日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Leveraging Omeprazole PBPK/PD Modeling to Inform Drug-Drug Interactions and Specific Recommendations for Pediatric Labeling

利用奥美拉唑 PBPK/PD 模型指导药物相互作用研究,并为儿科用药标签提供具体建议

Soliman, Amira; Rodriguez-Vera, Leyanis; Alarcia-Lacalle, Ana; Pippa, Leandro F; Subhani, Saima; Lukacova, Viera; Duconge, Jorge; de Moraes, Natalia V; Vozmediano, Valvanera

Histological Assessment of Intestinal Changes Induced by Liquid Whey-Enriched Diets in Pigs.

液态乳清强化日粮对猪肠道组织变化的组织学评估

Mhalhel Kamel, Cavallaro Mauro, Pansera Lidia, Ledesma Leyanis Herrera, Levanti Maria, Germanà Antonino, Sutera Anna Maria, Tardiolo Giuseppe, Zumbo Alessandro, Aragona Marialuisa, Montalbano Giuseppe

New insights into the role of VKORC1 polymorphisms for optimal warfarin dose selection in Caribbean Hispanic patients through an external validation of a population PK/PD model

通过对群体药代动力学/药效动力学模型进行外部验证,深入了解VKORC1多态性在加勒比西班牙裔患者华法林最佳剂量选择中的作用。

Rodríguez-Fernández, Karine; Reynaldo-Fernández, Gledys; Reyes-González, Stephanie; de Las Barreras, Camila; Rodríguez-Vera, Leyanis; Vlaar, Cornelis; Monbaliu, Jean-Christophe M; Stelzer, Torsten; Duconge, Jorge; Mangas-Sanjuan, Victor

Interspecies Brain PBPK Modeling Platform to Predict Passive Transport through the Blood-Brain Barrier and Assess Target Site Disposition

跨物种脑部PBPK建模平台用于预测药物通过血脑屏障的被动转运并评估靶位点处置

Mehta, Parsshava; Soliman, Amira; Rodriguez-Vera, Leyanis; Schmidt, Stephan; Muniz, Paula; Rodriguez, Monica; Forcadell, Marta; Gonzalez-Perez, Emili; Vozmediano, Valvanera

Applying Physiologically Based Pharmacokinetic Modeling to Interpret Carbamazepine's Nonlinear Pharmacokinetics and Its Induction Potential on Cytochrome P450 3A4 and Cytochrome P450 2C9 Enzymes

应用生理药代动力学模型解释卡马西平的非线性药代动力学及其对细胞色素P450 3A4和细胞色素P450 2C9酶的诱导潜力

Yin, Xuefen; Cicali, Brian; Rodriguez-Vera, Leyanis; Lukacova, Viera; Cristofoletti, Rodrigo; Schmidt, Stephan

Leveraging Physiologically Based Modelling to Provide Insights on the Absorption of Paliperidone Extended-Release Formulation under Fed and Fasting Conditions

利用生理模型深入了解帕利哌酮缓释制剂在空腹和饱腹状态下的吸收情况

Subhani, Saima; Lukacova, Viera; Kim, Chaejin; Rodriguez-Vera, Leyanis; Muniz, Paula; Rodriguez, Monica; Cristofoletti, Rodrigo; Van Os, Sandra; Suarez, Elena; Schmidt, Stephan; Vozmediano, Valvanera

Single nucleotide polymorphisms associated with wine fermentation and adaptation to nitrogen limitation in wild and domesticated yeast strains

与葡萄酒发酵和野生及驯化酵母菌株对氮限制的适应相关的单核苷酸多态性

Kessi-Pérez, Eduardo I; Acuña, Eric; Bastías, Camila; Fundora, Leyanis; Villalobos-Cid, Manuel; Romero, Andrés; Khaiwal, Sakshi; De Chiara, Matteo; Liti, Gianni; Salinas, Francisco; Martínez, Claudio

Open-label phase I/II clinical trial of SARS-CoV-2 receptor binding domain-tetanus toxoid conjugate vaccine (FINLAY-FR-2) in combination with receptor binding domain-protein vaccine (FINLAY-FR-1A) in children

一项针对儿童的开放标签 I/II 期临床试验,研究 SARS-CoV-2 受体结合域-破伤风类毒素结合疫苗 (FINLAY-FR-2) 与受体结合域-蛋白疫苗 (FINLAY-FR-1A) 联合用药的疗效。

Puga-Gómez, Rinaldo; Ricardo-Delgado, Yariset; Rojas-Iriarte, Chaumey; Céspedes-Henriquez, Leyanis; Piedra-Bello, Misleidys; Vega-Mendoza, Dania; Pérez, Noelvia Pestana; Paredes-Moreno, Beatriz; Rodríguez-González, Meiby; Valenzuela-Silva, Carmen; Sánchez-Ramírez, Belinda; Rodríguez-Noda, Laura; Pérez-Nicado, Rocmira; González-Mugica, Raul; Hernández-García, Tays; Fundora-Barrios, Talía; Echevarría, Martha Dubet; Enriquez-Puertas, Juliet María; Infante-Hernández, Yenicet; Palenzuela-Díaz, Ariel; Gato-Orozco, Evelyn; Chappi-Estévez, Yanet; Francisco-Pérez, Julio Cesar; Suarez-Martinez, Miladi; Castillo-Quintana, Ismavy C; Fernandez-Castillo, Sonsire; Climent-Ruiz, Yanet; Santana-Mederos, Darielys; García-Vega, Yanelda; Toledo-Romani, María Eugenia; Doroud, Delaram; Biglari, Alireza; Valdés-Balbín, Yury; García-Rivera, Dagmar; Vérez-Bencomo, Vicente

BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism

自闭症患者未接受治疗和接受药物治疗的血清 BDNF、proBDNF 和 IGF-1 水平

Maria de Los Angeles Robinson-Agramonte, Bernadeta Michalski, Belkis Vidal-Martinez, Leyanis Ramos Hernández, Mabel Whilby Santiesteban, Margaret Fahnestock

Assessment of the clinical utility of pharmacogenetic guidance in a comprehensive medication management service

评估药物遗传学指导在综合药物管理服务中的临床实用性

Rodríguez-Escudero, Idaliz; Cedeño, Julio A; Rodríguez-Nazario, Ileana; Reynaldo-Fernández, Gledys; Rodríguez-Vera, Leyanis; Morales, Niretzy; Jiménez-Vélez, Braulio; Ruaño, Gualberto; Duconge, Jorge