeh, Syun-Ru; Prendergast, George C; Muller, Alexander J; Malachowski, William P

Inhibition Mechanisms of Human Indoleamine 2,3 Dioxygenase 1

人类吲哚胺2,3-双加氧酶1的抑制机制

Lewis-Ballester, Ariel; Karkashon, Shay; Batabyal, Dipanwita; Poulos, Thomas L; Yeh, Syun-Ru

Reaction intermediates in the heme degradation reaction by HutZ from Vibrio cholerae

霍乱弧菌HutZ介导的血红素降解反应中的反应中间体

Uchida, Takeshi; Sekine, Yukari; Dojun, Nobuhiko; Lewis-Ballester, Ariel; Ishigami, Izumi; Matsui, Toshitaka; Yeh, Syun-Ru; Ishimori, Koichiro

Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase

人类色氨酸 2,3-双加氧酶催化和底物介导细胞稳定的分子基础

Ariel Lewis-Ballester, Farhad Forouhar, Sung-Mi Kim, Scott Lew, YongQiang Wang, Shay Karkashon, Jayaraman Seetharaman, Dipanwita Batabyal, Bing-Yu Chiang, Munif Hussain, Maria Almira Correia, Syun-Ru Yeh, Liang Tong

Structural Study of a Flexible Active Site Loop in Human Indoleamine 2,3-Dioxygenase and Its Functional Implications

人吲哚胺2,3-双加氧酶柔性活性位点环的结构研究及其功能意义

Álvarez, Lucía; Lewis-Ballester, Ariel; Roitberg, Adrián; Estrin, Darío A; Yeh, Syun-Ru; Marti, Marcelo A; Capece, Luciana

The first step of the dioxygenation reaction carried out by tryptophan dioxygenase and indoleamine 2,3-dioxygenase as revealed by quantum mechanical/molecular mechanical studies

量子力学/分子力学研究揭示了色氨酸双加氧酶和吲哚胺2,3-双加氧酶催化的双加氧反应的第一步。

Capece, Luciana; Lewis-Ballester, Ariel; Batabyal, Dipanwita; Di Russo, Natali; Yeh, Syun-Ru; Estrin, Dario A; Marti, Marcelo A